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VIOLIN Statistics

Currently, VIOLIN includes 3448 vaccines for 209 pathogens or non-infectious diseases (e.g., cancer). The vaccines annotated in VIOLIN include licensed vaccines, vaccines being tested in clinical trials, and vaccines that have been studied in research and experimentally verified effective in at least one laboratory animal model. See detailed curated data here:

Index Pathogen Name Disease No. of Vaccines No. of Licensed Vaccines No. of Vaccine-related
pathogen genes
No. of Vaccine-related
host genes
No. of References
Bacteria
G+ Bacteria
1 Bacillus anthracis Anthrax 28 4 17 0 47
2 Clostridium botulinum Botulism 18 8 7 0 21
3 Clostridium perfringens Food poisioning, Gas gangrene 6 6 0 0 0
4 Clostridium tetani Tetanus 60 57 2 0 17
5 Corynebacterium diphtheriae Diphtheria 22 22 1 0 16
6 Erysipelothrix rhusiopathiae Erysipelas 29 28 1 0 3
7 Listeria monocytogenes Listeriosis 4 0 4 1 8
8 Mycobacterium avium 2 0 1 4 3
9 Mycobacterium marinum 1 0 1 0 2
10 Mycobacterium tuberculosis Tuberculosis 47 3 43 39 80
11 Staphylococcus aureus Staph infections 8 0 7 2 11
12 Streptococcus agalactiae Group B streptococcus (GBS) infection 4 0 4 0 7
13 Streptococcus equi Strangles (also equine distemper) 5 2 7 1 9
14 Streptococcus pneumoniae Pneumonia 18 6 13 0 26
15 Streptococcus pyogenes Group A streptococcal infections, Strep throat, Scarlet fever 7 0 5 2 9
16 Streptococcus suis 1 1 0 0 1
G- Bacteria
17 Actinobacillus pleuropneumoniae porcine pleuropneumonia 15 2 16 2 19
18 Aeromonas hydrophila 2 0 1 0 3
19 Aeromonas salmonicida Furunculosis, Bald sea urchin disease 3 2 3 0 6
20 Bordetella avium Bordetellosis 2 2 0 0 2
21 Bordetella bronchiseptica Infectious bronchitis, kennel cough 10 6 5 5 7
22 Bordetella pertussis Whooping Cough 28 16 14 0 27
23 Borrelia burgdorferi Lyme Disease 14 6 5 0 6
24 Brucella spp. Brucellosis 60 7 46 9 119
25 Burkholderia pseudomallei Melioidosis 7 0 8 1 7
26 Campylobacter fetus bovine venereal campylobacteriosis (BVC) 17 17 0 0 0
27 Campylobacter jejuni Campylobacterosis 11 0 10 2 32
28 Chlamydia muridarum 10 0 10 3 7
29 Chlamydia trachomatis Chlamydia 4 1 1 0 6
30 Chlamydophila abortus Abortion and fetal death 10 1 10 1 5
31 Chlamydophila pneumoniae Pneumonia 6 0 6 2 6
32 Chlamydophila psittaci Respiratory psittacosis, avian chlamydiosis 18 17 3 0 4
33 Coxiella burnetii Q fever 6 0 2 1 30
34 Edwardsiella ictaluri Enteric septicemia of channel catfish (ESC) 2 1 1 1 3
35 Edwardsiella tarda 9 0 8 0 6
36 Escherichia coli Hemorrhagic colitis 42 14 25 4 42
37 Flavobacterium columnare Columnaris 1 1 0 0 1
38 Francisella tularensis Tularemia 25 1 24 15 31
39 Haemophilus influenzae Meningitis 30 11 15 3 59
40 Haemophilus parasuis Glasser's disease 4 3 1 0 2
41 Haemophilus somnus 24 24 0 0 1
42 Helicobacter pylori Ulcers 12 0 9 0 13
43 Lawsonia intracellularis Lawsonia intracellularis infection 4 4 0 0 3
44 Leptospira spp. Leptospirosis 132 130 2 0 3
45 Mannheimia haemolytica Bovine Respiratory Disease 16 15 1 0 2
46 Mycoplasma gallisepticum Chronic respiratory disease 14 12 2 1 5
47 Mycoplasma hyopneumoniae Porcine Enzootic Pneumonia 11 10 1 0 2
48 Mycoplasma synoviae Respiratory tract disease and synovitis 1 1 0 0 1
49 Neisseria meningitidis Meningitis 18 9 24 0 19
50 Pasteurella multocida Pasteurellosis, fowl cholera 21 17 4 2 5
51 Piscirickettsia salmonis Salmon Rickettsial Disease, Piscirickettsiosis 1 1 0 0 1
52 Porphyromonas gulae Canine periodontitis 1 1 0 0 1
53 Pseudomonas aeruginosa Pseudomonas aeruginosa infection 11 4 4 0 7
54 Rickettsia spp Spotted Fever, Typhus 2 0 3 1 6
55 Riemerella anatipestifer New duck disease, Infectious serositis, Pasteurella anatipestifer infection 1 1 0 0 1
56 Salmonella spp. Salmonellosis 62 19 61 13 57
57 Shigella Shigellosis 24 2 14 4 25
58 Treponema pallidum Syphilis 3 0 3 0 6
59 Vibrio anguillarum (Listonella anguillarum) Vibrosis 2 2 1 0 2
60 Vibrio cholerae Cholera 4 2 4 2 6
61 Yersinia enterocolitica Yersiniosis 5 0 5 2 6
62 Yersinia pestis Plague 29 2 36 1 57
63 Yersinia pseudotuberculosis Yersiniosis 1 0 2 0 4
64 Yersinia ruckeri Enteric redmouth disease 2 1 1 0 3
Viruses
65 Adenovirus Respiratory infection 1 1 0 0 2
66 African horse sickness virus 2 0 0 0 2
67 African Swine Fever Virus African Swine Fever 2 0 1 0 4
68 Avian Encephalomyelitis Virus Avian Encephalomyelitis 13 13 0 0 3
69 Avian Paramyxovirus 4 3 0 0 2
70 Avian pneumovirus Turkey rhinotracheitis, Avian rhinotracheitis, Swollen head syndrome 2 1 1 0 1
71 Avian Polyomavirus Papovavirus, Budgerigar fledgling disease, Psittacine polyomavirus 1 1 0 0 1
72 Avian Reovirus Viral Arthritis, Pale Bird Syndrome, Tenosynovitis 36 36 0 0 1
73 Bluetongue virus Bluetongue disesase 6 1 0 0 6
74 Borna disease virus 1 0 0 0 1
75 Bovine coronavirus 5 5 0 0 0
76 Bovine herpesvirus 1 Infectious bovine rhinotracheitis 159 146 9 0 22
77 Bovine Leukemia virus 1 0 1 0 3
78 Bovine papillomavirus Warts 1 1 0 0 0
79 Bovine Parainfluenza 3 Virus (BPIV-3) 108 108 0 0 1
80 Bovine Respiratory Syncytial Virus Respiratory Disease 55 53 2 0 4
81 Bovine viral diarrhea virus 1 Bovine viral Diarrhea (BVD) 129 128 0 0 2
82 Bovine viral diarrhea virus 2 Bovine viral diarrhea 1 0 1 0 3
83 Canarypox virus Canary Pox 1 1 0 0 0
84 Canine adenovirus type 1 Fox Encephalitis, Infectious Canine Hepatitis 3 3 0 0 1
85 Canine Adenovirus Type 2 57 57 0 0 1
86 Canine coronavirus Intestinal disease 41 41 0 0 2
87 Canine distemper virus Canine distemper 79 76 2 0 4
88 Canine parainfluenza virus 56 56 0 0 1
89 Canine parvovirus Canine parvovirus infection 68 66 2 1 3
90 Caprine herpesvirus type 1 (CpHV-1) 1 0 0 0 1
91 Chicken Anemia Virus Chicken infectious anemia, Blue wing disease, Anemia dermatitis syndrome, Hemorrhagic aplastic anemi 3 3 0 0 1
92 chikungunya virus 1 1 0 0 1
93 Classical swine fever virus Classical swine fever, hog cholera 14 4 7 0 15
94 Corynebacterium pseudotuberculosis 1 0 0 0 1
95 Crimean-Congo Haemorrhagic Fever (CCHF) 1 0 0 0 1
96 Dengue Virus Dengue Fever 17 0 11 0 18
97 Duck enteritis virus Duck Plague 1 1 0 0 1
98 Duck hepatitis virus 1 Duck virus hepatitis (DVH) 2 1 1 0 2
99 Eastern Equine Encephalitis Virus Encephalitis 38 38 0 0 1
100 Ebola virus Ebola hemorrhagic fever 29 2 17 0 29
101 Equid herpesvirus Equine Rhinopneumonitis 24 20 3 0 3
102 Equine arteritis virus Equine arteritis 1 1 0 0 0
103 Equine rotavirus Rotaviral Diarrhea 1 1 0 0 1
104 Feline calicivirus Feline Respiratory Infections 35 34 0 0 2
105 Feline herpesvirus 1 Feline viral rhinotracheitis 34 33 1 0 2
106 Feline immunodeficiency virus Feline AIDS 6 3 2 0 3
107 Feline infectious peritonitis virus Feline infectious peritonitis (FIP) 3 1 5 0 2
108 Feline leukemia virus Feline leukemia virus infection 18 16 3 0 3
109 Feline panleukopenia virus Feline Distemper 32 32 0 0 2
110 Foot-and-mouth disease virus Foot-and-mouth disease 4 0 8 0 5
111 Fowlpox virus Fowlpox 20 20 0 0 2
112 Gallid herpesvirus 1 Avian infectious laryngotracheitis, Fowl Laryngotracheitis 14 10 5 0 5
113 Hantavirus Hantavirus Pulmonary Syndrome 13 0 11 2 15
114 Hendra virus Hendra virus disease 1 0 1 0 2
115 Hepatitis A virus Hepatitis A 8 8 1 0 9
116 Hepatitis B virus Hepatitis B 20 7 10 0 33
117 Hepatitis C virus Hepatitis C 0 0 1 0 1
118 Hepatitis D virus 1 0 1 0 2
119 Hepatitis E virus Hepatitis E 0 0 1 0 2
120 Herpes simplex virus type 1 and 2 Herpes 29 0 18 1 33
121 Hirame rhabdovirus 3 1 2 0 3
122 Human coxsackievirus 1 0 1 0 2
123 Human cytomegalovirus 2 0 2 0 2
124 Human Immunodeficiency Virus Acquired Immunodeficiency Syndrome (AIDS) 39 9 52 13 103
125 Human metapneumovirus Respiratory tract infection 2 0 2 0 2
126 Human Papillomavirus HPV infection 13 2 5 0 24
127 Human Respiratory Syncytial Virus Respiratory tract disease 4 0 3 0 5
128 Infectious Bronchitis Virus (IBV) Infectious Bronchitis 88 83 3 0 6
129 Infectious Bursal Disease Virus (IBDV) Infectious Bursal Disease 92 86 2 0 3
130 Infectious Hematopoietic Necrosis Virus Infectious hematopoietic necrosis 7 1 3 0 8
131 infectious laryngotracheitis virus 5 1 0 0 4
132 Infectious pancreatic necrosis virus 1 0 2 0 2
133 Infectious salmon anemia virus Infectious Salmon Anemia 1 1 0 0 2
134 Influenza virus Influenza (flu) 188 115 53 102 131
135 Japanese encephalitis virus Japanese encephalitis 13 2 7 1 8
136 Lassa Fever Virus Lassa fever 13 0 3 0 8
137 Lymphocytic choriomeningitis virus Lymphocytic choriomeningitis 1 0 2 0 1
138 Marburg Virus Hemorrhagic fever 18 0 18 0 12
139 Marek's disease virus Marek's disease 53 51 2 0 3
140 Measles virus Measles 14 9 5 1 13
141 Mink enteritis virus Mink Enteritis 10 10 0 0 1
142 Mumps virus Mumps 7 5 1 0 5
143 Murine Cytomegalovirus 2 0 3 0 3
144 Murine leukemia virus 0 0 1 0 1
145 Newcastle disease virus Newcastle disease 100 95 3 0 8
146 Nipah virus Nipah virus disease 4 0 2 0 3
147 Orf Virus Orf disease, Sore mouth (Ovine Ecthyma) 2 2 0 0 1
148 Parainfluenza virus 0 0 2 0 1
149 Pigeonpox virus Pigeon Pox 3 3 0 0 1
150 Poliovirus Polio 13 13 1 0 8
151 Porcine circovirus 2 Postweaning multisystemic wasting syndrome 11 7 1 2 4
152 Porcine parvovirus SMEDI, reproductive failure 19 19 0 0 0
153 Porcine respiratory and reproductive syndrome virus Porcine Reproductive and Respiratory Syndrome (PRRS), Blue-Ear Pig Disease 17 10 6 0 7
154 Porcine rotavirus Diarrhea 2 2 0 0 1
155 Pseudorabies virus Aujeszky's disease 18 6 16 3 19
156 Psittacid herpesvirus 1 Pacheco's Parrot Disease 1 1 0 0 2
157 Rabbit hemorrhagic disease virus Rabbit hemorrhagic disease 3 0 1 0 2
158 Rabies virus Rabies 34 20 6 0 22
159 Reticuloendotheliosis Virus Tumors, wasting syndrome 1 0 3 0 0
160 Rift Valley Fever virus Rift valley fever 3 2 2 0 5
161 rinderpest virus 2 0 0 0 2
162 Rotavirus Gastroenteritis 14 9 8 2 13
163 Rubella virus Rubella 6 6 0 0 4
164 SARS-CoV Severe Acute Respiratory Syndrome (SARS) 5 0 3 0 9
165 Simian Immunodeficiency Virus Simian AIDS 5 1 4 0 10
166 Sindbis virus Encephalitis 1 0 1 0 1
167 Tick-borne Encephalitis Virus (TBEV) Tick-borne Encephalitis 3 1 2 0 3
168 Transmissible gastroenteritis virus Porcine transmissible gastroenteritis 5 5 0 0 0
169 Turkey hemorrhagic enteritis virus Hemorrhagic enteritis 1 1 0 0 1
170 Vaccinia virus 6 0 9 0 6
171 Varicella-zoster virus chickenpox / shingles 7 6 2 0 8
172 Variola virus Smallpox 14 2 17 0 34
173 VEE Virus Venezuelan equine encephalitis 30 15 6 0 44
174 Viral haemorrhagic septicaemia virus 3 0 2 0 3
175 West Nile virus West Nile fever 23 18 3 1 7
176 Western equine encephalomyelitis virus Western equine encephalomyelitis (WEE) 43 38 5 0 5
177 Yellow fever virus Yellow fever 3 1 2 65 10
Parasites
178 Babesia bovis Babesiosis, Texas Cattle Fever 2 0 4 0 6
179 Babesia canis Piroplasmosis 1 1 0 0 2
180 Cryptosporidium parvum Cryptosporidiosis 2 0 2 2 3
181 Eimeria maxima Coccidiosis 4 1 2 2 4
182 Eimeria spp. Coccidiosis 11 8 1 0 4
183 Eimeria tenella Hemorrhagic cecal coccidiosis 7 0 5 0 7
184 Entamoeba histolytica Amoebiasis 4 0 4 0 5
185 Giardia duodenalis Giardiasis (Beaver fever) 3 2 1 0 4
186 Leishmania amazonensis Leishmaniasis 4 0 5 0 5
187 Leishmania donovani Visceral leishmaniasis 16 1 13 4 16
188 Leishmania infantum Infantile visceral leishmaniasis 7 0 6 1 6
189 Leishmania major Cutaneous leishmaniasis 10 1 11 0 13
190 Neospora caninum Neosporosis 12 2 8 0 11
191 Plasmodium spp. Malaria 44 1 44 0 119
192 Sarcocystis neurona Equine protozoal myeloencephalitis 2 1 1 0 3
193 Schistosoma japonicum Schistosomiasis 9 0 5 0 5
194 Schistosoma mansoni Schistosomiasis 4 0 4 0 4
195 Theileria annulata Theileriosis 3 0 2 0 5
196 Theileria parva East Coast Fever 2 0 1 0 3
197 Toxoplasma gondii Toxoplasmosis 15 0 19 5 17
198 Trichomonas foetus 2 2 0 0 1
199 Trypanosoma brucei African trypanosomiasis (African Sleeping Sickness) 2 0 2 0 3
200 Trypanosoma cruzi Chagas disease 14 0 16 0 17
Fungi
201 Coccidioides spp. Coccidioidomycosis (California disease, Desert rheumatism, San Joaquin valley fever, and Valley fev 4 0 9 0 9
Other diseases
202 Allergy Allergy 1 0 16 0 18
203 Arthritis 4 0 4 6 6
204 Atherosclerosis Atherosclerosis, arteriosclerotic vascular disease (ASVD) 2 0 0 0 3
205 Cancer Cancer 71 3 74 0 222
206 Diabetes Diabetes 4 0 5 0 9
207 Experimental autoimmune encephalomyelitis Experimental autoimmune encephalomyelitis (EAE) 1 0 3 0 11
208 Experimental autoimmune uveitis Experimental autoimmune uveitis 1 0 2 0 2
209 Ricin toxin of Ricinus communis Ricin poisoning 0 0 1 0 2
Total 209 3448 2217 1179 338 2335

Also, the VIOLIN database contains 24,345 abstracts and 10,317 full text PDF documents for 24,345 vaccine-related papers downloaded from PubMed.

Note: This table is automatically updated to reflect updated statistics in the VIOLIN database.