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VIOLIN Statistics

Currently, VIOLIN includes 3455 vaccines for 211 pathogens or non-infectious diseases (e.g., cancer). The vaccines annotated in VIOLIN include licensed vaccines, vaccines being tested in clinical trials, and vaccines that have been studied in research and experimentally verified effective in at least one laboratory animal model. See detailed curated data here:

Index Pathogen Name Disease No. of Vaccines No. of Licensed Vaccines No. of Vaccine-related
pathogen genes
No. of Vaccine-related
host genes
No. of References
Bacteria
G+ Bacteria
1 Bacillus anthracis Anthrax 28 4 17 0 47
2 Clostridium botulinum Botulism 18 8 7 0 21
3 Clostridium perfringens Food poisioning, Gas gangrene 6 6 0 0 0
4 Clostridium tetani Tetanus 62 57 2 0 18
5 Corynebacterium diphtheriae Diphtheria 22 22 1 0 16
6 Erysipelothrix rhusiopathiae Erysipelas 29 28 1 0 3
7 Listeria monocytogenes Listeriosis 4 0 4 1 8
8 Mycobacterium avium 2 0 1 4 3
9 Mycobacterium bovis Tuberculosis 2 1 1 0 2
10 Mycobacterium marinum 1 0 1 0 2
11 Mycobacterium tuberculosis Tuberculosis 47 2 43 39 84
12 Staphylococcus aureus Staph infections 8 0 7 2 11
13 Streptococcus agalactiae Group B streptococcus (GBS) infection 4 0 4 0 7
14 Streptococcus equi Strangles (also equine distemper) 5 2 7 1 9
15 Streptococcus pneumoniae Pneumonia 18 6 13 0 26
16 Streptococcus pyogenes Group A streptococcal infections, Strep throat, Scarlet fever 7 0 5 2 9
17 Streptococcus suis 1 0 0 0 1
G- Bacteria
18 Actinobacillus pleuropneumoniae porcine pleuropneumonia 15 2 16 2 19
19 Aeromonas hydrophila 2 0 1 0 3
20 Aeromonas salmonicida Furunculosis, Bald sea urchin disease 3 2 3 0 6
21 Bordetella avium Bordetellosis 2 2 0 0 2
22 Bordetella bronchiseptica Infectious bronchitis, kennel cough 10 6 5 5 7
23 Bordetella pertussis Whooping Cough 28 16 14 0 27
24 Borrelia burgdorferi Lyme Disease 14 6 5 0 6
25 Brucella spp. Brucellosis 60 7 46 9 119
26 Burkholderia pseudomallei Melioidosis 7 0 8 1 7
27 Campylobacter fetus bovine venereal campylobacteriosis (BVC) 17 17 0 0 0
28 Campylobacter jejuni Campylobacterosis 11 0 10 2 32
29 Chlamydia muridarum 10 0 10 3 7
30 Chlamydia trachomatis Chlamydia 4 0 1 0 6
31 Chlamydophila abortus Abortion and fetal death 10 1 10 1 5
32 Chlamydophila pneumoniae Pneumonia 6 0 6 2 6
33 Chlamydophila psittaci Respiratory psittacosis, avian chlamydiosis 18 17 3 0 4
34 Coxiella burnetii Q fever 6 0 2 1 30
35 Edwardsiella ictaluri Enteric septicemia of channel catfish (ESC) 2 1 1 1 3
36 Edwardsiella tarda 9 0 8 0 6
37 Escherichia coli Hemorrhagic colitis 42 14 25 4 44
38 Flavobacterium columnare Columnaris 1 1 0 0 1
39 Francisella tularensis Tularemia 25 1 24 15 31
40 Haemophilus influenzae Meningitis 30 11 15 3 59
41 Haemophilus parasuis Glasser's disease 4 3 1 0 2
42 Haemophilus somnus 24 24 0 0 1
43 Helicobacter pylori Ulcers 12 0 9 0 13
44 Lawsonia intracellularis Lawsonia intracellularis infection 4 4 0 0 3
45 Leptospira spp. Leptospirosis 132 130 2 0 3
46 Mannheimia haemolytica Bovine Respiratory Disease 16 15 1 0 2
47 Mycoplasma gallisepticum Chronic respiratory disease 14 12 2 1 5
48 Mycoplasma hyopneumoniae Porcine Enzootic Pneumonia 11 10 1 0 2
49 Mycoplasma synoviae Respiratory tract disease and synovitis 1 1 0 0 1
50 Neisseria meningitidis Meningitis 18 9 24 0 19
51 Pasteurella multocida Pasteurellosis, fowl cholera 21 17 4 2 5
52 Piscirickettsia salmonis Salmon Rickettsial Disease, Piscirickettsiosis 1 1 0 0 1
53 Porphyromonas gulae Canine periodontitis 1 1 0 0 1
54 Pseudomonas aeruginosa Pseudomonas aeruginosa infection 11 4 4 0 7
55 Rickettsia spp Spotted Fever, Typhus 2 0 3 1 6
56 Riemerella anatipestifer New duck disease, Infectious serositis, Pasteurella anatipestifer infection 1 1 0 0 1
57 Salmonella spp. Salmonellosis 62 19 61 13 57
58 Shigella Shigellosis 24 2 14 4 25
59 Treponema pallidum Syphilis 3 0 3 0 6
60 Vibrio anguillarum (Listonella anguillarum) Vibrosis 2 2 1 0 2
61 Vibrio cholerae Cholera 4 2 4 2 6
62 Yersinia enterocolitica Yersiniosis 5 0 5 2 6
63 Yersinia pestis Plague 29 2 36 1 57
64 Yersinia pseudotuberculosis Yersiniosis 1 0 2 0 4
65 Yersinia ruckeri Enteric redmouth disease 2 1 1 0 3
Viruses
66 Adenovirus Respiratory infection 1 1 0 0 2
67 African horse sickness virus 2 0 0 0 2
68 African Swine Fever Virus African Swine Fever 2 0 1 0 4
69 Avian Encephalomyelitis Virus Avian Encephalomyelitis 13 13 0 0 3
70 Avian Paramyxovirus 4 3 0 0 2
71 Avian pneumovirus Turkey rhinotracheitis, Avian rhinotracheitis, Swollen head syndrome 2 1 1 0 1
72 Avian Polyomavirus Papovavirus, Budgerigar fledgling disease, Psittacine polyomavirus 1 1 0 0 1
73 Avian Reovirus Viral Arthritis, Pale Bird Syndrome, Tenosynovitis 36 36 0 0 1
74 Bluetongue virus Bluetongue disesase 6 1 0 0 6
75 Borna disease virus 1 0 0 0 1
76 Bovine coronavirus 5 5 0 0 0
77 Bovine herpesvirus 1 Infectious bovine rhinotracheitis 159 146 9 0 22
78 Bovine Leukemia virus 1 0 1 0 3
79 Bovine papillomavirus Warts 1 1 0 0 0
80 Bovine Parainfluenza 3 Virus (BPIV-3) 108 108 0 0 1
81 Bovine Respiratory Syncytial Virus Respiratory Disease 55 53 2 0 4
82 Bovine viral diarrhea virus 1 Bovine viral Diarrhea (BVD) 129 128 0 0 2
83 Bovine viral diarrhea virus 2 Bovine viral diarrhea 1 0 1 0 3
84 Canarypox virus Canary Pox 1 1 0 0 0
85 Canine adenovirus type 1 Fox Encephalitis, Infectious Canine Hepatitis 3 3 0 0 1
86 Canine Adenovirus Type 2 57 57 0 0 1
87 Canine coronavirus Intestinal disease 41 41 0 0 2
88 Canine distemper virus Canine distemper 79 75 2 0 4
89 Canine parainfluenza virus 56 56 0 0 1
90 Canine parvovirus Canine parvovirus infection 68 66 2 1 3
91 Caprine herpesvirus type 1 (CpHV-1) 1 0 0 0 1
92 Chicken Anemia Virus Chicken infectious anemia, Blue wing disease, Anemia dermatitis syndrome, Hemorrhagic aplastic anemi 3 3 0 0 1
93 chikungunya virus 1 0 0 0 1
94 Classical swine fever virus Classical swine fever, hog cholera 14 3 7 0 15
95 Corynebacterium pseudotuberculosis 1 0 0 0 1
96 Crimean-Congo Haemorrhagic Fever (CCHF) 1 0 0 0 1
97 Dengue Virus Dengue Fever 17 0 11 0 18
98 Duck enteritis virus Duck Plague 1 1 0 0 1
99 Duck hepatitis virus 1 Duck virus hepatitis (DVH) 2 1 1 0 2
100 Eastern Equine Encephalitis Virus Encephalitis 38 38 0 0 1
101 Ebola virus Ebola hemorrhagic fever 29 0 17 0 29
102 Equid herpesvirus Equine Rhinopneumonitis 24 20 3 0 3
103 Equine arteritis virus Equine arteritis 1 1 0 0 0
104 Equine rotavirus Rotaviral Diarrhea 1 1 0 0 1
105 Feline calicivirus Feline Respiratory Infections 35 34 0 0 2
106 Feline herpesvirus 1 Feline viral rhinotracheitis 34 33 1 0 2
107 Feline immunodeficiency virus Feline AIDS 6 3 2 0 3
108 Feline infectious peritonitis virus Feline infectious peritonitis (FIP) 3 1 5 0 2
109 Feline leukemia virus Feline leukemia virus infection 18 16 3 0 4
110 Feline panleukopenia virus Feline Distemper 32 32 0 0 2
111 Foot-and-mouth disease virus Foot-and-mouth disease 4 0 8 0 5
112 Fowlpox virus Fowlpox 20 20 0 0 2
113 Gallid herpesvirus 1 Avian infectious laryngotracheitis, Fowl Laryngotracheitis 14 10 5 0 5
114 Hantavirus Hantavirus Pulmonary Syndrome 13 0 11 2 15
115 Hendra virus Hendra virus disease 1 0 1 0 2
116 Hepatitis A virus Hepatitis A 8 8 1 0 9
117 Hepatitis B virus Hepatitis B 20 7 10 0 33
118 Hepatitis C virus Hepatitis C 0 0 1 0 1
119 Hepatitis D virus 1 0 1 0 2
120 Hepatitis E virus Hepatitis E 0 0 1 0 2
121 Herpes simplex virus type 1 and 2 Herpes 29 0 18 1 33
122 Hirame rhabdovirus 3 1 2 0 3
123 Human coxsackievirus 1 0 1 0 2
124 Human cytomegalovirus 2 0 2 0 2
125 Human Immunodeficiency Virus Acquired Immunodeficiency Syndrome (AIDS) 39 0 52 13 103
126 Human metapneumovirus Respiratory tract infection 2 0 2 0 2
127 Human Papillomavirus HPV infection 13 2 5 0 24
128 Human Respiratory Syncytial Virus Respiratory tract disease 4 0 3 0 5
129 Infectious Bronchitis Virus (IBV) Infectious Bronchitis 88 83 3 0 8
130 Infectious Bursal Disease Virus (IBDV) Infectious Bursal Disease 93 85 2 0 8
131 Infectious Hematopoietic Necrosis Virus Infectious hematopoietic necrosis 7 1 3 0 8
132 infectious laryngotracheitis virus 5 0 0 0 4
133 Infectious pancreatic necrosis virus 1 0 2 0 2
134 Infectious salmon anemia virus Infectious Salmon Anemia 1 1 0 0 2
135 Influenza virus Influenza (flu) 187 89 53 102 131
136 Japanese encephalitis virus Japanese encephalitis 13 2 7 1 13
137 Lassa Fever Virus Lassa fever 13 0 3 0 8
138 Lymphocytic choriomeningitis virus Lymphocytic choriomeningitis 1 0 2 0 1
139 Marburg Virus Hemorrhagic fever 18 0 18 0 12
140 Marek's disease virus Marek's disease 53 51 2 0 3
141 Measles virus Measles 14 9 5 1 13
142 Mink enteritis virus Mink Enteritis 10 10 0 0 1
143 Mumps virus Mumps 7 5 1 0 5
144 Murine Cytomegalovirus 2 0 3 0 3
145 Murine leukemia virus 0 0 1 0 1
146 Newcastle disease virus Newcastle disease 100 95 3 0 8
147 Nipah virus Nipah virus disease 4 0 2 0 5
148 Orf Virus Orf disease, Sore mouth (Ovine Ecthyma) 2 2 0 0 1
149 Parainfluenza virus 0 0 2 0 1
150 Pigeonpox virus Pigeon Pox 3 3 0 0 1
151 Poliovirus Polio 13 13 1 0 8
152 Porcine circovirus 2 Postweaning multisystemic wasting syndrome 11 7 1 2 9
153 Porcine parvovirus SMEDI, reproductive failure 19 19 0 0 0
154 Porcine respiratory and reproductive syndrome virus Porcine Reproductive and Respiratory Syndrome (PRRS), Blue-Ear Pig Disease 17 10 6 0 7
155 Porcine rotavirus Diarrhea 2 2 0 0 1
156 Pseudorabies virus Aujeszky's disease 18 6 16 3 19
157 Psittacid herpesvirus 1 Pacheco's Parrot Disease 1 1 0 0 2
158 Rabbit hemorrhagic disease virus Rabbit hemorrhagic disease 3 0 1 0 4
159 Rabies virus Rabies 34 20 6 0 22
160 Reticuloendotheliosis Virus Tumors, wasting syndrome 1 0 3 0 0
161 Rift Valley Fever virus Rift valley fever 3 0 2 0 5
162 rinderpest virus 2 0 0 0 2
163 Rotavirus Gastroenteritis 14 9 8 2 13
164 Rubella virus Rubella 6 6 0 0 4
165 SARS-CoV Severe Acute Respiratory Syndrome (SARS) 5 0 3 0 9
166 Simian Immunodeficiency Virus Simian AIDS 7 0 8 0 13
167 Sindbis virus Encephalitis 1 0 1 0 1
168 Tick-borne Encephalitis Virus (TBEV) Tick-borne Encephalitis 3 1 2 0 3
169 Transmissible gastroenteritis virus Porcine transmissible gastroenteritis 5 5 0 0 0
170 Turkey hemorrhagic enteritis virus Hemorrhagic enteritis 1 1 0 0 1
171 Vaccinia virus 6 0 9 0 6
172 Varicella-zoster virus chickenpox / shingles 7 6 2 0 8
173 Variola virus Smallpox 14 2 17 0 34
174 VEE Virus Venezuelan equine encephalitis 30 15 6 0 44
175 Viral haemorrhagic septicaemia virus 3 0 2 0 3
176 West Nile virus West Nile fever 23 18 3 1 12
177 Western equine encephalomyelitis virus Western equine encephalomyelitis (WEE) 43 38 5 0 5
178 Yellow fever virus Yellow fever 3 1 2 1100 10
Parasites
179 Babesia bovis Babesiosis, Texas Cattle Fever 2 0 4 0 6
180 Babesia canis Piroplasmosis 1 1 0 0 2
181 Cryptosporidium parvum Cryptosporidiosis 2 0 2 2 3
182 Eimeria maxima Coccidiosis 4 1 2 2 4
183 Eimeria spp. Coccidiosis 11 8 1 0 4
184 Eimeria tenella Hemorrhagic cecal coccidiosis 7 0 5 0 7
185 Entamoeba histolytica Amoebiasis 4 0 4 0 5
186 Giardia duodenalis Giardiasis (Beaver fever) 3 2 1 0 4
187 Leishmania amazonensis Leishmaniasis 4 0 5 0 5
188 Leishmania donovani Visceral leishmaniasis 16 1 13 4 17
189 Leishmania infantum Infantile visceral leishmaniasis 7 0 6 1 7
190 Leishmania major Cutaneous leishmaniasis 10 0 11 0 13
191 Neospora caninum Neosporosis 11 2 8 0 12
192 Plasmodium spp. Malaria 44 0 45 0 125
193 Sarcocystis neurona Equine protozoal myeloencephalitis 2 1 1 0 3
194 Schistosoma japonicum Schistosomiasis 9 0 5 0 5
195 Schistosoma mansoni Schistosomiasis 4 0 4 0 4
196 Theileria annulata Theileriosis 3 0 2 0 5
197 Theileria parva East Coast Fever 2 0 1 0 3
198 Toxoplasma gondii Toxoplasmosis 16 0 19 5 18
199 Trichinella spiralis 1 0 0 0 1
200 Trichomonas foetus 2 2 0 0 1
201 Trypanosoma brucei African trypanosomiasis (African Sleeping Sickness) 2 0 2 0 3
202 Trypanosoma cruzi Chagas disease 14 0 16 0 17
Fungi
203 Coccidioides spp. Coccidioidomycosis (California disease, Desert rheumatism, San Joaquin valley fever, and Valley fev 4 0 9 0 9
Other diseases
204 Allergy Allergy 1 0 16 0 18
205 Arthritis 4 0 4 6 6
206 Atherosclerosis Atherosclerosis, arteriosclerotic vascular disease (ASVD) 2 0 0 0 3
207 Cancer Cancer 71 3 74 0 222
208 Diabetes Diabetes 4 0 5 0 9
209 Experimental autoimmune encephalomyelitis Experimental autoimmune encephalomyelitis (EAE) 1 0 3 0 11
210 Experimental autoimmune uveitis Experimental autoimmune uveitis 1 0 2 0 2
211 Ricin toxin of Ricinus communis Ricin poisoning 0 0 1 0 2
Total 211 3455 2168 1185 1373 2385

Also, the VIOLIN database contains 24,345 abstracts and 10,317 full text PDF documents for 24,345 vaccine-related papers downloaded from PubMed.

Note: This table is automatically updated to reflect updated statistics in the VIOLIN database.