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Vaccine Comparison
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Bovine herpesvirus 1 UL23 mutant vaccine |
Bovine herpesvirus 1 US8 (gE) mutant vaccine |
| Vaccine Information |
Vaccine Information |
- Product Name: B8-D53
- Vaccine Ontology ID: VO_0002949
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Cow
- UL23
gene engineering:
- Type: Gene mutation
- Description: This UL23 mutant is from Bovine herpesvirus 1 (Kit et al., 1985).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
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- Vaccine Ontology ID: VO_0002950
- Type: Live, attenuated vaccine
- Status: Research
- US8
gene engineering:
- Type: Gene mutation
- Detailed Gene Information: Click Here.
- Preparation: The bovine herpesvirus 1 (BHV1) strain Za is a conventionally attenuated strain with a 2.7 kb deletion that encompasses the complete coding region for glycoprotein E (gE) (Kaashoek et al., 1995).
- Immunization Route: intranasal immunization
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| References |
References |
Kit et al., 1985: Kit S, Qavi H, Gaines JD, Billingsley P, McConnell S. Thymidine kinase-negative bovine herpesvirus type 1 mutant is stable and highly attenuated in calves. Archives of virology. 1985; 86(1-2); 63-83. [PubMed: 2994602].
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Kaashoek et al., 1995: Kaashoek MJ, Moerman A, Madić J, Weerdmeester K, Maris-Veldhuis M, Rijsewijk FA, van Oirschot JT. An inactivated vaccine based on a glycoprotein E-negative strain of bovine herpesvirus 1 induces protective immunity and allows serological differentiation. Vaccine. 1995; 13(4); 342-346. [PubMed: 7793128].
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