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Vaccine Detail
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A. pleuropneumoniae apfA vaccine |
| Vaccine Information |
- Vaccine Name: A. pleuropneumoniae apfA vaccine
- Target Pathogen: Actinobacillus pleuropneumoniae
- Target Disease: porcine pleuropneumonia
- Type: Subunit vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- Host Species as Laboratory Animal Model: Mice
- apfA
gene engineering:
- Type: Recombinant protein preparation
- Description: Purified recombinant ApfA elicited an elevated humoral immune response and conferred robust protection against challenges with A. pleuropneumoniae serovar 1 strain 4074 and serovar 7 strain WF83 in mice (Zhou et al., 2013).
- Detailed Gene Information: Click Here.
- Immunization Route: Intraperitoneal injection (i.p.)
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| Host Response |
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| References |
Zhou et al., 2013: Zhou Y, Li L, Chen Z, Yuan H, Chen H, Zhou R. Adhesion protein ApfA of Actinobacillus pleuropneumoniae is required for pathogenesis and is a potential target for vaccine development. Clinical and vaccine immunology : CVI. 2013; 20(2); 287-294. [PubMed: 23269417].
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