VIOLIN: Vaccine Investigation and Online Information Network

Community Efforts

Vaccine Ontology: A community-based effort to develop the Vaccine Ontology (VO) for vaccine data standardization and automated reasoning. VO is being developed by collaboration with the Ontology for Biomedical Investigations (OBI), the National Center for Biomedical Ontology (NCBO) and the Infectious Disease Ontology (IDO) initiative.

VIOLIN News >>

3/22-25/2010: Allen Xiang attended the OBI Spring 2010 Workshop at Vancouver, Canada. He presented a use case on vaccine protection investigation using ontology (OBI and VO)-based ANOVA analysis of literature mined data.
11/10-12/2009: Oliver He and Allen Xiang attended the “UTMB Sealy Center for Vaccine Development Symposium” in Galveston, Texas. Dr. He presented a talk in how to use VIOLIN and VO to analyze Brucella vaccines.
7/24-26/2009: Oliver and two lab members attended the 1st International Conference on Biomedical Ontology (ICBO) conference in Buffalo, NY. Two posters and one software demo were presented, all related to Vaccine Ontology development and application.

Latest Vaccine Publications >>

Chaisson RE, Harrington M. How research can help control tuberculosis World hospitals and health services : the official journal of the International Hospital Federation 46(1):33-40 2010 [PMID: 20614683]
He S, Yang L, Lv Z, Hu W, Cao J, Wei J, Sun X, Yang J, Zheng H, Wu Z. Molecular and functional characterization of a mortalin-like protein from Schistosoma japonicum (SjMLP/hsp70) as a member of the HSP70 family Parasitology research 2010 [PMID: 20602114]

Vaccine News >>

Flu vaccine reactions unforeseeable
6minutes Dec 31, 1969 19:00
Whooping cough cases doubled in July in Santa Clara County
San Jose Mercury News Dec 31, 1969 19:00
Scientists develop new gel that regenerates & restores some types of decayed teeth
allvoices Dec 31, 1969 19:00

Statistics: The VIOLIN vaccine database contains 510 vaccines or vaccine candidates for 91 pathogens by manual curation from 1113 peer-reviewed papers. It also contains 24,345 vaccine-related abstracts and 10,317 full text documents.

Publication: Zuoshuang Xiang, Thomas Todd, Kim P. Ku, Bethany L. Kovacic, Charles B. Larson, Fang Chen, Andrew P. Hodges, Yuying Tian, Elizabeth A. Olenzek, Boyang Zhao, Lesley A. Colby, Howard G. Rush, Janet R. Gilsdorf, George W. Jourdian, Yongqun He. VIOLIN: Vaccine Investigation and Online Information Network. Nucleic Acids Res. 2008 Jan;36(Database issue):D923-8. [NAR] [PubMed] [PDF].