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Vaccine Detail
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Folate-FITC Vaccine |
| Vaccine Information |
- Vaccine Name: Folate-FITC Vaccine
- Target Pathogen: Cancer
- Target Disease: Cancer
- Product Name: EC 17
- Vaccine Ontology ID: VO_0007537
- Type: Conjugate vaccine
- Status: Clinical trial
- Host Species for Licensed Use: Human
- Host Species as Laboratory Animal Model: Human
- FOLR1
gene engineering:
- Type: Recombinant protein preparation
- Description:
- Detailed Gene Information: Click Here.
- Description: A conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity. Folate-FITC binds to folate receptors, which are overexpressed on the surfaces of many cancer cells including kidney and ovarian cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate, circulating anti-fluorescein antibodies may recognize and bind to the FITC moiety, resulting in antibody-dependent cellular cytotoxicity. (NCIT_C62479).
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| Host Response |
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| References |
NCIT_C62479: [https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C62479]
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