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VIOLIN Statistics

Currently, VIOLIN includes 3251 vaccines for 200 pathogens or non-infectious diseases (e.g., cancer). The vaccines annotated in VIOLIN include licensed vaccines, vaccines being tested in clinical trials, and vaccines that have been studied in research and experimentally verified effective in at least one laboratory animal model. See detailed curated data here:

Index Pathogen Name Disease No. of Vaccines No. of Licensed Vaccines No. of Vaccine-related
pathogen genes
No. of Vaccine-related
host genes
No. of References
Bacteria
G+ Bacteria
1 Bacillus anthracis Anthrax 26 4 16 0 45
2 Clostridium botulinum Botulism 18 8 7 0 21
3 Clostridium perfringens Food poisioning, Gas gangrene 6 6 0 0 0
4 Clostridium tetani Tetanus 60 57 2 0 17
5 Corynebacterium diphtheriae Diphtheria 22 22 1 0 16
6 Erysipelothrix rhusiopathiae Erysipelas 29 28 1 0 3
7 Listeria monocytogenes Listeriosis 4 0 4 1 8
8 Mycobacterium avium 2 0 1 4 3
9 Mycobacterium marinum 1 0 1 0 2
10 Mycobacterium tuberculosis Tuberculosis 43 2 42 39 79
11 Staphylococcus aureus Staph infections 8 0 7 2 11
12 Streptococcus agalactiae Group B streptococcus (GBS) infection 4 0 4 0 7
13 Streptococcus equi Strangles (also equine distemper) 5 2 7 1 9
14 Streptococcus pneumoniae Pneumonia 17 6 13 0 25
15 Streptococcus pyogenes Group A streptococcal infections, Strep throat, Scarlet fever 6 0 5 2 8
G- Bacteria
16 Actinobacillus pleuropneumoniae porcine pleuropneumonia 11 2 16 2 16
17 Aeromonas hydrophila 1 0 1 0 2
18 Aeromonas salmonicida Furunculosis, Bald sea urchin disease 3 2 3 0 6
19 Bordetella avium Bordetellosis 2 2 0 0 2
20 Bordetella bronchiseptica Infectious bronchitis, kennel cough 10 6 5 5 7
21 Bordetella pertussis Whooping Cough 24 15 14 0 23
22 Borrelia burgdorferi Lyme Disease 14 6 5 0 6
23 Brucella spp. Brucellosis 60 7 46 9 119
24 Burkholderia pseudomallei Melioidosis 7 0 8 1 7
25 Campylobacter fetus bovine venereal campylobacteriosis (BVC) 17 17 0 0 0
26 Campylobacter jejuni Campylobacterosis 11 0 10 2 32
27 Chlamydia muridarum 10 0 10 3 7
28 Chlamydia trachomatis Chlamydia 2 0 1 0 3
29 Chlamydophila abortus Abortion and fetal death 10 1 10 1 5
30 Chlamydophila pneumoniae Pneumonia 6 0 6 2 6
31 Chlamydophila psittaci Respiratory psittacosis, avian chlamydiosis 18 17 3 0 4
32 Coxiella burnetii Q fever 6 0 2 1 30
33 Edwardsiella ictaluri Enteric septicemia of channel catfish (ESC) 2 1 1 1 3
34 Edwardsiella tarda 7 0 8 0 5
35 Escherichia coli Hemorrhagic colitis 40 14 25 4 42
36 Flavobacterium columnare Columnaris 1 1 0 0 1
37 Francisella tularensis Tularemia 25 1 24 15 31
38 Haemophilus influenzae Meningitis 30 11 15 3 59
39 Haemophilus parasuis Glasser's disease 4 3 1 0 2
40 Haemophilus somnus 24 24 0 0 1
41 Helicobacter pylori Ulcers 10 0 9 0 11
42 Lawsonia intracellularis Lawsonia intracellularis infection 4 4 0 0 3
43 Leptospira spp. Leptospirosis 132 130 2 0 3
44 Mannheimia haemolytica Bovine Respiratory Disease 16 15 1 0 2
45 Mycoplasma gallisepticum Chronic respiratory disease 14 12 2 1 5
46 Mycoplasma hyopneumoniae Porcine Enzootic Pneumonia 10 10 1 0 2
47 Mycoplasma synoviae Respiratory tract disease and synovitis 1 1 0 0 1
48 Neisseria meningitidis Meningitis 18 9 24 0 19
49 Pasteurella multocida Pasteurellosis, fowl cholera 21 17 4 2 5
50 Piscirickettsia salmonis Salmon Rickettsial Disease, Piscirickettsiosis 1 1 0 0 1
51 Porphyromonas gulae Canine periodontitis 1 1 0 0 1
52 Pseudomonas aeruginosa Pseudomonas aeruginosa infection 10 4 4 0 7
53 Rickettsia spp Spotted Fever, Typhus 2 0 3 1 6
54 Riemerella anatipestifer New duck disease, Infectious serositis, Pasteurella anatipestifer infection 1 1 0 0 1
55 Salmonella spp. Salmonellosis 62 19 61 13 57
56 Shigella Shigellosis 22 2 14 4 25
57 Treponema pallidum Syphilis 3 0 3 0 6
58 Vibrio anguillarum (Listonella anguillarum) Vibrosis 2 2 1 0 2
59 Vibrio cholerae Cholera 4 2 4 2 6
60 Yersinia enterocolitica Yersiniosis 5 0 5 2 6
61 Yersinia pestis Plague 27 2 36 1 57
62 Yersinia pseudotuberculosis Yersiniosis 1 0 2 0 4
63 Yersinia ruckeri Enteric redmouth disease 2 1 1 0 3
Viruses
64 Adenovirus Respiratory infection 1 1 0 0 2
65 African Swine Fever Virus African Swine Fever 1 0 1 0 2
66 Avian Encephalomyelitis Virus Avian Encephalomyelitis 13 13 0 0 3
67 Avian Paramyxovirus 4 3 0 0 2
68 Avian pneumovirus Turkey rhinotracheitis, Avian rhinotracheitis, Swollen head syndrome 2 1 1 0 1
69 Avian Polyomavirus Papovavirus, Budgerigar fledgling disease, Psittacine polyomavirus 1 1 0 0 1
70 Avian Reovirus Viral Arthritis, Pale Bird Syndrome, Tenosynovitis 36 36 0 0 1
71 Bluetongue virus Bluetongue disesase 1 1 0 0 2
72 Bovine coronavirus 5 5 0 0 0
73 Bovine herpesvirus 1 Infectious bovine rhinotracheitis 159 146 9 0 22
74 Bovine Leukemia virus 1 0 1 0 3
75 Bovine papillomavirus Warts 1 1 0 0 0
76 Bovine Parainfluenza 3 Virus (BPIV-3) 108 108 0 0 1
77 Bovine Respiratory Syncytial Virus Respiratory Disease 55 53 2 0 4
78 Bovine viral diarrhea virus 1 Bovine viral Diarrhea (BVD) 129 128 0 0 2
79 Bovine viral diarrhea virus 2 Bovine viral diarrhea 1 0 1 0 3
80 Canarypox virus Canary Pox 1 1 0 0 0
81 Canine adenovirus type 1 Fox Encephalitis, Infectious Canine Hepatitis 3 3 0 0 1
82 Canine Adenovirus Type 2 57 57 0 0 1
83 Canine coronavirus Intestinal disease 41 41 0 0 2
84 Canine distemper virus Canine distemper 77 75 2 0 3
85 Canine parainfluenza virus 56 56 0 0 1
86 Canine parvovirus Canine parvovirus infection 68 66 2 1 3
87 Chicken Anemia Virus Chicken infectious anemia, Blue wing disease, Anemia dermatitis syndrome, Hemorrhagic aplastic anemi 3 3 0 0 1
88 Classical swine fever virus Classical swine fever, hog cholera 11 3 7 0 11
89 Dengue Virus Dengue Fever 16 0 9 0 15
90 Duck enteritis virus Duck Plague 1 1 0 0 1
91 Duck hepatitis virus 1 Duck virus hepatitis (DVH) 2 1 1 0 2
92 Eastern Equine Encephalitis Virus Encephalitis 38 38 0 0 1
93 Ebola virus Ebola hemorrhagic fever 20 0 16 0 23
94 Equid herpesvirus Equine Rhinopneumonitis 23 20 3 0 3
95 Equine arteritis virus Equine arteritis 1 1 0 0 0
96 Equine rotavirus Rotaviral Diarrhea 1 1 0 0 1
97 Feline calicivirus Feline Respiratory Infections 34 34 0 0 1
98 Feline herpesvirus 1 Feline viral rhinotracheitis 34 33 1 0 2
99 Feline immunodeficiency virus Feline AIDS 6 3 2 0 3
100 Feline infectious peritonitis virus Feline infectious peritonitis (FIP) 3 1 5 0 2
101 Feline leukemia virus Feline leukemia virus infection 17 16 3 0 3
102 Feline panleukopenia virus Feline Distemper 32 32 0 0 2
103 Foot-and-mouth disease virus Foot-and-mouth disease 4 0 8 0 5
104 Fowlpox virus Fowlpox 20 20 0 0 2
105 Gallid herpesvirus 1 Avian infectious laryngotracheitis, Fowl Laryngotracheitis 14 10 5 0 5
106 Hantavirus Hantavirus Pulmonary Syndrome 12 0 11 2 14
107 Hendra virus Hendra virus disease 1 0 1 0 2
108 Hepatitis A virus Hepatitis A 8 8 1 0 9
109 Hepatitis B virus Hepatitis B 20 7 10 0 33
110 Hepatitis C virus Hepatitis C 0 0 1 0 1
111 Hepatitis D virus 1 0 1 0 2
112 Hepatitis E virus Hepatitis E 0 0 1 0 2
113 Herpes simplex virus type 1 and 2 Herpes 27 0 18 1 33
114 Hirame rhabdovirus 3 1 2 0 3
115 Human coxsackievirus 1 0 1 0 2
116 Human cytomegalovirus 2 0 2 0 2
117 Human Immunodeficiency Virus Acquired Immunodeficiency Syndrome (AIDS) 28 0 52 13 94
118 Human metapneumovirus Respiratory tract infection 2 0 2 0 2
119 Human Papillomavirus HPV infection 12 2 5 0 10
120 Human Respiratory Syncytial Virus Respiratory tract disease 3 0 3 0 4
121 Infectious Bronchitis Virus (IBV) Infectious Bronchitis 87 83 3 0 6
122 Infectious Bursal Disease Virus (IBDV) Infectious Bursal Disease 87 84 2 0 3
123 Infectious Hematopoietic Necrosis Virus Infectious hematopoietic necrosis 7 1 3 0 8
124 Infectious pancreatic necrosis virus 1 0 2 0 2
125 Infectious salmon anemia virus Infectious Salmon Anemia 1 1 0 0 2
126 Influenza virus Influenza (flu) 153 89 52 102 101
127 Japanese encephalitis virus Japanese encephalitis 10 2 7 1 8
128 Lassa Fever Virus Lassa fever 13 0 3 0 8
129 Lymphocytic choriomeningitis virus Lymphocytic choriomeningitis 1 0 2 0 1
130 Marburg Virus Hemorrhagic fever 16 0 18 0 12
131 Marek's disease virus Marek's disease 53 51 2 0 3
132 Measles virus Measles 13 9 5 1 13
133 Mink enteritis virus Mink Enteritis 10 10 0 0 1
134 Mumps virus Mumps 6 5 1 0 5
135 Murine Cytomegalovirus 2 0 3 0 3
136 Murine leukemia virus 0 0 1 0 1
137 Newcastle disease virus Newcastle disease 97 95 3 0 4
138 Nipah virus Nipah virus disease 1 0 2 0 3
139 Orf Virus Orf disease, Sore mouth (Ovine Ecthyma) 2 2 0 0 1
140 Parainfluenza virus 0 0 2 0 1
141 Pigeonpox virus Pigeon Pox 3 3 0 0 1
142 Poliovirus Polio 13 13 1 0 8
143 Porcine circovirus 2 Postweaning multisystemic wasting syndrome 8 7 1 2 4
144 Porcine parvovirus SMEDI, reproductive failure 19 19 0 0 0
145 Porcine respiratory and reproductive syndrome virus Porcine Reproductive and Respiratory Syndrome (PRRS), Blue-Ear Pig Disease 17 10 6 0 7
146 Porcine rotavirus Diarrhea 2 2 0 0 1
147 Pseudorabies virus Aujeszky's disease 16 6 16 3 17
148 Psittacid herpesvirus 1 Pacheco's Parrot Disease 1 1 0 0 2
149 Rabbit hemorrhagic disease virus Rabbit hemorrhagic disease 1 0 1 0 2
150 Rabies virus Rabies 27 20 6 0 16
151 Reticuloendotheliosis Virus Tumors, wasting syndrome 1 0 3 0 0
152 Rift Valley Fever virus Rift valley fever 1 0 2 0 3
153 Rotavirus Gastroenteritis 13 9 8 2 11
154 Rubella virus Rubella 6 6 0 0 4
155 SARS-CoV Severe Acute Respiratory Syndrome (SARS) 2 0 2 0 4
156 Simian Immunodeficiency Virus Simian AIDS 3 0 3 0 9
157 Sindbis virus Encephalitis 1 0 1 0 1
158 Tick-borne Encephalitis Virus (TBEV) Tick-borne Encephalitis 3 1 2 0 3
159 Transmissible gastroenteritis virus Porcine transmissible gastroenteritis 5 5 0 0 0
160 Turkey hemorrhagic enteritis virus Hemorrhagic enteritis 1 1 0 0 1
161 Vaccinia virus 6 0 9 0 6
162 Varicella-zoster virus chickenpox / shingles 7 6 2 0 8
163 Variola virus Smallpox 14 2 17 0 34
164 VEE Virus Venezuelan equine encephalitis 30 15 6 0 44
165 Viral haemorrhagic septicaemia virus 3 0 2 0 3
166 West Nile virus West Nile fever 20 18 3 1 7
167 Western equine encephalomyelitis virus Western equine encephalomyelitis (WEE) 43 38 5 0 5
168 Yellow fever virus Yellow fever 3 1 2 65 10
Parasites
169 Babesia bovis Babesiosis, Texas Cattle Fever 2 0 4 0 6
170 Babesia canis Piroplasmosis 1 1 0 0 2
171 Cryptosporidium parvum Cryptosporidiosis 2 0 2 2 3
172 Eimeria maxima Coccidiosis 4 1 2 2 4
173 Eimeria spp. Coccidiosis 11 8 1 0 4
174 Eimeria tenella Hemorrhagic cecal coccidiosis 7 0 5 0 7
175 Entamoeba histolytica Amoebiasis 4 0 4 0 5
176 Giardia duodenalis Giardiasis (Beaver fever) 3 2 1 0 4
177 Leishmania amazonensis Leishmaniasis 4 0 5 0 5
178 Leishmania donovani Visceral leishmaniasis 15 1 13 4 16
179 Leishmania infantum Infantile visceral leishmaniasis 6 0 6 1 6
180 Leishmania major Cutaneous leishmaniasis 8 0 11 0 11
181 Neospora caninum Neosporosis 10 2 8 0 11
182 Plasmodium spp. Malaria 36 0 43 0 118
183 Sarcocystis neurona Equine protozoal myeloencephalitis 2 1 1 0 3
184 Schistosoma japonicum Schistosomiasis 7 0 5 0 5
185 Schistosoma mansoni Schistosomiasis 4 0 4 0 4
186 Theileria annulata Theileriosis 3 0 2 0 5
187 Theileria parva East Coast Fever 2 0 1 0 3
188 Toxoplasma gondii Toxoplasmosis 14 0 19 5 17
189 Trichomonas foetus 2 2 0 0 1
190 Trypanosoma brucei African trypanosomiasis (African Sleeping Sickness) 2 0 2 0 3
191 Trypanosoma cruzi Chagas disease 14 0 16 0 17
Fungi
192 Coccidioides spp. Coccidioidomycosis (California disease, Desert rheumatism, San Joaquin valley fever, and Valley fev 4 0 9 0 9
Other diseases
193 Allergy Allergy 1 0 16 0 18
194 Arthritis 4 0 4 6 6
195 Atherosclerosis Atherosclerosis, arteriosclerotic vascular disease (ASVD) 2 0 0 0 3
196 Cancer Cancer 56 3 74 0 215
197 Diabetes Diabetes 4 0 5 0 9
198 Experimental autoimmune encephalomyelitis Experimental autoimmune encephalomyelitis (EAE) 1 0 3 0 11
199 Experimental autoimmune uveitis Experimental autoimmune uveitis 1 0 2 0 2
200 Ricin toxin of Ricinus communis Ricin poisoning 0 0 1 0 2
Total 200 3251 2165 1170 338 2194

Also, the VIOLIN database contains 24,345 abstracts and 10,317 full text PDF documents for 24,345 vaccine-related papers downloaded from PubMed.

Note: This table is automatically updated to reflect updated statistics in the VIOLIN database.