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Publications

Note: This page provides the collection of journal articles published since September 2007 when the NIAID grant 1R01AI081062 was awarded to support the VIOLIN, the Vaccine Ontology (VO), and related research. Proceeding papers are usually not included. The collection may not be comprehensive and updated.

Search online for hits citing the grant 1R01AI081062 that supports this VIOLIN project:

Search for PubMed for Dr. Yongqun "Oliver" He's vaccine or ontology related publications between 2008 and 2018: https://www.ncbi.nlm.nih.gov/pubmed/?term=(yongqun+he)+AND+(vaccine+OR+ontology)+AND+2008%3A2018%5Bdp%5D

 

The following is a list of papers based on different categories (Note: one paper may appears in more than one category):


The VIOLIN system in general:

He Y, Racz R, Sayers S, Lin Y, Todd T, Hur J, Li X, Patel M, Zhao B, Chung M, Ostrow J, Sylora A, Dungarani P, Ulysse G, Kochhar K, Vidri B, Strait K, Jourdian GW, Xiang Z. Updates on the web-based VIOLIN vaccine database and analysis system. Nucleic Acids Research. 2014. 42 (D1): D1124-D1132. doi: 10.1093/nar/gkt1133. [NAR] [PubMed PMID: 24259431] [PDF]

Xiang Z, Todd T, Ku KP, Kovacic BL, Larson CB, Chen F, Hodges AP, Tian Y, Olenzek EA, Zhao B, Colby LA, Rush HG, Gilsdorf JR, Jourdian GW, He Y. VIOLIN: Vaccine Investigation and Online Information Network. Nucleic Acids Res. 2008 Jan;36(Database issue):D923-8. [NAR] [PubMed: PMID: 1802504] [PDF].

 


Vaccine design tool Vaxign:

Papers introducting Vaxign:

Xiang Z, He Y. Genome-wide prediction of vaccine targets for human herpes simplex viruses using Vaxign reverse vaccinology. BMC Bioinformatics. 2013, 14(Suppl 4):S2 (8 March 2013). PMID: 23514126; PMCID: PMC3599071.

He Y, Xiang Z, Mobley HLT. Vaxign: the first web-based vaccine design program for reverse vaccinology and an application for vaccine development.J Biomed Biotechnol. 2010;2010:297505. Epub 2010 Jul 4. [PMID:20671958] [Journal Link]

Xiang Z, He Y. 2009. Vaxign: a web-based vaccine target design program for reverse vaccinology. Procedia in Vaccinology. Volume 1, Issue 1, Pages 23-29.

He Y. Genome-based computational vaccine discovery by reverse vaccinology (Chapter 5); in book: Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines, edited by Darren R. Flower, Yvonne Perrie. Publisher: Springer, New York, 2013. ISBN-13: 978-1461450696. ISBN 978-1-4614-5070-2 (eBook). Links in: Google eBook, and Amazon book.

Selected papers citing Vaxign:

As of June 2018, Vaxign has been cited for appoximately 200 times as shown in a Google Scholars search. Below is a list of papers that we participated

Wang Y, Wen Z, Pan X, Briles DE, He Y, Zhang JR. Novel immunoprotective proteins of Streptococcus pneumoniae identified by opsonophagocytosis killing screen. Infect Immun. 2018 Jun 11. pii: IAI.00423-18. PMID: 29891544.

Lopera-Madrid J, Osorio JE, He Y, Xiang Z, Adams LG, Laughlin RC, Mwangi W, Subramanya S, Neilan J, Brake D, Burrage TG, Brown WC, Clavijo A, Bounpheng MA. Safety and immunogenicity of mammalian cell derived and modified-vaccinia Ankara vectored African swine fever subunit antigens in swineVeterinary Immunology and Immunopathology. 2017. DOI: 10.1016/j.vetimm.2017.01.004. PMID: 28241999.

Ni Z, Chen Y, Ong E, He Y. Antibiotic resistance determinants-focused Acinetobacter baumannii vaccine design using reverse vaccinologyInternational Journal of Molecular Sciences. 2017, 18(2), 458. PMID: 28230771. PMCID: PMC5343991.

McNamara L, He Y, Yang Z. Using epitope predictions to evaluate efficacy and population coverage of the Mtb72f vaccine for tuberculosis. BMC Immunology. 2010 Mar 30;11(1):18. [PMID: 20353587] [Journal Link]

He Y, Xiang Z. Bioinformatics analysis of Brucella vaccines and vaccine targets using VIOLIN. Immunome Res. 2010 Sep 27;6 Suppl 1:S5. [NAR] [PubMed] [PDF].

 


Vaccine Components:

Protegen: Protective Antigens:

Yang B, Sayers S, Xiang Z, He Y. Protegen: a web-based protective antigen database and analysis system. Nucleic Acids Research. 2010. 2010 Oct 19. [Epub ahead of print]. [PMID: 20959289]

Protegen data analysis:

Ong E, Wong MU, He Y. Identification of new features from known bacterial protective vaccine antigens enhances rational vaccine designFrontiers in Immunology. 2017 Oct 26;8:1382. PMID: 29123525.

He Y, Xiang Z. Bioinformatics analysis of bacterial protective antigens in manually curated Protegen database. Procedia in Vaccinology. 2012. Volume 6. Pages 3 – 9.

Vaxjo: Vaccine Adjuvants:

Sayers S, Ulysse G, Xiang Z, and He Y. Vaxjo: a web-based vaccine adjuvant database and its application for analysis of vaccine adjuvants and their uses in vaccine development.Journal of Biomedicine and Biotechnology. 2012;2012:831486. Epub 2012 Mar 13. PMID: 22505817.

Virmugen: Virulence factors whose mutants are live attenuated vaccines:

Racz R, Chung M, Xiang Z, and He Y. Systematic annotation and analysis of “virmugens” - virulence factors whose mutants can be used as live attenuated vaccines. Vaccine. Available online December 6, 2012. DOI: 10.1016/j.vaccine.2012.11.066.

DNAVaxDB: DNA Vaccine database:

Racz R, Li X, Patel M, Xiang Z, and He Y. DNAVaxDB: the first web-based DNA vaccine database and its data analysis. BMC Bioinformatics. 2014, 15(Suppl 4):S2 (19 March 2014).  doi:10.1186/1471-2105-15-S4-S2.

Vaxvec: Recombinant Vaccine Vector database:

Deng S, Martin C, Patil R, Zhu F, Zhao B, Xiang Z, He Y. Vaxvec: The first web-based recombinant vaccine vector database and its data analysis. Vaccine. 2015 Sep 21. pii: S0264-410X(15)01284-0. doi: 10.1016/j.vaccine.2015.07.113. [Epub ahead of print] PMID: 26403370.

Vaxar: Vaccine Animal Responses:

Todd T*, Dunn N*, Xiang Z, He Y. Vaxar: A web-based database of laboratory animal responses to vaccinations and its application in the meta-analysis of different animal responses to tuberculosis vaccinations. Comparative Medicine. 2016. 66(2):119-28. PMID: 27053566.

 


Ontology development:

VO: Vaccine Ontology:

He Y, Cowell L, Diehl AD, Mobley HL, Peters B, Ruttenberg A, Scheuermann RH, Brinkman RR, Courtot M, Mungall C, Xiang Z, Chen F, Todd T, Colby LA, Rush H, Whetzel T, Musen MA, Athey BD, Omenn GS, Smith B. Proceedings of the 1st International Conference on Biomedical Ontology (ICBO 2009), Buffalo, NY, USA. VO: Vaccine Ontology. The 1st International Conference on Biomedical Ontology (ICBO 2009), Buffalo, NY, USA. Nature Precedings. 2009. http://precedings.nature.com/documents/3553/version/1.

Lin Y, He Y. Ontology representation and analysis of vaccine formulation and administration and their effects on vaccine immune responses. Journal of Biomedical Semantics. 2012, 3:17. PMID: 23256535. PMCID: PMC3639077. (NOTE: This paper can be used for citing VO. We are currently preparing a journal article fully describing VO)

Ozgur A, Xiang Z, Radev D, He Y. Mining of vaccine-associated IFN-γ gene interaction networks using the Vaccine Ontology. Journal of Biomedical Semantics. 2011, 2(Suppl 2):S8. PMID: 21624163. PMCID: PMC3102897. (Note: This paper may also be used for citing VO)

OAE: Ontology of Adverse Events

Yongqun He Y, Sirarat Sarntivijai, Yu Lin, Zuoshuang Xiang, Abra Guo, Shelley Zhang, Desikan Jagannathan, Luca Toldo, Cui Tao and Barry Smith. OAE: The Ontology of Adverse Events. Journal of Biomedical Semantics. 2014, 5:29  doi:10.1186/2041-1480-5-29. PMID: 25093068.PMCID: PMC4120740.

OVAE: Ontology of Vaccien Adverse Events

Marcos E , Zhao B, He Y. The ontology of vaccine adverse events (OVAE) and its usage in representing and analyzing adverse events associated with US-licensed human vaccinesJournal of Biomedical Semantics. 2013 Nov 26;4(1):40. PMID: 24279920.

VICO: Vaccination Informed Consent Ontology:

Lin Y, Zheng J, He Y. VICO: Ontology-based representation and integrative analysis of vaccination informed consent formsJ Biomed Semantics. 2016 Apr 19;7:20. doi: 10.1186/s13326-016-0062-4. PMID: 27099700. PMCID: PMC4837519.

OGSF: Ontology of Genetic Susceptibility Factors, and its use in vaccine adverse event domain:

Lin Y, He Y. The Ontology of Genetic Susceptibility Factors (OGSF) and its application in modeling genetic susceptibility to vaccine adverse events. Journal of Biomedical Semantics. 2014, 5:19. doi:10.1186/2041-1480-5-19. PMID: 24963371. PMCID: PMC4068904.

INO: Interaction Network Ontology

Hur J, Özgür A, Xiang Z, He Y. Development and application of an Interaction Network Ontology for literature mining of vaccine-associated gene-gene interactionsJournal of Biomedical Semantics. 2015, 6:2. doi:10.1186/2041-1480-6-2. PMID: 25785184. PMCID: PMC4362819.

OBCS: Ontology of Biological and Clinical Statistics

Zheng J, Harris MR, Masci AM, Lin Y, Hero A, Smith B, He Y. The Ontology of Biological and Clinical Statistics (OBCS) for Standardized and Reproducible Statistical AnalysisJ Biomed Semantics. 2016. Sep 14;7(1):53. PMID: 27627881. PMCID: PMC5024438.  

Zheng J, Li H, Liu Q, He Y. The Ontology of Biological and Clinical Statistics (OBCS)-based statistical method standardization and meta-analysis of host responses to yellow fever vaccinesQuantitative Biology. 2017. 5(4):291-301.

 


Ontology-based Literature Mining:

Hur J, Ozgur A, He Y. Ontology-based literature mining of E. coli vaccine-associated gene interaction networksJ Biomed Semantics. 2017:12. DOI: 10.1186/s13326-017-0122-4. PMID: 28288685. PMCID: PMC5348867.

Hur J, Özgür A, He Y. The Interaction Network Ontology-supported modeling and mining of complex interactions represented with multiple keywords in biomedical literatureBioData Mining. 2016 Dec 19;9:41. PMID: 28031747. PMCID: PMC5168857

Ozgur A, Hur J, Xiang Z, Ong E, Radev D, He Y. Ignet: A centrality and INO-based web system for analyzing and visualizing literature-mined networks. August 1-2, 2016, joint session ICBO+BioCreative, at the International Conference on Biomedical Ontologies (ICBO-2016) and BioCreative 2016, August 1-4, 2016, Oregon State University, Corvallis, OR, USA. 2-page proceeding paper.

Karadeniz İ, Hur J*, He Y*, Ozgur A*. Literature mining and ontology based analysis of host-Brucella gene-gene interaction networkFront. Microbiol. 2015 Dec 9; 6:1386. PMID: 26696993. PMCID: PMC4673313.

Hur J, Özgür A, Xiang Z, He Y. Development and application of an Interaction Network Ontology for literature mining of vaccine-associated gene-gene interactionsJournal of Biomedical Semantics. 2015, 6:2. doi:10.1186/2041-1480-6-2. PMID: 25785184. PMCID: PMC4362819.

Y Zhang, C Tao, Y He, P Kanjamala, H Liu. Network-based analysis of vaccine-related associations reveals consistent knowledge with the vaccine ontology. Journal of Biomedical Semantics 2013, 4:33  doi:10.1186/2041-1480-4-33. PMID: 24209834.

Xiang Z, Qin T, Qin Z, He Y. A genome-wide MeSH-based literature mining system predicts implicit gene-to-gene relationships and networksBMC Systems Biology. 2013, 7(Suppl 3):S9. PMID: 24555475. PMCID: PMC3852244.

Hur J, Özgür A, Xiang Z, He Y. Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining. Journal of Biomedical Semantics. 2012, 3:18. PMID: 23256563. PMCID: PMC3599673.

Ozgur A, Xiang Z, Radev D, He Y. Mining of vaccine-associated IFN-γ gene interaction networks using the Vaccine Ontology. Journal of Biomedical Semantics. 2011, 2(Suppl 2):S8. PMID: 21624163. PMCID: PMC3102897.

Hur J, Xiang Z, Feldman EL, He Y. Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network. BMC Immunology. 12(1):49 2011 Aug 26. PMID: 21871085.

 


Ontology-based modeling:

Lin Y, Xiang Z, and He Y. Ontology-based representation and analysis of host-Brucella interactions. J Biomed Semantics. 2015, 6:37. DOI: 10.1186/s13326-015-0036-y. PMID: 26445639. PMCID: PMC4594885.

Brinkman RR, Courtot M, Derom D, Fostel JM, He Y, Lord P, Malone J, Parkinson H, Peters B, Rocca-Serra P, Ruttenberg A, Sansone S, Soldatova LN, Stoeckert Jr. CJ, Turner J, Zheng J, the OBI consortium. Modeling biomedical experimental processes with OBI. Journal of Biomedical Semantics. 2010, 1(Suppl 1):S7. [PMID: 20626927]

Sarntivijai S, Zhang S, Jagannathan DG, Zaman S, Burkhart KK, Omenn GS, He Y, Athey BD, Abernethy DR. Linking MedDRA-coded clinical phenotypes to biological mechanisms by the Ontology of Adverse Events: A pilot study on Tyrosine Kinase Inhibitors (TKIs). Drug Safety. 2016. pp 1-11. First online: 22 March 2016. DOI: 10.1007/s40264-016-0414-0. PMID: 27003817. PMCID: PMC4933310.

 


Ontoanimal ontology tool development based on the VIOLIN R01 grant support:

Ontobee: http://www.ontobee.org:

Ong E, Xiang Z, Zhao B, Liu Y, Lin Y, Zheng J, Mungall C, Courtot M, Ruttenberg A, He Y. Ontobee: A linked ontology data server to support ontology term 
dereferencing, linkage, query, and integration
Nucleic Acid Research. 2017 Jan 4;45(D1):D347-D352. PMID: 27733503. PMCID: PMC5210626.

Xiang Z, Mungall C, Ruttenberg A, He Y. Ontobee: A Linked Data Server and Browser for Ontology Terms. Proceedings of the 2nd International Conference on Biomedical Ontologies (ICBO), Buffalo, NY, USA, July 28-30, 2011. Pages 279-281. [http://ceur-ws.org/Vol-833/paper48.pdf]

Ontofox: http://ontofox.hegroup.org:

Xiang Z, Courtot M, Brinkman RR, Ruttenberg A, He Y. OntoFox: web-based support for ontology reuse. BMC Research Notes. 2010, 3:175. [PMID: 20569493]

Ontodog: http://ontodog.hegroup.org:

Zheng J, Xiang Z, Stoeckert Jr. CJ, He Y. Ontodog: a web-based ontology community view generation toolBioinformatics. 2014, 30(9):1340-2. doi: 10.1093/bioinformatics/btu008. [PDF] PMID: 24413522. PMCID: PMC3998133.

Ontorat: http://ontorat.hegroup.org:

Xiang Z, Zheng J, Lin Y, He Y. Ontorat: Automatic generation of new ontology terms, annotations, and axioms based on ontology design patternsJournal of Biomedical Semantics. 2015, 6:4  doi:10.1186/2041-1480-6-4. PMID: 25785185. PMCID: PMC4362828.

Ontobull: http://ontobull.hegroup.org, and BFOConvert:

Edison Ong, Zuoshuang Xiang, Jie Zheng, Barry Smith, Yongqun He. Ontobull and BFOConvert: Web-based Programs to Support Automatic Ontology Conversion. August 1-2, 2016, joint session ICBO+BioCreative, at the International Conference on Biomedical Ontologies (ICBO-2016) and BioCreative 2016, August 1-4, 2016, Oregon State University, Corvallis, OR, USA. 2-page proceeding paper (SOftware Demo).

Ontokiwi and Ontokiwi-based Ontobedia:

Ong E, He Y. Community-based ontology development, annotation and discussion with MediaWiki extension Ontokiwi and Ontokiwi-based Ontobedia. AMIA Jt Summits Transl Sci Proc. 2016 Jul 20;2016:65-74. eCollection 2016. PMID: 27570653. PMCID: PMC5001762.

 

Proposed eXtensible ontology development (XOD) principles:

He Y, Xiang Z, Zheng J, Lin Y, Overton JA, Ong E. The eXtensible ontology development (XOD) principles and tool implementation to support ontology interoperability. J Biomed Semantics. 2018 Jan 12;9(1):3. PMID: 29329592. PMCID: PMC5765662.

 


VO-based Annotation and Curation:

He Y, Xiang Z. Bioinformatics analysis of Brucella vaccines and vaccine targets using VIOLIN. Immunome Res. 2010 Sep 27;6 Suppl 1:S5. [NAR] [PubMed] [PDF].
(Note: use VO to study Brucella vaccines)

Yang B, Sayers S, Xiang Z, He Y. Protegen: a web-based protective antigen database and analysis system. Nucleic Acids Research. 2010. 2010 Oct 19. [Epub ahead of print]. [PMID: 20959289]
(Note: all protective antigens in Protegen are annotated in VO)

Sayers S, Ulysse G, Xiang Z, and He Y. Vaxjo: a web-based vaccine adjuvant database and its application for analysis of vaccine adjuvants and their uses in vaccine development. Journal of Biomedicine and Biotechnology. In press.
(Note: all vaccine adjuvants in Vaxjo are annotated in VO)

 


Vaccine adverse events:

Sarntivijai S, Xiang Z, Shedden KA, Markel H, Omenn GS, Athey BD, and He Y. Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines. PLoS ONE. 2012, 7(11): e49941. doi:10.1371/journal.pone.0049941.

Marcos E , He Y. The Ontology of Vaccine Adverse Events (OVAE) and its usage in representing and analyzing vaccine adverse events. Workshop “Vaccine and Drug Ontology Studies (VDOS 2013)". International Conference on Biomedical Ontologies (ICBO), Montreal, Qc, Canada. July 7, 2013 . Full-length proceeding paper. [http://ceur-ws.org/Vol-1061/Paper9_vdos2013.pdf]

Marcos E , Zhao B, He Y. The ontology of vaccine adverse events (OVAE) and its usage in representing and analyzing adverse events associated with US-licensed human vaccines. Journal of Biomedical Semantics. 2013 Nov 26;4(1):40. PMID: 24279920.

Xie J, Zhao L, Zhou S, He Y. Statistical and ontological analysis of adverse events associated with monovalent and combination vaccines against hepatitis A and B diseasesScientific Reports. 2016. 6:3418. PMID: 27694888. PMCID: PMC5046117

Xie J, Codd C, Mo K, He Y. Differential adverse event profiles associated with BCG as a preventive tuberculosis vaccine or therapeutic bladder cancer vaccine identified by comparative ontology-based VAERS and literature meta-analysis. PLoS ONE. 2016 Oct 17;11(10):e0164792. PMID: 27749923. PMCID: PMC5066964.

 


Pathogen use case studies using VIOLIN or supported by the VIOLIN R01 funding:

Brucella use case:

He Y, Xiang Z. Bioinformatics analysis of Brucella vaccines and vaccine targets using VIOLIN. Immunome Res. 2010 Sep 27;6 Suppl 1:S5. [NAR] [PubMed] [PDF].

He Y. Analyses of Brucella pathogenesis, host immunity, and vaccine targets using systems biology and bioinformatics. Frontiers in Cellular and Infection Microbiology. 2012. 2:2. doi: 10.3389/fcimb.2012.00002.

Xie J, Wang J, Li Z, Wang W, Pang Y, and He Y. Ontology-based meta-analysis of animal and human adverse events associated with licensed brucellosis vaccinesFrontiers in Pharmacology. 2018 May 15;9:503. PMID: 29867505. PMCID: PMC5962797.

Other use cases:

Wang Y, Wen Z, Pan X, Briles DE, He Y, Zhang JR. Novel immunoprotective proteins of Streptococcus pneumoniae identified by opsonophagocytosis killing screen. Infect Immun. 2018 Jun 11. pii: IAI.00423-18. PMID: 29891544.

Hur J, Ozgur A, He Y. Ontology-based literature mining of E. coli vaccine-associated gene interaction networksJ Biomed Semantics. 2017:12. DOI: 10.1186/s13326-017-0122-4. PMID: 28288685. PMCID: PMC5348867.

Ni Z, Chen Y, Ong E, He Y. Antibiotic resistance determinants-focused Acinetobacter baumannii vaccine design using reverse vaccinologyInternational Journal of Molecular Sciences. 2017, 18(2), 458. PMID: 28230771. PMCID: PMC5343991.

Lopera-Madrid J, Osorio JE, He Y, Xiang Z, Adams LG, Laughlin RC, Mwangi W, Subramanya S, Neilan J, Brake D, Burrage TG, Brown WC, Clavijo A, Bounpheng MA. Safety and immunogenicity of mammalian cell derived and modified-vaccinia Ankara vectored African swine fever subunit antigens in swineVeterinary Immunology and Immunopathology. 2017. DOI: 10.1016/j.vetimm.2017.01.004. PMID: 28241999.

McNamara L, He Y, Yang Z. Using epitope predictions to evaluate efficacy and population coverage of the Mtb72f vaccine for tuberculosis. BMC Immunology. 2010 Mar 30;11(1):18. [PMID: 20353587] [Journal Link]

 


Papers related to Community Participation:

Tao C, He Y, Arabandi S. Vaccine and Drug Ontology Studies (VDOS 2014)Journal of Biomedical Semantics..2016, 7:6. DOI: 10.1186/s13326-015-0039-8. PMID: 26918107.

Tao C, He Y, Arabandi S. A 2013 Workshop: Vaccine and Drug Ontology Studies (VDOS 2013)Journal of Biomedical Semantics. 2014 Mar 20;5(1):16. doi: 10.1186/2041-1480-5-16. PMID: 24650607. PMCID: PMC3994568. (Note: check: http://www2.unb.ca/csas/data/ws/semantic-trilogy-workshops/proceedings.html)

De Groot AS, De Groot P, He Y. ICoVax 2013: The 3rd ISV Pre-conference Computational Vaccinology Workshop. BMC Bioinformatics. 2014. In press. (Note: check: http://www.violinet.org/icovax2013)

He Y, Cao Z, De Groot AS, Brusic V, Schönbach C, Petrovsky N. Computational vaccinology and the ICoVax 2012 workshop. BMC Bioinformatics. 2013, 14(Suppl 4):I1 (8 March 2013). PMID: 23514034; PMCID: PMC3599086. (Note: check: http://www.violinet.org/icovax2012)

He Y, Toldo L, Burns G, Tao C, Abernethy DR. A 2012 Workshop: Vaccine and Drug Ontology in the Study of Mechanism and Effect (VDOSME 2012). Journal of Biomedical Semantics 2012, 3:12. PMID: 23249650. PMCID: PMC3554582. (Note: check: http://kr-med.org/icbofois2012/vdosme/)

 


The OneNet Theory of Life and vaccine research:

He Y. Ontology-based vaccine and drug adverse event representation and theory-guided systematic causal network analysis towards integrative pharmacovigilance research. Current Pharmacology Reports. 2016, Volume 2, Issue 3, pp 113-128. DOI: 10.1007/s40495-016-0055-0.

He Y. Ontology-supported research on vaccine efficacy, safety, and integrative biological networksExpert Reviews in Vaccines. 2014 Jul;13(7):825-41. doi: 10.1586/14760584.2014.923762. Epub 2014 Jun 7. PMID: 24909153. PMCID: PMC4815432.

 


Reviews and book chapters:

He Y. Genome-based computational vaccine discovery by reverse vaccinology (Chapter 5); in book: Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines, edited by Darren R. Flower, Yvonne Perrie. Publisher: Springer, New York, 2013. ISBN-13: 978-1461450696. ISBN 978-1-4614-5070-2 (eBook). Links in: Google eBook, and Amazon book.

He Y, Xiang Z. Databases and in silico tools for vaccine design. Methods Mol Biol. 2013;993:115-27. doi: 10.1007/978-1-62703-342-8_8. PMID: 23568467. [Note: this is Chapter 8 in book: In Silico Models for Drug Discovery, Editor: Sandhya Kortagere.]

He Y. Analyses of Brucella pathogenesis, host immunity, and vaccine targets using systems biology and bioinformatics. Frontiers in Cellular and Infection Microbiology. 2012. 2:2. doi: 10.3389/fcimb.2012.00002.

 


Special Feature Report on Dr. He and He group's vaccine informatics research by International Innovation:

Yongqun He: 'Analysing multidisciplinary vaccine mechanisms'. In research topic: The Mechanics of Health, International Innovation, July 2013, (Research Media, pp 41-43) ISSN 2041-4552.
(Note: International Innovation is the leading global dissemination resource for the wider scientific, technology and research communities, dedicated to disseminating the latest science, research and technological innovations on a global level. More information and a complimentary subscription offer to the publication can be found at: www.researchmedia.eu).

 

Note: More Hegroup publications can be found here: http://www.hegroup.org/publications.html (all areas).