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Vaccine Detail

Pentacel
Vaccine Information
  • Vaccine Name: Pentacel
  • Target Pathogen: Haemophilus influenzae
  • Target Disease: Meningitis
  • Product Name: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate) Vaccine
  • Tradename: Pentacel
  • Manufacturer: Sanofi Pasteur Ltd
  • Vaccine Ontology ID: VO_0000084
  • CDC CVX code: 120
  • Type: Subunit vaccine + Inactivated or "killed" vaccine
  • Status: Licensed
  • Location Licensed: USA (License #1726), Canada
  • Host Species for Licensed Use: Human
  • Adjuvant:
  • Preservative: 2 phenoxy ethanol
  • Allergen: Polymyxin B, Neomycin
  • Preparation: Corynebacterium diphtheriae is grown in modified Mueller’s growth medium. After purification by ammonium sulfate fractionation, the diphtheria toxin is detoxified with formaldehyde and diafiltered (FDA: Pentacel).
  • Immunization Route: Intramuscular injection (i.m.)
  • Storage: Store at 2° to 8°C (35° to 46°F). Do not freeze.
  • Approved Age for Licensed Use: 6 weeks to 4 years of age.
  • Contraindication: A severe allergic reaction (e.g., anaphylaxis) after a previous dose of Pentacel vaccine, any ingredient of this vaccine, or any other tetanus toxoid, diphtheria toxoid, pertussis-containing vaccine, inactivated poliovirus vaccine or H influenzae type b vaccine is a contraindication (FDA: Pentacel).
  • Description: It consists of a Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus (DTaP-IPV) component and an ActHIB® vaccine component. Pentacel vaccine is indicated for active immunization against diphtheria, tetanus, pertussis, poliomyelitis and invasive disease due to Haemophilus influenzae type b (FDA: Pentacel).
Host Response
References
FDA: Pentacel: FDA: Pentacel [http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm172502.htm]