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Vaccine Detail

Allogeneic B7.1/HLA-A1 Transfected Tumor Cell Vaccine
Vaccine Information
  • Vaccine Name: Allogeneic B7.1/HLA-A1 Transfected Tumor Cell Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: Recombinant vector vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: Human
  • Host Species as Laboratory Animal Model: Human
  • Description: An allogeneic whole cell vaccine, derived from irradiated allogenic tumor cells manipulated to express human B7.1 (CD80 antigen) and human leukocyte antigen (HLA) A1, with potential antitumor activity. Vaccination with allogeneic B7.1/HLA-A1 transfected tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor cell proliferation. (NCIT_C70985).
Host Response
References
NCIT_C70985: [https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C70985]