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Vaccine Detail
Xenogeneic Tyrosinase DNA Vaccine |
Vaccine Information |
- Vaccine Name: Xenogeneic Tyrosinase DNA Vaccine
- Target Pathogen: Cancer
- Target Disease: Cancer
- Vaccine Ontology ID: VO_0007123
- Type: DNA vaccine
- Status: Clinical trial
- Host Species for Licensed Use: Human
- Host Species as Laboratory Animal Model: Human
- Tyrosinase
gene engineering:
- Type: Recombinant protein preparation
- Description:
- Detailed Gene Information: Click Here.
- Tyrosinase
gene engineering:
- Type: Recombinant protein preparation
- Description:
- Detailed Gene Information: Click Here.
- Description: This is for Melanoma Cancer (NCT00471133).A plasmid DNA vaccine, encoding an epitope of mouse tyrosinase, with potential antineoplastic activity. Administered via intramuscular electroporation, vaccination with xenogeneic tyrosinase DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) immune responses against melanoma cells that express tyrosinase, resulting in decreased tumor growth (Yost, 1985; NCIT_C68839).
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Host Response |
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References |
NCIT_C68839: [https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C68839]
NCT00471133: [https://clinicaltrials.gov/show/NCT00471133]
Yost, 1985: Yost WA. Click stimuli do produce masking-level differences, sometimes. The Journal of the Acoustical Society of America. 1985; 77(6); 2191-2192. [PubMed: 4019903].
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