Vaxar: Vaccine Animal Responses
Laboratory animal models have been widely used for vaccine research and development. According to the Animal Efficacy Rule (also known as the “two animal rule”) instituted by the USA Department of Health and Human Services (HHS) and Food and Drug Administration (FDA), development and approval of human therapeutics (e.g., vaccines) requires demonstration of a "reasonably well-understood mechanism" and that at least two different animal species be used to demonstrate "response[s] predictive for humans."
Vaxar is a VIOLIN program that focuses on investigation of vaccine-induced animal responses. To use Vaxar, you can start to select pathogens and items you wish to compare below: