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Vaccine Detail

Adacel
Vaccine Information
  • Vaccine Name: Adacel
  • Target Pathogen: Bordetella pertussis
  • Target Disease: Whooping Cough
  • Product Name: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed
  • Tradename: Adacel
  • Manufacturer: Sanofi Pasteur, Ltd (USA: License #1726)
  • Vaccine Ontology ID: VO_0000005
  • CDC CVX code: 20, 115
  • Type: Toxoid vaccine
  • Status: Licensed
  • Location Licensed: USA: License #1726; Canada
  • Host Species for Licensed Use: Human
  • Antigen: Pertussis
  • Adjuvant: aluminum phosphate vaccine adjuvant
  • Preparation: Clostridium tetani is grown in modified Mueller-Miller casamino acid medium without beef heart infusion. Tetanus toxin is detoxified with formaldehyde and purified by ammonium sulfate fractionation and diafiltration. Diphtheria and tetanus toxoids are individually adsorbed onto aluminum phosphate (FDA: Adacel).
  • Immunization Route: Intramuscular injection (i.m.)
  • Storage: Adacel vaccine should be stored at 2° to 8°C (35° to 46°F). DO NOT FREEZE
  • Approved Age for Licensed Use: Adacel vaccine is indicated for active booster immunization for the prevention of tetanus, diphtheria and pertussis as a single dose in persons 11 through 64 years of age.
  • Contraindication: A severe allergic reaction (e.g., anaphylaxis) after a previous dose of Adacel vaccine or any other tetanus toxoid, diphtheria toxoid or pertussis containing vaccine or any other component of this vaccine is a contraindication to vaccination with Adacel vaccine (FDA: Adacel).
  • Description: It is a sterile liquid suspension of tetanus and diphtheria toxoids and acellular pertussis components adsorbed onto aluminum phosphate, for intramuscular administration.
Host Response
References
FDA: Adacel: FDA: Adacel [http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm172481.htm]