- Vaccine Ontology ID: VO_0002951
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Cow
- glycoprotein G
gene engineering:
- Type: Gene mutation
- Description: This glycoprotein G mutant is from Bovine respiratory syncytial virus (Schmidt et al., 2002).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
|
- Vaccine Ontology ID: VO_0004289
- Type: Recombinant vector vaccine
- Status: Licensed
- Host Species as Laboratory Animal Model: Calves
- glycoprotein G
gene engineering:
- Type: Recombinant vector construction
- Description: The gE gene was replaced by a gene encoding the G protein of BRSV in a BHVI vector (Schrijver et al., 1997).
- Detailed Gene Information: Click Here.
- Vector: BHVI (Schrijver et al., 1997)
- Immunization Route: intranasal immunization
|
Schmidt et al., 2002: Schmidt U, Beyer J, Polster U, Gershwin LJ, Buchholz UJ. Mucosal immunization with live recombinant bovine respiratory syncytial virus (BRSV) and recombinant BRSV lacking the envelope glycoprotein G protects against challenge with wild-type BRSV. Journal of virology. 2002; 76(23); 12355-12359. [PubMed: 12414977].
|
Schrijver et al., 1997: Schrijver RS, Langedijk JP, Keil GM, Middel WG, Maris-Veldhuis M, Van Oirschot JT, Rijsewijk FA. Immunization of cattle with a BHV1 vector vaccine or a DNA vaccine both coding for the G protein of BRSV. Vaccine. 1997; 15(17-18); 1908-1916. [PubMed: 9413101].
|
