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Canine parvovirus

Table of Contents
  1. General Information
    1. NCBI Taxonomy ID
    2. Disease
    3. Introduction
  2. Vaccine Related Pathogen Genes
    1. VP1 (Protective antigen)
    2. VP2 (Protective antigen)
  3. Vaccine Related Host Genes
    1. IgG Fc fragment
  4. Vaccine Information
    1. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.20)
    2. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.21)
    3. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.22)
    4. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.25)
    5. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.29)
    6. Canine Coronavirus-Parvovirus Modified Live Virus Vaccine (USDA: 14R1.20)
    7. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.20)
    8. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.21)
    9. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.25)
    10. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.29)
    11. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47C5.20)
    12. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47C5.29)
    13. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46B9.21)
    14. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.25)
    15. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.29)
    16. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47L9.20)
    17. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.21)
    18. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.26)
    19. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.27)
    20. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.20)
    21. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.22)
    22. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J9.20)
    23. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46L9.27)
    24. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live Virus, Live Canarypox Vector Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J9.R1)
    25. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live Virus; Canarypox Vector Vaccine (USDA: 1591.R1)
    26. Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46P9.27)
    27. Canine Distemper-Adenovirus Type 2-Measles-Parainfluenza Modified Live Virus Vaccine (USDA: 1341.20)
    28. Canine Distemper-Adenovirus Type 2-Parainfluenza Modified Live Virus Vaccine (USDA: 13C1.20)
    29. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.20)
    30. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.21)
    31. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.22)
    32. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.23)
    33. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.25)
    34. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.27)
    35. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.28)
    36. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.29)
    37. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.T0)
    38. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4637.29)
    39. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4639.25)
    40. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47K1.20)
    41. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.27)
    42. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.28)
    43. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.20)_
    44. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.22)
    45. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.23)
    46. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.21)
    47. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.22)
    48. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J8.20)
    49. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Canarypox Vector Vaccine (USDA: 13D1.R1)
    50. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Live Canarypox Vector Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.R1)
    51. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus-Rabies Modified Live & Killed Virus Vaccine (USDA: 13G9.20)
    52. Canine Distemper-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14D7.20)
    53. Canine Distemper-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14D9.27)
    54. Canine Distemper-Hepatitis-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 47P9.22)
    55. Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.20)
    56. Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.27)
    57. Canine parvovirus CPMV-PARVO1 protein vaccine
    58. Canine parvovirus DNA vaccine pGT36VP1
    59. Canine Parvovirus Modified Live Virus Vaccine-Leptospira Canicola Icterohaemorrhagiae Bacterin (USDA: 47B1.20)
    60. Parvovirus Killed Virus Vaccine (USDA: 18P5.20)
    61. Parvovirus Killed Virus Vaccine (USDA: 18P5.21)
    62. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.20)
    63. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.21)
    64. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.22)
    65. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.23)
    66. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.25)
    67. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.29)
    68. RECOMBITEK Canine Parvo
  5. References
I. General Information
1. NCBI Taxonomy ID:
10788
2. Disease:
Canine parvovirus infection
3. Introduction
Canine parvovirus type 2 (CPV2, colloquioally parvo) is a contagious virus mainly affecting dogs. The disease is highly infectious and is spread from dog to dog by direct or indirect contact with their feces. It can be especially severe in puppies that are not protected by maternal antibodies or vaccination. It has two distinct presentations, a cardiac and intestinal form. The common signs of the intestinal form are severe vomiting and dysentery. The cardiac form causes respiratory or cardiovascular failure in young puppies. Treatment often involves veterinary hospitalization. Vaccines can prevent this infection, but mortality can reach 91% in untreated cases.

CPV2 is a non-enveloped single-stranded DNA virus. It has an icosahedral symmetry. The genome is about 5000 nucleotides long. CPV2 continues to evolve, and the success of new strains seems to depend on extending the range of hosts affected and improved binding to its receptor, the canine transferrin receptor. CPV2 has a high rate of evolution, possibly due to a rate of nucleotide substitution that is more like RNA viruses such as Influenzavirus A. In contrast, FPV seems to evolve only through random genetic drift (Wiki: Canine parvovirus).
1. VP1
  • Gene Name : VP1
  • Sequence Strain (Species/Organism) : Canine parvovirus
  • VO ID : VO_0011055
  • NCBI Gene ID : 1489587
  • Locus Tag : CPVgp3
  • Taxonomy ID : 10788
  • Gene Starting Position : 2284
  • Gene Ending Position : 2361
  • Gene Strand (Orientation) : ?
  • DNA Sequence : Show Sequence
    >gi|9627186:2284-2361 Canine parvovirus, complete genome
    GATGGCACCTCCGGCAAAGAGAGCCAGGAGAGGTAAGGGTGTGTTAGTAAAGTGGGGGGAGGGGAAAGAT
    TTAATAAC
  • Molecule Role : Protective antigen
  • Molecule Role Annotation : This study shows that a plasmid DNA (pGT36VP1) encoding the full length VP1 region of canine parvovirus (CPV) induces immunity that protects dogs against challenge with virulent virus (Jiang et al., 1998).
  • Related Vaccine(s): Canine parvovirus DNA vaccine pGT36VP1
2. VP2
  • Gene Name : VP2
  • Sequence Strain (Species/Organism) : Canine parvovirus
  • VO ID : VO_0011054
  • NCBI Gene ID : 1489588
  • Locus Tag : CPVgp4
  • Taxonomy ID : 10788
  • Gene Starting Position : 2782
  • Gene Ending Position : 4536
  • Gene Strand (Orientation) : ?
  • DNA Sequence : Show Sequence
    >gi|9627186:2782-4536 Canine parvovirus, complete genome
    ACCAATGAGTGATGGAGCAGTTCAACCAGACGGTGGTCAACCTGCTGTCAGAAATGAAAGAGCTACAGGA
    TCTGGGAACGGGTCTGGAGGCGGGGGTGGTGGTGGTTCTGGGGGTGTGGGGATTTCTACGGGTACTTTCA
    ATAATCAGACGGAATTTAAATTTTTGGAAAACGGATGGGTGGAAATCACAGCAAACTCAAGCAGACTTGT
    ACATTTAAATATGCCAGAAAGTGAAAATTATAGAAGAGTGGTTGTAAATAATATGGATAAAACTGCAGTT
    AACGGAAACATGGCTTTAGATGATATTCATGCACAAATTGTAACACCTTGGTCATTGGTTGATGCAAATG
    CTTGGGGAGTTTGGTTTAATCCAGGAGATTGGCAACTAATTGTTAATACTATGAGTGAGTTGCATTTAGT
    TAGTTTTGAACAAGAAATTTTTAATGTTGTTTTAAAGACTGTTTCAGAATCTGCTACTCAGCCACCAACT
    AAAGTTTATAATAATGATTTAACTGCATCATTGATGGTTGCATTAGATAGTAATAATACTATGCCATTTA
    CTCCAGCAGCTATGAGATCTGAGACATTGGGTTTTTATCCATGGAAACCAACCATACCAACTCCATGGAG
    ATATTATTTTCAATGGGATAGAACATTAATACCATCTCATACTGGAACTAGTGGCACACCAACAAATATA
    TACCATGGTACAGATCCAGATGATGTTCAATTTTATACTATTGAAAATTCTGTGCCAGTACACTTACTAA
    GAACAGGTGATGAATTTGCTACAGGAACATTTTTTTTTGATTGTAAACCATGTAGACTAACACATACATG
    GCAAACAAATAGAGCATTGGGCTTACCACCATTTCTAAATTCTTTGCCTCAATCTGAAGGAGCTACTAAC
    TTTGGTGATATAGGAGTTCAACAAGATAAAAGACGTGGTGTAACTCAAATGGGAAATACAAACTATATTA
    CTGAAGCTACTATTATGAGACCAGCTGAGGTTGGTTATAGTGCACCATATTATTCTTTTGAGGCGTCTAC
    ACAAGGGCCATTTAAAACACCTATTGCAGCAGGACGGGGGGGAGCGCAAACATATGAAAATCAAGCAGCA
    GATGGTGATCCAAGATATGCATTTGGTAGACAACATGGTCAAAAAACTACCACAACAGGAGAAACACCTG
    AGAGATTTACATATATAGCACATCAAGATACAGGAAGATATCCAGAAGGAGATTGGATTCAAAATATTAA
    CTTTAACCTTCCTGTAACGAATGATAATGTATTGCTACCAACAGATCCAATTGGAGGTAAAACAGGAATT
    AACTATACTAATATATTTAATACTTATGGTCCTTTAACTGCATTAAATAATGTACCACCAGTTTATCCAA
    ATGGTCAAATTTGGGATAAAGAATTTGATACTGACTTAAAACCAAGACTTCATGTAAATGCACCATTTGT
    TTGTCAAAATAATTGTCCTGGTCAATTATTTGTAAAAGTTGCGCCTAATTTAACAAATGAATATGATCCT
    GATGCATCTGCTAATATGTCAAGAATTGTAACTTACTCAGATTTTTGGTGGAAAGGTAAATTAGTATTTA
    AAGCTAAACTAAGAGCCTCTCATACTTGGAATCCAATTCAACAAATGAGTATTAATGTAGATAACCAATT
    TAACTATGTACCAAGTAATATTGGAGGTATGAAAATTGTATATGAAAAATCTCAACTAGCACCTAGAAAA
    TTATA
  • Molecule Role : Protective antigen
  • Molecule Role Annotation : A vaccine based upon a recombinant plant virus (CPMV-PARVO1), displaying a peptide derived from the VP2 capsid protein of canine parvovirus (CPV), has previously been described. To date, studies with the vaccine have utilized viable plant chimaeric particles (CVPs). Results show that the inactivated CVP is able to protect dogs from a lethal challenge with CPV following parenteral immunization with the vaccine. Dogs immunized with the inactivated CPMV-PARVO1 in adjuvant displayed no clinical signs of disease and shedding of CPV in faeces was limited following CPV challenge. (Langeveld et al., 2001).
  • Related Vaccine(s): Canine parvovirus CPMV-PARVO1 protein vaccine
1. IgG Fc fragment
  • Gene Name : IgG Fc fragment
  • Sequence Strain (Species/Organism) : Canis lupus familiaris
  • NCBI Gene ID : 403462
  • NCBI Protein GI : 55742701
  • Protein Accession : NP_001002976
  • Taxonomy ID : 9615
  • Chromosome No : 17
  • Gene Starting Position : 59093049
  • Gene Ending Position : 59102001
  • Gene Strand (Orientation) : +
  • Protein Name : Fc fragment of IgG, high affinity Ia, receptor (CD64)
  • Protein pI : 6.67
  • Protein Weight : 39657.45
  • Protein Length : 372
  • Protein Note : Also known as FCGAMMARI
  • DNA Sequence : Show Sequence
    >gi|357579614:59093049-59102001 Canis lupus familiaris chromosome 17, CanFam3.1, whole genome shotgun sequence
    TCAATGTCTTGCATGTTACAGACTTCACTGTTCCCATCAGCTTGGAGATAACATGTGGCTCTTGACAGTT
    CTACTCCTTTGGGGTAAGTTGGGTATAGAGGGATAGCTAGAAGGGTAGTGGCTCTGACTGTCTTCCTTTG
    GTATCCTAGACTAGAACTCATGAATGTGGGGACAACTATATCTGTGCTTCCATGATTTATTTATGCTCAT
    TATACCAAAAGCCTGGGAAGAGAGACTTAGTGATAACATTTAGCCTGGAAGCATCATATCAAAATAAAGC
    CTCATCAATAACCATCCATAGGTTGTTCAGTACCACTAGTCCCTGATTTTGAGAAAGGGGGTAGAGAGAG
    ACTCAAGACACCTAAGCTGGCCCCTTAGAGTCTATATTAGTTTTGTCTCCTTGATTCTCCTTTCCTTGTC
    ATCTCCCACTGACCAACTTATGTCTCTCTTCTTTGGTCTCTTACAGTCCCAGCTGGTGCACAAACAGGTG
    AGTAATCTTTAACTTTATTTCTCTTTCTCTGCCACATTCCTGCTTCTGAAGGGTGAGTTTTGTTTTCCTG
    AAGAAGAGAGTATAGGGAGAGGATAGAAACAAGAAAGATTTATAAATTATGTAAAATCTCCTATATTCGG
    AGTATGATTTTAATAAAATCCTGGTTTTTAAAGTTTCTCTCTAAGATTTCCTGAAAAAGCCCTGAGCTTT
    GGACTAAATGCCTATGTGTATATAATAGCAGGAAAAGGCCAGAATTGCAAAACTATAGACGTAGCTCTTC
    CAACATTCCTCAAACCTGTCCCCTTTAGAAGAAAGCTGAGTACTTTCTTTTTAGAGAGAACCAAGCAAGT
    ACTGAAGGCTTCTTTCTAAGTGAGGAGTTTGAGCCTCTATTTCCAAAGCAGATGCTAATTAAGTCCTGAG
    TTTAACCCTCAGGGACAGTATAGCACAGAGGATGAGAGAACCAGCTCCAATCAACTTGCCTGGGTTTAAA
    ACTCTTCTGCTTTACCAACAATGAAAACTAAATTAGTCATTTGTTTCTTCTTCTTCCTTTTTTTTTTTTT
    TTTTAGTCATTTGTTTCTTAGGAATCCCAAATCTCCAACATCTAGATGTAGATTTAATAACATGAACGGA
    GCTCTGTGCATGGGGTGTGGATGCTCTCAGTAGCTAGCTTTTACAGGTTCCCACTTGCTTATTTTTCAGT
    CTCATCTAACTATATATTTTTTACCTTGTGCCTTCCACAAAACCTTATTAATTACTCAGATCTTCCTTTT
    ATTCCACTTGGTCTTCTTTTTTCCCTTCTTTTTCTTTTTCGTTTTCTTTCTTTCTTTCTTTCTTTTTTTT
    TTTTTAATCCCCAAGCAGACCCCGTAAAGGCAGTGATCACCTTGCAGCCTCCATGGGTCAGTGTATTCCA
    AGAGGAAAGTGTAACCTTATGGTGCGAGGGACCCCATTTGCCTGGGGACAGCTCTACACAGTGGTTTCTC
    AATGGCACAGCCACTCAGACCTTGACCCCCAGATACAGAATCGCTGCTGCCAGTGTCAATGACAATGGTG
    AATACAGGTGCCAGACAGGTCTCTCAGTCCTAAGTGACCCGATACAGCTGGAAATCCACAGAGGTAAGTA
    GGGCATGGAACAGGAGAGCTGGAAATCACAAGGTCTCCCTTTATGTTTTCCCCTTTATCGATGCCAGATA
    TGTGTGTTTTCATTTATTGGAGTGTAAGTTTCAGCTCTGTGTGCCTACTAGGTGAAATTAAGTCCAAATA
    CTTAGAATATCACATGAGGGTCCTTAAACTGTGCCCCAATAGCACCCCTCTGGGACAGCTGTGAGCAGGG
    TATCTAGTGTAAAACTCAGACCCTAAGATTTTATTATTTAAAATGATCTAATTTTGTTGAAAATCTGCAC
    ACAGTAAATAAGAATTCAGAAAAATGTACAATGATGAACAATGAAATCTCTCTTCCACCTCAGACTCCTA
    GTCCCATGGTCACCTTCTATAGAAATAAAACTGTTAATATTTATGAACCGTAAAAAACAGTGGTTGATGA
    GGCACCTGGGGGCTCAGTCAGTTAAGTGTCTACCTTCAGCTCAGGTCATGATCCCAGGGCCCTGGGGTTG
    AGCCCCATATTGTGCCTCCTGCTCAACAGGGAGAACAGGGAGTCTGCTTCTCCTTCCCCCTCTGCTGTTC
    CCTCTGCTTGTGCTCTCTTGCTTTCTCTCTCAAAGAAATGAATTTTTTTTTTTAAATGGTTGGTTGAATA
    CTCTATATACTGTTCTACACCTTGCTTTTATCACTTAAAATACCTTGGAGGTCTATTTAAATCAATAGAG
    ATCTACCACGAACTTTCAAATGTCTGCCATATGGCTGTGCTGTAACTGATTTAATCATTTACCTATTAGT
    AAACTTGTAGTATATTTCCAGTTTTTTGTTTTTACAGTCCTGCAATAGACATCTCTATACTTATAGACTG
    GAGCACATTTCATAATATATCTGTAAGATAATATTCTGGACATGAAATTACTTTTGAGACTAAGCATTTT
    AAATGTTGATGAATGGAAGGGAACCCCCCCCCCAACATATCCACTTAAATTTGTAAAAGATTTCCATTTG
    TCAAGAAATGGAAACTGAATGTTTCATTATTCAGTATAAATCATTCAAATGTGTTGGGGGAGAAGAAGTA
    AGGGGAGGGGCAGAAAGAGAGTGAGGAGGAGTCTCCCTACCAAGCAGGGAGCCAGGGGGCACAGGACTTG
    GGGATTATGACCTGAGTTGAAGTCAGAGGCTTAACTGACTGTCCCTTGGACAGAACTGTTTTTACAAGAT
    ATTTTATATAGTTGAAGTAGAAGAAGTGCTTTATAGTTCAAGTGACAAAAAAAGTGAAACAGGGCTAGGA
    AGAGTCCACTTTCTTTGCCTCTGTACAGACTGTAGAAGCCCCAGCATTAATGACTTACTGAGAATAATAT
    ATTTTACGTTTTTTTTAAAAAGCTTTATTTATTTATTTGAGAGAGCGAGAGAGAGAGAGAGAGAGAGAGA
    GAGCATGATGAGTGGGAGTGGCAGAGAGAGAGGGAGAGAGAATCTCAAGCGGACTCCACGCTGAGTTCAG
    AGTCTGTCTCAGGACAGTGAGATCATGACCTGAACCAAAATCAAGGATTGGATGTTTAACCAACTGAGCC
    ACTCAGGGGCCCCACTATTTCGGGCCTCTTACAGGTAGTACTGCTATGAACATTTTTCTTTTAAGATGTT
    ATTTTTTTAAGTAATCTCTACACCTAACATGGGGCTGGAACTCATAATCCCCAGATCAAGAGTTGCACAC
    TGTATCAGCTGAGCCAGCCAGGTGCCCCCACTGTGGACATTTTGATACCTGTTTTTTGGTGCACTTATGT
    ATACATATCTGTTGATATGCCTAGGAGTGGAATTGCTCGGTCACAAAATGTACATCTATTTGTTCAGCTT
    TAATTTTCCAAAGTGGTTATACCATATTACACTTCTACAGTGGAATGTAAGAGTTCTGGTTCCTTTTCAT
    CCTCATCAACACTCGGTGCTTTCTTTCTTTTCTTCTTTCTTTCTCTTTCTCTCTCTCTCTCTCTCTCTCT
    CTCTTTCTTTCTTTTTTTTTTTTTCAAGATTTTATTTATTTATTCATGAGAGATGAAGAGAGAGGCAGAG
    ACACAGGCAGAGGAAGAAGCAGGCTCTCTGCAGGAGCCTGATGTGGGACTTGATCCCCAACCCTGGGATC
    AGGCCCTGAGTCAAAGGCAGATGCTTAACCACTAAGCCACCCAGGCATCCCTCTTCTTTCTTTCTTTCTT
    TCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTCTTTCTTTTTCTTTCTTT
    TTAACATACAGAGGTTTCTATATCTTTCAGTTTAGTCATTCTGGTGCATGTGCAGTAGTCATCACATAGC
    TTTAATTTGCATTTTCCTGAAGACTCATGACATCAAGCATTTTCTACATTTATTACTTATTTGGATATCC
    TCTTTTGTAAAATACCCATCTAGGTTTTTTTTGTCAATTTTTCTTTATTGTTGTCTTTCCTTATCAACTT
    GCAGGATCTCTGTAGTTTGGACATGAGTCCTTTTTCAAGTGTTGCAAATATCTTTCACGCTGTGGCTTGT
    CTTTTCACTATCTATGCTGTTTTTTCAGTGAAAAAAAGTGCTTACATTTACTGTAGTACAGTATAAATAC
    ATCAGGTTTTGGGGTTGGTGCTCTCTATGCCCTTATTTAAAAATGTTTTGCCACAGCTAACCAGCAGAGG
    AGAGTTCACCTGTAGGTACACTAACTCTGTCACTTCAGTTAAATCTGTATGTGCTGAGACCACAAAAATA
    TAGCTGGTTTGAGGATCTATGAGCATCCCAATCCTGCTTTAAGGTGATGAAGATGGAAAGAATGGCTTTT
    GAGGAGGAAATTAATAATGTCTGCTAAAAAGCTGTATCCTGAAATTTTTGATAATACTCCCAACTATCAT
    TTAAGACTAAATCTTTTTAATTTTCATTAGTATGTATATAATTCTTTTTTCTTTTTCTTTCCTCATGAAT
    TATTTAGAAGTGATTTAGGAAGGTGGCTTTTTGTTACTGATTTCTAATTTTATGTTAAATATGGTATCAG
    TTCTTTAGTATTTGTTGAAAATTGCTTGTGGCTTAGTACATACTCGGTATTTTTAACTGTTGCATGTGTG
    TTTGGAAAGTATGTGAATTTTCTTTAAACTATAGCTTCTATATAAATCCACAAAAATCAACTCTATTCAT
    TGTGTCATTCAGATATGTTATATCATCACTAGTATTTTTGACAGTGTCTGATCCCATCATGTTTGTGGAT
    ATATAAAGCTAAGGTGTTTGTGTGTTGGGGTACTGTAATCTTTGAGCACCTCTTGGTTGGGAATGGGAAT
    AAGGGAGAGAAGAGCATTATATTTAGAAACACTGTGACAGCATCCAAAACTATAAAAGTCATGCTACATA
    TACCACTGGAATACCTCTGCCTTCTGTTCTTAGGTAAATTCTGGAGGGGGAAAAACACTACTGTCCCTTT
    TTGTCTTTTGTCCTTTAAGAACCTCCTCCCCATTTAGCCAAATCAACTGCTCCAGGGAAAGAAAAAGGAA
    GCATTTTTTTGGTTATGTGTAGAGATGTACATCAAAAGGGAGGGCCCCTTGGACTTGGAGCTTGTTTTTA
    GCAGCTAGATCACTGATCTGCGCATGTGTGTATATTCTGTCAATTTAGGGGCACATATACATCTGGAAAT
    GTTTGCTATTCTGTGTGCTTGTCTTGGGACAAACAAGTATGTGGGATGCCATTAACATAGTAGTCAGGAG
    TTGGAGTGTTTTAGTTTTTTTTATTGCTGTGTAACAAATTACTACAAACACAGCAGTTTAAAACAATGTA
    TATTTATTATCTTTCCATGGGTCAGGAGTCTCAGCACAGCTTAGCTGGGTGCTCTGCAGGGGCTGCAGTC
    AGGGTATTGACTGAGTTGTGTTCCTTCCTGCAGATCTTCCAAGCTCACATGGTCGTTGGCAGAATTTAGA
    ATTCAGTTCTTTATGTTATAAGCCTGAGGTCCCCACCTTTTAGCTGGCTGTCAGTTGGAAGTAATCTCAG
    CTCCTCCAGGCAGGCCTTTGCCAGATGGCCCTCTCCCAACATAGTGGCTTACTTCTTCAGGGCCAGTGGG
    AGACTCTCAGTCCAGTCAGCTAAGAGAGTCATATAACGTAACCTCATCGTGACAGAGACATCCTGTAACC
    TTTTTCATATCCTGTTCATTAAGCAAGTCTCAGGTTACACATACACCCAAGGGGATTACACAAGGGTGTG
    ACACACTGGAGTCATCTTAGAATATTGCCTACCACATACAGTAAAATGTTTTTATCCCAACCAACTTCTG
    AAATCTGGCAAGGGAAGTAAGAAGGGCCTGTGTGCATGGCTGCTTGTAAAGACTACTTTTCTTCCCAAAA
    AAGCTAAAGATAATTGGGGGATGGGCAATAGGCCTCAAATTCGGCAGAGCTCTGAGGTTGAAATGTTGAA
    AGAAAAAAAGATAAGAAATCCACCAGGGCCCAGCTTCAGCCTCCTTGTCCCTCTGCTACTGTATACATAC
    ATTTTGGGTATATATTTTCCAGATTGGCTAATACTCCAGGTCTCTGGCAGAGTCTTCACGGAAGGGGAAC
    CTCTGACTTTGAGGTGTCATGGATGGAATAATAAGCTGGTGTACAATGTGCTTTTCTACCAAAATGGCAC
    AGTCTTGAAGTTTTCTCCTCAGAATTCTGAATTTACCATTCTGAAAACCACCCTACATCACAATGGCATC
    TATCACTGCTCAGCCATGGGAAAGCATCGCTACGAATCAGCAGGAGTATCTATCACTATAAAAGGTATGT
    ATCTGAATAGTCACAGAGCTCTAGTTTTAAGGACCATTATAAATCATCACTTCAGTTTGCAAGAGAAGAG
    ACTTAAGTTCCAGAGAGGTAGCTATCTCACTGAAGGCCATACAGTGACCAGTGGCTGGGCCAGAACTGGA
    ACTGAAGTCTTCTGGGCCTCCGGTCTATTGCTCTTTCCAGTAAATCGCAATGCCCATCAGTAATCCCAGG
    AGCTAACATGAAGGGCAGGGCATAGTGAGGATCTATTTCATCATTTTAGTTGCAAGGAATAGAGATTTAC
    TTGAGGTATGTAGGAGGGTTATTAAAAAATAACTCAATGGAGTCTCATAAAAAGCTCCATAGAATCAGAA
    GCCATGAAGACATTAGGACTTGGTTTTACATTTTATCTATCTCTCAGGGGCAATATGGACTCTCTGATTC
    TACTTCTCTCTGAACATGTGCTAACTAAGCAGCTTTCTCTGTTCCAGCTTACATGAGGGCCTCATTGTGG
    TTCTTTCATCTTAGTACTCATATAGTTATAGTTTCTGTTTGAAAAAGAATTCATTCCGATGGGAAAAAGA
    GGATTGTCCCAGATTATCTTTGGGGGAAGTGAGTAACACAAGTAATAAGTCACTGACCTGGCGAGTAGTG
    TGTGTCAGTGTCCACTCCTGGTGGACCATTACCAAAAGGCATGGTCACATACTCAGTAATATGACTATTC
    AGGGAAGCATGGACTGTGTGGAGGTATTCTTTTTTTTTTTAAAAAAAGATTTTATTTTATTTATTTATTC
    ATGAGAGATACAGAGGGGGGAGGGCAGAGACACAGGCAGAGGGAGAAGCAGGCTCCATGCAAGGGAGCCC
    AGTGTGACGTGGGACTCAATCCCAATTATGCCCTGGGCCGAAGGCAGGCGCTAAACCACTGAGCCACCCA
    GGGATCCCTGGAGGTATTCTCCCCAGTAGGAAATGAGGAAGTTGGCAACTATAAGAGTATCTATGAGGAA
    ACCCCAAGAATGCCTCTCTGCTGAAAGTGGGAAAATTTGTCTTACAGATGCATTCTCTAGGGGCAGGTTT
    CCCAAGGAGGAACCAGGTATATTTTCTGTAAAAAGAACCTTGACACTGAAGCAGGCAACCCTGTCCCCAT
    CAACTTTTCTTTAGAGCTATTTCCAGCCCCAGTGCTAAAAGCATCCTTGTCATCACCCATCCTGGAGGGG
    CATGTGGTCAATCTGAGCTGTGAAACAAAGCTCCTCCTACAGAGACCTGGTTTGCAACTTTACTTCTCCT
    TCTACATGGGCAGTAAGACCCTGCTGAGCAGGAATACATCCTCTGAATACCAGATACTAACAGCTAAGAA
    AGAAGATTCAGGGTTATACTGGTGCGAGGCTACCACAGAAGATGGCAATGTCGTCAAGCGCAGCCCTGAG
    TTGGAGCTTCAAGTGGTTGGTGAGCATGAGGGGAACTGACAGGCACAAGGAGAAGATGCTCCCTTTTCTC
    CTTTGGGGCTGAGGTTTGTTTAAGGGGATTTCATGGCCCACCCAGGAAAAACCCATGAAGGGGCATTTCC
    ACTTTTGATTCGTAACTTCATTATTCTCATGAGCTCTATTAAGTTTCCTTTCTTAACTCCATTTATTGCC
    TTCCTTTTGTCCTTCTTTTCTTCTTCATTTTCTTTTTCCCCCTGTTCCTCCCCCCACCCTAAAAATCTAA
    TCAATATATTGAGTTCCTTCCATCTGTTGTCATAAATGTGGGGATATGAAGACAGTGGGGTACAGCTCTT
    ACTTCAAGGAGCTCACATGGTAGATTGGTGACGTAGGGAATTTTGTGGATTGCACATAAATACCTGCCCA
    AGTGGCTATATCTGGCTGAGGTAGAGAGACTGTGAGCTCCAAGACAAAGACTCTTTGGGAAAAAAGTTTA
    TCTTCAACCCAAATCCATTTCAGGCATTAAATGGCATAGATGTAGCATTTTTGTCTGAAACTAGGAAGTC
    CACTTAGTAGGCCCTGGCAGTTAAGCTCTTATGAGGAGCCTGCCCCTGGTCTGTACACCATATAACTCAG
    GTGGAGCACCTATCTGCCCCCTGAAATTACCATTGTCTCCACTGGGGACAGGCATACCAGGTGTCAGCCA
    GTATTCCCTCCCAAACATAATTCATCCAGATTCCTCTGCGTTCTAACTAGCATTTCTTCTTGTCATTTTC
    TTTTTCAGGCCCCCAGACACTAACTCCTGTTTGGTTTCACGTCCTTTTCTATGTGGCAATGGGAATGATA
    TTTTTGGTGGATACCATTTTCTGTATGATTATACATAAGGAACTGCAAAGAAAGAAAAAGTGGAATTTAG
    AAATCTCGTTGTACTCTGGTCTTGAGAAAAGAGTAGATTCCTACCTTCAAAAGGAGAGAGATTTAGAAGA
    GCCAAAATATCAGGAACTCGAACAGCTGCAAGAAAAGACACCCCAGAAGCCCCCAGAGGGAGAGCAGCAG
    TAGAGCCCAGGGGGTGCCCATGGATTGAGATGGTGCCTCCCACTTCTTTTTGGTGCGTGCATTGGGGTGC
    AAACACCCAAAAGTTTGAAGACGTTAGAACTCTGAGTCCCATGTCATCTGATTAACTCTGAAA
  • Protein Sequence : Show Sequence
    >gi|55742701|ref|NP_001002976.1| high affinity immunoglobulin gamma Fc receptor I precursor [Canis lupus familiaris]
    MWLLTVLLLWVPAGAQTDPVKAVITLQPPWVSVFQEESVTLWCEGPHLPGDSSTQWFLNGTATQTLTPRY
    RIAAASVNDNGEYRCQTGLSVLSDPIQLGIHRDWLILQVSGRVFTEGEPLTLRCHGWNNKLVYNVLFYQN
    GTVLKFSPQNSEFTILKTTLHHNGIYHCSAMGKHRYESAGVSITIKELFPAPVLKASLSSPILEGHVVNL
    SCETKLLLQRPGLQLYFSFYMGSKTLLSRNTSSEYQILTAKKEDSGLYWCEATTEDGNVVKRSPELELQV
    VGPQTLTPVWFHVLFYVAMGMIFLVDTIFCMIIHKELQRKKKWNLEISLYSGLEKRVDSYLQKERDLEEP
    KYQELEQLQEKTPQKPPEGEQQ
  • Molecule Role : Vaximmutor
  • Related Vaccine(s): Canine parvovirus DNA vaccine pGT36VP1
IV. Vaccine Information
1. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.20)
a. Manufacturer:
Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002122
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
2. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.21)
a. Manufacturer:
Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002123
c. Type:
Live vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
3. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.22)
a. Manufacturer:
Intervet Inc.
b. Vaccine Ontology ID:
VO_0002124
c. Type:
Live vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
4. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.25)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002125
c. Type:
Live vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
5. Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.29)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002126
c. Type:
Live vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
6. Canine Coronavirus-Parvovirus Modified Live Virus Vaccine (USDA: 14R1.20)
a. Manufacturer:
Merial, Inc.
b. Vaccine Ontology ID:
VO_0002121
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
7. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.20)
a. Manufacturer:
Intervet Inc., Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002136
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
8. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.21)
a. Manufacturer:
Wyeth, Intervet Inc., Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002137
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
9. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.25)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002138
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
10. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.29)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002139
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
11. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47C5.20)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002241
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
12. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47C5.29)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002242
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
13. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46B9.21)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002219
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
14. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.25)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002231
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
15. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.29)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002234
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
16. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47L9.20)
a. Manufacturer:
Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002246
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
17. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.21)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002230
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
18. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.26)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002232
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
19. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.27)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002233
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
20. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.20)
a. Manufacturer:
Intervet Inc., Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002226
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
21. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.22)
a. Manufacturer:
Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002227
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
22. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J9.20)
a. Manufacturer:
Intervet Inc.
b. Vaccine Ontology ID:
VO_0002229
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
23. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46L9.27)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002236
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
24. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live Virus, Live Canarypox Vector Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J9.R1)
a. Manufacturer:
Merial, Inc.
b. Vaccine Ontology ID:
VO_0002235
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
25. Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live Virus; Canarypox Vector Vaccine (USDA: 1591.R1)
a. Manufacturer:
Merial, Inc.
b. Vaccine Ontology ID:
VO_0002135
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
26. Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46P9.27)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002237
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
27. Canine Distemper-Adenovirus Type 2-Measles-Parainfluenza Modified Live Virus Vaccine (USDA: 1341.20)
a. Manufacturer:
Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002095
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
28. Canine Distemper-Adenovirus Type 2-Parainfluenza Modified Live Virus Vaccine (USDA: 13C1.20)
a. Manufacturer:
Boehringer Ingelheim Vetmedica, Inc., Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002100
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
29. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.20)
a. Manufacturer:
Intervet Inc., Aceto Pharma Corp.
b. Vaccine Ontology ID:
VO_0002101
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
30. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.21)
a. Manufacturer:
Wyeth, Boehringer Ingelheim Vetmedica, Inc., Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002102
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
31. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.22)
a. Manufacturer:
Intervet Inc., Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002103
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
32. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.23)
a. Manufacturer:
Intervet Inc.
b. Vaccine Ontology ID:
VO_0002104
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
33. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.25)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002105
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
34. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.27)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002106
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
35. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.28)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002107
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
36. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.29)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002108
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
37. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.T0)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002110
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
38. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4637.29)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002211
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
39. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4639.25)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002214
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
40. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47K1.20)
a. Manufacturer:
Intervet Inc., Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002245
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
41. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.27)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002215
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
42. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.28)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002216
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
43. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.20)_
a. Manufacturer:
Intervet Inc., Pfizer, Inc.
b. Type:
Live, attenuated vaccine
c. Status:
Licensed
d. Location Licensed:
USA
e. Host Species for Licensed Use:
Gray wolf
44. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.22)
a. Manufacturer:
Intervet Inc.
b. Vaccine Ontology ID:
VO_0002209
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
45. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.23)
a. Manufacturer:
Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002210
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
46. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.21)
a. Manufacturer:
Wyeth, Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002212
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
47. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.22)
a. Manufacturer:
Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0002213
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
48. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J8.20)
a. Manufacturer:
Boehringer Ingelheim Vetmedica, Inc.
b. Vaccine Ontology ID:
VO_0002228
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
49. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Canarypox Vector Vaccine (USDA: 13D1.R1)
a. Manufacturer:
Merial, Inc.
b. Vaccine Ontology ID:
VO_0002109
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
50. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Live Canarypox Vector Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.R1)
a. Manufacturer:
Merial, Inc.
b. Vaccine Ontology ID:
VO_0002217
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
51. Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus-Rabies Modified Live & Killed Virus Vaccine (USDA: 13G9.20)
a. Manufacturer:
Intervet Inc.
b. Vaccine Ontology ID:
VO_0002111
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
52. Canine Distemper-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14D7.20)
a. Manufacturer:
Intervet Inc.
b. Vaccine Ontology ID:
VO_0002117
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
53. Canine Distemper-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14D9.27)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002118
c. Type:
Live, attenuated vaccine; Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
54. Canine Distemper-Hepatitis-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 47P9.22)
a. Manufacturer:
Boehringer Ingelheim Vetmedica, Inc.
b. Vaccine Ontology ID:
VO_0002247
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
55. Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.20)
a. Manufacturer:
Intervet Inc.
b. Vaccine Ontology ID:
VO_0002113
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
56. Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.27)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0002114
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
57. Canine parvovirus CPMV-PARVO1 protein vaccine
a. Vaccine Ontology ID:
VO_0011464
b. Type:
Subunit vaccine
c. Status:
Research
d. Antigen
Canine parvovirus VP2
e. Gene Engineering of VP2
  • Type: Recombinant protein preparation
  • Description: CPMV–PARVO1 contains a 17-amino acid peptide (DGAVQPDGGQPAVRNER) corresponding to residues 3 to 19 from VP2 of canine parvovirus, inserted between residues 22 and 23 of the S protein of CPMV. Each virion contains 60 copies of this peptide and 1 μg chimera contains approximately 20 ng of peptide. The construction, propagation and purification of CPMV–PARVO1 virions (and wild type CPMV) was carried out. In addition, the virus particles were inactivated by irradiation with UV254 light during the purification, according to the following procedure: after resuspension of the PEG/NaCl pellet and clarification, the concentration of particles was measured by spectrophotometry, and the virus-containing supernatant diluted to 1 mg/ml (Langeveld et al., 2001).
  • Detailed Gene Information: Click here.
f. Immunization Route
Subcutaneous injection
g. Dog Response
  • Vaccination Protocol: Dogs were kept in four groups of five or six animals, A–D, each group in a separate room. Groups A, B and C (six dogs in each) were immunized subcutaneously above the shoulder blades on days 0 and 28 with either CPMV–PARVO1, 3L17–KLH or wild type CPMV, respectively, in Quil-A®/Alhydrogel®. A fourth group (D) of five dogs was left unvaccinated. Inoculation sites were checked daily for adverse reactions (Langeveld et al., 2001).
  • Challenge Protocol: On day 42, all 23 dogs were challenged with CPV by the oronasal route [19], by distributing CPV onto their eyes, noses and mouths (1.5 ml/dog). Blood was collected prior to immunization, following immunization (days 28 and 38) and following challenge (day 48 and 57), and sera collected and stored at −20°C. Rectal swabs were performed with cotton wool swab sticks and stored at −20°C prior to analysis for the presence of CPV (Langeveld et al., 2001).
  • Efficacy: Dogs immunized with the inactivated CPMV-PARVO1 in adjuvant displayed no clinical signs of disease and shedding of CPV in faeces was limited following CPV challenge (Langeveld et al., 2001).
58. Canine parvovirus DNA vaccine pGT36VP1
a. Vaccine Ontology ID:
VO_0011462
b. Type:
DNA vaccine
c. Status:
Research
d. Antigen
Canine parvovirus VP1
e. Gene Engineering of VP1
  • Type: DNA vaccine construction
  • Description: CPV viral DNA was used as template to amplify the entire VP1 fragment, including VP2, by polymerase chain reaction (PCR). Two deoxyoligonucleotides, coding and noncoding strand primers were synthesized. The product was then electrophoresed in a 0.8% agarose/TAE gel. The band containing the PCR product was excised from the agarose gel by QIAGEN QIAquickTM spin columns (QIAGEN GmbH, Hilden, Germany) and digested simultaneously with BamHI and Not1 (New England Biolabs, Beverly, MA, USA). The digested VP1 fragment was ligated into BamHIINotI digested pGT36 (kindly provided by Dr David Curiel, University of Alabama, Birmingham, AL, USA), a derivative of pCDNA3, which has a CMV promoter and kanamycin resistance gene. Kanamycin resistance clones were screened for appropriate restriction digestion patterns and one clone, designated as pGT36VP1, was then sequenced using an Applied Biosystems Model 373A Automated Sequencer (Perkin-Elmer/Applied Biosysterns Division, Folster City, CA, USA) (Jiang et al., 1998).
  • Detailed Gene Information: Click here.
f. Vector:
plasmid vector pGT36
g. Immunization Route
Intramuscular injection (i.m.)
h. Dog Response
  • Vaccination Protocol: Four mix breed dogs, 9 months of age, from a single litter were injected with doses of 200, 400, 600 or 800 /lg pGT36VPl in a total volume of 1 ml phosphate buffered saline (PBS, 0.067 M, pH 7.2). One negative control sibling was injected with 1 ml PBS. All injections were administered i.m. at the right quadriceps muscle. Blood samples were collected weekly. All dogs were reinjected on week 16 with the same dose of DNA used initially at the same site and the negative control was injected with PBS (Jiang et al., 1998).
  • Challenge Protocol: Challenge infections with virulent CPV were performed in a HEIPA filtered, environmentally controlled kennel facility at the College of Veterinary Medicine, Auburn University. The challenge strains of CPV (AU-H3-WS-93) consist of equal amounts of three virulent CPV slrains, AU-H3 (CPV-2), WS (CPV-2a) and 93 (CPV-2b) at a dose of 105 TCID(50) (tissue culture infectious dose) per ml. All challenge strains were purified from fecal extracts. The challenge dose was given intranasally (0.5 ml in each nostril) and orally (1.0 ml). The dogs were monitored three times daily for clinical signs including attitude, appetite, stool consistency, temperature and vomiting (Jiang et al., 1998).
  • Efficacy: All pGT36VP1 vaccinated dogs were protected against infection after virulent CPV challenge regardless of dose and the unvaccinated control dog was fully susceptible (Jiang et al., 1998).
  • Host Gene Response of IgG Fc fragment
    • Gene Response: NAV vaccinated dogs showed an increase of serum IgG titer starting 1 week post-injection which peaked at week 2 and remained detectable for at least 14 weeks. The non-immunized control dog did not show an antibody response at any point pre-challenge (Jiang et al., 1998).
    • Detailed Gene Information: Click here.
59. Canine Parvovirus Modified Live Virus Vaccine-Leptospira Canicola Icterohaemorrhagiae Bacterin (USDA: 47B1.20)
a. Manufacturer:
Boehringer Ingelheim Vetmedica, Inc.
b. Vaccine Ontology ID:
VO_0002240
c. Status:
Licensed
d. Location Licensed:
USA
e. Host Species for Licensed Use:
Gray wolf
60. Parvovirus Killed Virus Vaccine (USDA: 18P5.20)
a. Manufacturer:
Intervet Inc., Pfizer, Inc., Novartis Animal Health US, Inc.
b. Vaccine Ontology ID:
VO_0001752
c. Type:
Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
61. Parvovirus Killed Virus Vaccine (USDA: 18P5.21)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0001753
c. Type:
Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
62. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.20)
a. Manufacturer:
Boehringer Ingelheim Vetmedica, Inc., Intervet Inc., VacciCel, Inc., Neotech, LLC
b. Vaccine Ontology ID:
VO_0001754
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
63. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.21)
a. Manufacturer:
Wyeth, Boehringer Ingelheim Vetmedica, Inc., Intervet Inc.
b. Vaccine Ontology ID:
VO_0001755
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
64. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.22)
a. Manufacturer:
Intervet Inc., Pfizer, Inc., Merial, Inc.
b. Vaccine Ontology ID:
VO_0001756
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
65. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.23)
a. Manufacturer:
Wyeth, Intervet Inc., Pfizer, Inc.
b. Vaccine Ontology ID:
VO_0001757
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
66. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.25)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0001758
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
67. Parvovirus Modified Live Virus Vaccine (USDA: 18M1.29)
a. Manufacturer:
Wyeth
b. Vaccine Ontology ID:
VO_0001759
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Gray wolf
68. RECOMBITEK Canine Parvo
a. Tradename:
RECOMBITEK Canine Parvo
b. Vaccine Ontology ID:
VO_0001123
c. Type:
Live, attenuated vaccine
d. Status:
Licensed
e. Host Species for Licensed Use:
Dog
f. Immunization Route
Intramuscular injection (i.m.)
g. Description
Modified live virus
V. References
1. Jiang et al., 1998: Jiang W, Baker HJ, Swango LJ, Schorr J, Self MJ, Smith BF. Nucleic acid immunization protects dogs against challenge with virulent canine parvovirus. Vaccine. 1998; 16(6); 601-607. [PubMed: 9569471].
2. Langeveld et al., 2001: Langeveld JP, Brennan FR, Martínez-Torrecuadrada JL, Jones TD, Boshuizen RS, Vela C, Casal JI, Kamstrup S, Dalsgaard K, Meloen RH, Bendig MM, Hamilton WD. Inactivated recombinant plant virus protects dogs from a lethal challenge with canine parvovirus. Vaccine. 2001; 19(27); 3661-3670. [PubMed: 11395200].
3. Wiki: Canine parvovirus: Canine parvovirus [http://en.wikipedia.org/wiki/Canine_parvovirus]