DNAVAxDB: DNA Vaccine database

V1Jns DNA vaccine plasmid
DNA Vaccine Plasmid ID	132
DNA Vaccine Plasmid Name	V1Jns DNA vaccine plasmid
Plasmid VO ID	VO_0005044
Promoter Names	CMV
Plasmid Description	Employs the promoter, enhancer, and intron A of human CMV and the termination and polyadenylation sequences of bovine growth hormone within a plasmid backbone (Lekutis et al., 1997)
Related Vaccine(s)	HIV DNA vaccine VlJns-tPA-gp120 (Human Immunodeficiency Virus) Human papillomavirus DNA vaccine VlJns-Ll encoding L1 (Human Papillomavirus) Herpes simplex virus DNA vaccine encoding gD and gB from HSV-2 strain Curtis (Herpes simplex virus type 1 and 2) HIV recombinant vector vaccine MVA-gag encoding gag (Human Immunodeficiency Virus)
References	*Lekutis et al., 1997:* Lekutis C, Shiver JW, Liu MA, Letvin NL. HIV-1 env DNA vaccine administered to rhesus monkeys elicits MHC class II-restricted CD4+ T helper cells that secrete IFN-gamma and TNF-alpha. Journal of immunology (Baltimore, Md. : 1950). 1997; 158(9); 4471-4477. [PubMed: 9127013].