- Vaccine Ontology ID: VO_0004627
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Human
- Host Species as Laboratory Animal Model: mouse
- Antigen: CPA/CPB(Zahedifard et al., 2014)
- Vector:
- Vector: (Zahedifard et al., 2014)
- Immunization Route: Intramuscular injection (i.m.)
- Description: A Leishmania major recombinant vector vaccine that uses a Salmonella vector and CPA/CPB as antigen (Zahedifard et al., 2014).
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- Vaccine Ontology ID: VO_0004671
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- Host Species as Laboratory Animal Model: mouse
- KMP-11
gene engineering:
- Type: Recombinant protein preparation
- Description: Antigens were differentially expressed on the surface or in the cytosol of Salmonella typhimurium SL3261 (Schroeder et al., 2011).
- Detailed Gene Information: Click Here.
- Vector:
- Preparation: Salmonella expressing the novel Leishmania antigens LinJ08.1190 and LinJ23.0410 (Schroeder et al., 2011)
- Immunization Route: Intramuscular injection (i.m.)
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Zahedifard et al., 2014: Zahedifard F, Gholami E, Taheri T, Taslimi Y, Doustdari F, Seyed N, Torkashvand F, Meneses C, Papadopoulou B, Kamhawi S, Valenzuela JG, Rafati S. Enhanced protective efficacy of nonpathogenic recombinant leishmania tarentolae expressing cysteine proteinases combined with a sand fly salivary antigen. PLoS neglected tropical diseases. 2014; 8(3); e2751. [PubMed: 24675711].
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Schroeder et al., 2011: Schroeder J, Brown N, Kaye P, Aebischer T. Single dose novel Salmonella vaccine enhances resistance against visceralizing L. major and L. donovani infection in susceptible BALB/c mice. PLoS neglected tropical diseases. 2011; 5(12); e1406. [PubMed: 22216363].
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