• Vaccine Name: M. gallisepticum TM-1 Protein Subunit Vaccine
• Target Pathogen: Mycoplasma gallisepticum
• Target Disease: Chronic respiratory disease
• Vaccine Ontology ID: VO_0011515
• Type: Subunit vaccine
• Status: Research
• TM-1 gene engineering:
  • Type: Recombinant protein preparation
  • Description:
  • Detailed Gene Information: Click Here.
• Adjuvant:
  • Adjuvant name:
  • VO adjuvant ID: VO_0000127
• Immunization Route: Subcutaneous injection

Chicken Response

• Host Strain: SPF
• Vaccination Protocol: Eight-week-old specific pathogen-free (SPF) chickens were immunized subcutaneously in the right thigh with the TM-1 polypeptide, suspended in a mixture of 1 ml of PBS and 1 ml of an aluminium hydroxide adjuvant (Saito et al., 1993).
• Challenge Protocol: Four weeks later, the immunized chickens were challenged intranasally with 0.5 ml of a suspension of 10^6 c.f.u, ml- 1 of M.g. KP13 strain 27 (Saito et al., 1993).
• Efficacy: Only one of five immunized chickens harboured viable M.g. cells in its sinuses after being killed 5 days after challenge with M.g. (Saito et al., 1993).