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Vaccine Comparison
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BV-RVG/RVG |
| Vaccine Information |
- Vaccine Ontology ID: VO_0004651
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- Glycoprotein G
gene engineering:
- Type: Recombinant protein preparation
- Description: The recombinant baculovirus (BV-RVG/RVG) was pseudotyped with the rabies virus glycoprotein (RVG) and also simultaneously expressed another RVG under the control of the immediate early CMV promoter (Wu et al., 2014).
- Detailed Gene Information: Click Here.
- Preparation: Recombinant baculovirus (BV-RVG/RVG) was pseudotyped with the rabies virus glycoprotein (RVG) and also simultaneously expressed another RVG under the control of the immediate early CMV promoter (Wu et al., 2014).
- Immunization Route: Intramuscular injection (i.m.)
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| References |
Wu et al., 2014: Wu Q, Yu F, Xu J, Li Y, Chen H, Xiao S, Fu ZF, Fang L. Rabies-virus-glycoprotein-pseudotyped recombinant baculovirus vaccine confers complete protection against lethal rabies virus challenge in a mouse model. Veterinary microbiology. 2014; 171(1-2); 93-9101. [PubMed: 24793501].
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Rabies virus glycoprotein G mutant vaccine |
| Vaccine Information |
- Vaccine Ontology ID: VO_0002991
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse, hamster
- Glycoprotein G
gene engineering:
- Type: Gene mutation
- Description: This glycoprotein G mutant is from Rabies virus (Wu et al., 2011).
- Detailed Gene Information: Click Here.
- Immunization Route: Intramuscular injection (i.m.)
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| References |
Wu et al., 2011: Wu X, Franka R, Henderson H, Rupprecht CE. Live attenuated rabies virus co-infected with street rabies virus protects animals against rabies. Vaccine. 2011; ; . [PubMed: 21514343].
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Rabies virus P protein mutant vaccine |
| Vaccine Information |
- Vaccine Ontology ID: VO_0002992
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- P protein
gene engineering:
- Type: Gene mutation
- Description: This P protein mutant is from rabies virus (Morimoto et al., 2005).
- Detailed Gene Information: Click Here.
- Immunization Route: Intracranial immunization
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| References |
Morimoto et al., 2005: Morimoto K, Shoji Y, Inoue S. Characterization of P gene-deficient rabies virus: propagation, pathogenicity and antigenicity. Virus research. 2005; 111(1); 61-67. [PubMed: 15896403].
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RCN-rabies-G |
| Vaccine Information |
- Vaccine Ontology ID: VO_0004693
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- Glycoprotein G
gene engineering:
- Type: Recombinant vector construction
- Description: A recombinant RCN vaccine expressing the rabies-G glycoprotein (RCN/rabies-G) (Osorio et al., 1999).
- Detailed Gene Information: Click Here.
- Preparation: Recombinant RCN vaccine expressing the rabies-G glycoprotein (RCN/rabies-G) (Osorio et al., 2003).
- Immunization Route: Intramuscular injection (i.m.)
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| References |
Osorio et al., 1999: Osorio JE, Tomlinson CC, Frank RS, Haanes EJ, Rushlow K, Haynes JR, Stinchcomb DT. Immunization of dogs and cats with a DNA vaccine against rabies virus. Vaccine. 1999; 17(9-10); 1109-1116. [PubMed: 10195621].
Osorio et al., 2003: Osorio JE, Frank RS, Moss K, Taraska T, Powell T, Stinchcomb DT. Raccoon poxvirus as a mucosal vaccine vector for domestic cats. Journal of drug targeting. 2003; 11(8-10); 463-470. [PubMed: 15203914].
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rLSDV-Rabies-gP |
| Vaccine Information |
- Vaccine Ontology ID: VO_0004762
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- Glycoprotein G
gene engineering:
- Type: Recombinant vector construction
- Description: Recombinant LSDV encoding the rabies glycoprotein (rLSDV-RG) (Aspden et al., 2003).
- Detailed Gene Information: Click Here.
- Preparation: Using the rabies virus glycoprotein (RG) as a model antigen, the recombinant LSDV encoding the rabies glycoprotein (rLSDV-RG) was able to express RG (Aspden et al., 2003).
- Immunization Route: Intramuscular injection (i.m.)
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| References |
Aspden et al., 2003: Aspden K, Passmore JA, Tiedt F, Williamson AL. Evaluation of lumpy skin disease virus, a capripoxvirus, as a replication-deficient vaccine vector. The Journal of general virology. 2003; 84(Pt 8); 1985-1996. [PubMed: 12867628].
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