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Avian Paramyxovirus

Table of Contents
  1. General Information
    1. NCBI Taxonomy ID
    2. Introduction
  2. Vaccine Information
    1. Avian Paramyxovirus Type 1, Killed Virus Vaccine (USDA: 10C5.11)
    2. Avian Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 10C5.10)
    3. Inactivated PMV-3 Vaccine with Specol
    4. Newcastle-Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 17P5.10)
  3. References
I. General Information
1. NCBI Taxonomy ID:
260963
2. Introduction
Avian paramyxoviruses 1 through 9 are species of virus in the genera Avulavirus. Newcastle disease virus is another species in the same genus. Avian paramyxoviruses (APMV) consist of nine known serotypes. The APMVs are separated into distinct serotypes using Hemagglutination_assay and Neuraminidase assay. All the APMVs hemagglutinate chicken RBCs except for APMV-5 which does not hemagglutinate any species RBC making it unique among the APMVs (Wiki: Avain paramyxovirus).
II. Vaccine Information
1. Avian Paramyxovirus Type 1, Killed Virus Vaccine (USDA: 10C5.11)
a. Manufacturer:
Lohmann Animal Health International
b. Vaccine Ontology ID:
VO_0001603
c. Type:
Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Chicken
2. Avian Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 10C5.10)
a. Manufacturer:
Lohmann Animal Health International
b. Vaccine Ontology ID:
VO_0001604
c. Type:
Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Chicken
3. Inactivated PMV-3 Vaccine with Specol
a. Vaccine Ontology ID:
VO_0004222
b. Type:
Inactivated or "killed" vaccine
c. Status:
Research
d. Antigen
formalin inactivated PMV-3 strain 1388/84 (Beck et al., 2003).
e. Adjuvant: Specol
f. Immunization Route
Intramuscular injection (i.m.)
g. Chicken Response
  • Vaccination Protocol: The cockerels of each test group were vaccinated twice at an interval of 4 weeks. The first vaccination was carried out by the i.m. route, the booster vaccination was given by the s.c. route. After the vaccination, all animals were observed daily for clinical signs for the period of 8 weeks. The site of vaccine injection has been controlled weekly to assess local side effects (Beck et al., 2003).
  • Immune Response: The adjuvant Specol was that of the highest efficacy in chicken and produced only medium-sized inflammations on the CAM (Beck et al., 2003).
4. Newcastle-Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 17P5.10)
a. Manufacturer:
Lohmann Animal Health International
b. Vaccine Ontology ID:
VO_0002184
c. Type:
Inactivated or "killed" vaccine
d. Status:
Licensed
e. Location Licensed:
USA
f. Host Species for Licensed Use:
Chicken
III. References
1. Beck et al., 2003: Beck I, Gerlach H, Burkhardt E, Kaleta EF. Investigation of several selected adjuvants regarding their efficacy and side effects for the production of a vaccine for parakeets to prevent a disease caused by a paramyxovirus type 3. Vaccine. 2003; 21(9-10); 1006-1022. [PubMed: 12547615].
2. Wiki: Avain paramyxovirus: Wiki: Avain paramyxovirus [http://en.wikipedia.org/wiki/Avian_paramyxovirus]