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Vaccine Detail
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Pseduorabies Subunit Glycoprotein C Vaccine |
| Vaccine Information |
- Vaccine Name: Pseduorabies Subunit Glycoprotein C Vaccine
- Target Pathogen: Pseudorabies virus
- Target Disease: Aujeszky's disease
- Vaccine Ontology ID: VO_0004155
- Type: Subunit vaccine
- Status: Research
- UL44
gene engineering:
- Type: Recombinant protein preparation
- Description: Psuedorabies glycoprotein C was purified from pseudorabies infected cell lysates (Katayama et al., 1997).
- Detailed Gene Information: Click Here.
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Pig Response
- Vaccination Protocol: Pigs of each group were immunized intramuscularly with one ml of the different trial vaccines at two week intervals. Control pigs were vaccinated with unifected cell lysate antigens (Katayama et al., 1997).
- Challenge Protocol: One week after immunization pigs were challenged intranasally with 10^6 TCID50 of PRV Yamagata S-81 strain (Katayama et al., 1997).
- Efficacy: Immunized pigs had a high (87.5%) rate of survival against lethal PRV challenge (Katayama et al., 1997).
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| References |
Katayama et al., 1997: Katayama S, Okada N, Yoshiki K, Okabe T, Shimizu Y. Protective effect of glycoprotein gC-rich antigen against pseudorabies virus. The Journal of veterinary medical science / the Japanese Society of Veterinary Science. 1997; 59(8); 657-663. [PubMed: 9300361].
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