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MIC3

Gene Name MIC3
Sequence Strain (Species/Organism) Toxoplasma gondii strain RH(ERP)
NCBI Nucleotide GI 5931753
NCBI Protein GI 5931754
Protein Accession CAB56644.1
Other Database IDs CDD:304395
CDD:283826
InterPro: IPR000742
InterPro: IPR006210
UniProtKB/TrEMBL: Q9GRG4
Taxonomy ID 5811
Gene Strand (Orientation) ?
Protein Name MIC3 microneme protein
Protein pI 6.42
Protein Weight 36421.86
Protein Length 421
Protein Note Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl21504
DNA Sequence
>gi|5931753|emb|AJ132530.1| Toxoplasma gondii MIC3 gene
CCGCTGTCCCGCCTGGTCAACAAGTATCACACCCTCGTCCCCGCCATTGGCACGGAGCTCGATGAGCTGC
AGTGTCGCTTTTAGGGGAGTCGTGCAATCACGCCGCAACACAGGCGTGATTCGATCTTCAATTGCTAGGT
AACCACTCGTGCTTGGTAGCTCTGCAATGGCTCGAGCGACGGGGGTGATGCAACATGCTGCTAAAAACTC
GACAGACGTGTCACCGGAACCCACCTAAATAGGAGACCACGGGTCTCTGGTGTGTCGCGTCGCATTCTCG
CGTCGCATTCTCGCGTCGCAATGACCGGCCAGTTGCTCGACGTCGCCAGCCGGGACTGAAGAGCGTTCAT
CGAGTCAGCAGCATTGCGTCCCCTTGCTCGGTGAAAAAAGACTCTCTGGTCGAGTCTAGCTCGTGTCACT
TCTGTTTCTAACCTCCTTCGTTCACCGGTACACCTCCGATGTGACTTTTGGTACACTTGCCCTGTCGCAC
GACGCACGCTGTCACTCAACTTGCTGCTAGCGCAATCGATAGGTTCCCTCGAACCAGCCATCACACACAC
ACCTTTTCCGGGAAGACGTTTGCGGGCGGTGGGTCGCAGCTCGTCGAGAGTGCGTTTCTGTGCATTTCTG
TGGGCAGTGCAGCGCGTTTGCGCGCCTTACTCTGTGTGTAACTTCCTTGTCCAACACTGGTAAAAATGCG
AGGCGGGACGTCCGCGCTGTTGCACGCGCTCACCTTCAGTGGGGCCGTGTGGATGTGCACCCCAGCGGAG
GCTTTGCCGATTCAGAAGTCTGTGCAGCTGGGCAGCTTTGACAAAGTTGTGCCGAGCCGCGAAGTCGTCT
CTGAGAGTCTTGCTCCGTCTTTCGCGGTGACTGAGACTCACTCGTCTGTGCAATCCCCCAGCAAGCAGGA
GACGCAACTCTGTGCTATCTCGAGTGAAGGCAAGCCATGTCGAAACCGTCAGTTGCACACTGACAACGGG
TACTTCATCGGGGCCAGTTGCCCCAAGAGCGCTTGCTGCAGCAAGACCATGTGCGGCCCCGGCGGCTGCG
GAGAATTCTGCTCCAGCAACTGGATTTTTTGCAGCAGTTCGCTCATCTACCATCCTGACAAAAGCTATGG
AGGAGACTGCAGCTGTGAAAAGCAGGGCCATCGGTGCGACAAAAACGCAGAATGCGTCGAAAACTTGGAC
GCGGGTGGGGGTGTGCACTGCAAGTGCAAAGACGGCTTCGTCGGCACTGGGTTGACTTGCTCCGAGGATC
CTTGTTCAAAAAGAGGGAACGCGAAGTGCGGACCCAACGGGACGTGCATCGTCGTCGATTCAGTCAGCTA
CACATGCACCTGCGGCGACGGCGAAACTCTAGTGAACCTCCCGGAAGGGGGACAAGGATGCAAGAGGACT
GGATGTCATGCCTTCAGGGAGAACTGCAGCCCTGGTAGATGTATTGATGACGCCTCGCATGAGAATGGCT
ACACCTGCGAGTGCCCCACAGGGTACTCACGTGAGGTGACTTCCAAGGCGGAGGAGTCGTGTGTGGAAGG
AGTCGAAGTCACGCTGGCTGAGAAATGCGAGAAGGAATTCGGCATCAGCGCGTCATCCTGCAAATGCGAT
AACGGATACTCCGGATCTGCTTCCGCAACCTCCCACCATGGGAAAGGAGAATCGGGATCCGAGGGGAGCT
TGAGTGAAAAAATGAATATTGTCTTCAAGTGCCCCAGTGGCTACCATCCAAGATACCATGCCCACACCGT
GACGTGTGAGAAAATTAAGCAGTGAGCTGGAGTCTGTCCTTTACTTTAGCATTGGAGAATGCGCCCATTC
GCAGCTGTCCGTGCATGCAATCATCGCCGTCTGTATAAAACCGACACAAACTGACCTTTATGTAACTGTA
CAGCTTTGCCCTTGACGGGGCCGGCAACCACGACACGACTACGTATGTCGCAAGACGAAGGTACCCAGCG
AGTCTCTGAGAGCGGAGATCAGCGCAAAGACAAGATGCAGAGTTTGACTCGAGAAACAATAGTAACACGA
AGTAAAAAGTCTCCACACTAAGCCAAGGATTGAGAATATTTCGATTTGTGCCGCTGGCAATAGTGGCCTT
GGCTAGAAAGAAGTTCTGCAACGAAGCGATCGGCTCACACGCGGATACACAGATGGGTTTGTACCGAGAA
CGTTAGGTTTGTGAACCGAGTTCAGGTAAAACAAAGTAGATTGTGTGCCTTTACGCAGACAGCGAGGGAA
AACATAG
Protein Sequence
>CAB56644.1 MIC3 microneme protein [Toxoplasma gondii]
MRGGTSALLHALTFSGAVWMCTPAEALPIQKSVQLGSFDKVVPSREVVSESLAPSFAVTETHSSVQSPSK
QETQLCAISSEGKPCRNRQLHTDNGYFIGASCPKSACCSKTMCGPGGCGEFCSSNWIFCSSSLIYHPDKS
YGGDCSCEKQGHRCDKNAECVENLDAGGGVHCKCKDGFVGTGLTCSEDPCSKRGNAKCGPNGTCIVVDSV
SYTCTCGDGETLVNLPEGGQGCKRTGCHAFRENCSPGRCIDDASHENGYTCECPTGYSREVTSKAEESCV
EGVEVTLAEKCEKEFGISASSCKCDNGYSGSASATSHHGKGESGSEGSLSEKMNIVFKCPSGYHPRYHAH
TVTCEKIKQ

Molecule Role Protective antigen
Related Vaccines(s) T. gondii DNA vaccine pMIC3i encoding the complete MIC3-ORF (RH(ERP) strain)
References