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Rous sarcoma virus vaccine vector |
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Vaxvec ID |
20 |
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Vaccine Vector Name |
Rous sarcoma virus vaccine vector |
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Alternative Names |
RSV |
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Vector VO ID |
VO_0001104
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Description |
Rous sarcoma virus is classified as a simple retrovirus. More specifically, this virus is an avian retrovirus. Its genome includes 9312 nucleotide sequences and encompasses four major open reading frames (ORFs) 5′-gag-pol-env-src-3′. Its three beginning open reading frames--gag, pol, and env--are not necessary to a large extent to generate a retrovirus that functions well. |
| Related Vaccine(s) |
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| References |
Schwartz et al., 1983: Schwartz DE, Tizard R, Gilbert W. Nucleotide sequence of Rous sarcoma virus. Cell. 1983; 32(3); 853-869. [PubMed: 6299578].
Wirth et al., 2013: Wirth T, Parker N, Ylä-Herttuala S. History of gene therapy. Gene. 2013; 525(2); 162-169. [PubMed: 23618815].
Withers and Beemon, 2011: Withers JB, Beemon KL. The structure and function of the rous sarcoma virus RNA stability element. Journal of cellular biochemistry. 2011; 112(11); 3085-3092. [PubMed: 21769913].
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