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Vaccine Comparison

NYVAC-PRV- gII/ gp50
Vaccine Information
  • Vaccine Ontology ID: VO_0004778
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: Baboon
  • GII gene engineering:
    • Type: Recombinant vector construction
    • Description: A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 (Brockmeier and Mengeling, 1996).
    • Detailed Gene Information: Click Here.
  • gp50 gene engineering:
    • Type: Recombinant vector construction
    • Description: A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 (Brockmeier and Mengeling, 1996).
    • Detailed Gene Information: Click Here.
  • Preparation: (Brockmeier and Mengeling, 1996) A NYVAC vaccinia vector containing genes for PRV gII and gp50 .
  • Immunization Route: Intramuscular injection (i.m.)
References
Brockmeier and Mengeling, 1996: Brockmeier SL, Mengeling WL. Comparison of the protective response induced by NYVAC vaccinia recombinants expressing either gp50 or gII and gp50 of pseudorabies virus. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 1996; 60(4); 315-317. [PubMed: 8904669].
Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine
Vaccine Information
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Raccoon
  • glycoprotein G gene engineering:
    • Type: Gene mutation
    • Description: This glycoprotein E/G/UL23 mutant is from Suid herpesvirus 1 (Weigel et al., 2003).
    • Detailed Gene Information: Click Here.
  • glycoprotein E gene engineering:
    • Type: Gene mutation
    • Description: This glycoprotein E/G/UL23 mutant is from Suid herpesvirus 1 (Weigel et al., 2003).
    • Detailed Gene Information: Click Here.
  • UL23 gene engineering:
    • Type: Gene mutation
    • Description: This glycoprotein E/G/UL23 mutant is from Suid herpesvirus 1 (Weigel et al., 2003).
    • Detailed Gene Information: Click Here.
  • Immunization Route: intranasal immunization
References
Weigel et al., 2003: Weigel RM, Hahn EC, Scherba G. Survival and immunization of raccoons after exposure to pseudorabies (Aujeszky's disease) virus gene-deleted vaccines. Veterinary microbiology. 2003; 92(1-2); 19-24. [PubMed: 12488067].
Pseudorabies virus gp50/gp63 mutant vaccine
Vaccine Information
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Pig
  • gp50 gene engineering:
    • Type: Gene mutation
    • Description: This gp50/gp63 mutant is from Suid herpesvirus 1 (Peeters et al., 1994).
    • Detailed Gene Information: Click Here.
  • gp63 gene engineering:
    • Type: Gene mutation
    • Description: This gp50/gp63 mutant is from Suid herpesvirus 1 (Peeters et al., 1994).
    • Detailed Gene Information: Click Here.
  • Immunization Route: Intramuscular injection (i.m.)
References
Peeters et al., 1994: Peeters B, Bouma A, de Bruin T, Moormann R, Gielkens A, Kimman T. Non-transmissible pseudorabies virus gp50 mutants: a new generation of safe live vaccines. Vaccine. 1994; 12(4); 375-380. [PubMed: 8178562].
Pseudorabies virus UL50 mutant vaccine
Vaccine Information
  • Vaccine Ontology ID: VO_0002989
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Pig
  • UL50 gene engineering:
    • Type: Gene mutation
    • Description: This UL50 mutant is from Suid herpesvirus 1 (Jöns et al., 1997).
    • Detailed Gene Information: Click Here.
  • Immunization Route: intranasal immunization
References
Jöns et al., 1997: Jöns A, Gerdts V, Lange E, Kaden V, Mettenleiter TC. Attenuation of dUTPase-deficient pseudorabies virus for the natural host. Veterinary microbiology. 1997; 56(1-2); 47-54. [PubMed: 9228681].
Pseudorabies virus US3 mutant vaccine
Vaccine Information
  • Vaccine Ontology ID: VO_0002990
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Pig
  • US3 gene engineering:
    • Type: Gene mutation
    • Description: This US3 mutant is from Suid herpesvirus 1 (Kimman et al., 1994).
    • Detailed Gene Information: Click Here.
  • Immunization Route: intranasal immunization
References
Kimman et al., 1994: Kimman TG, De Wind N, De Bruin T, de Visser Y, Voermans J. Inactivation of glycoprotein gE and thymidine kinase or the US3-encoded protein kinase synergistically decreases in vivo replication of pseudorabies virus and the induction of protective immunity. Virology. 1994; 205(2); 511-518. [PubMed: 7975253].
Psuedorabies virus glycoprotein M mutant vaccine
Vaccine Information
  • Vaccine Ontology ID: VO_0002985
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Pig
  • glycoprotein M gene engineering:
    • Type: Gene mutation
    • Description: This glycoprotein M mutant is from Pseudorabies virus (Dijkstra et al., 1997).
    • Detailed Gene Information: Click Here.
  • Immunization Route: intranasal immunization
References
Dijkstra et al., 1997: Dijkstra JM, Gerdts V, Klupp BG, Mettenleiter TC. Deletion of glycoprotein gM of pseudorabies virus results in attenuation for the natural host. The Journal of general virology. 1997; 78 ( Pt 9); 2147-2151. [PubMed: 9292000].