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NspA from N. meningitidis MC58
Gene Name	NspA from N. meningitidis MC58
Sequence Strain (Species/Organism)	Neisseria meningitidis MC58
VO ID	VO_0010979
NCBI Gene ID	902774
NCBI Protein GI	15676561
Locus Tag	NMB0663
Genbank Accession	AE002098
Protein Accession	NP_273705
3D structure: PDB ID	1P4T
Taxonomy ID	122586
Gene Starting Position	690297
Gene Ending Position	690821
Gene Strand (Orientation)	-
Protein Name	outer membrane protein
Protein pI	10.02
Protein Weight	17106.9
Protein Length	174
Protein Note	identified by similarity to EGAD:137514; match to protein family HMM PF02462
DNA Sequence	>NC_003112.2:690297-690821 Neisseria meningitidis MC58 chromosome, complete genome ATCAGAATTTGACGCGCACACCGGCGGACAGTTCGCCGGAACGGACGTTTTTGACAGTGTTGACTTTGCC GATGTAGTTGTAGCGGTAGCCGGCATCCAAATCGACATTCGGGGTAACGGCATAGCTTACGCCCGTCAAT ACGCCGAGGCCGATGGAGGTTTGGCTGAAGCTGTCGCTGCCGCCCAAGTCGACGGAGGCGCGGTTGAGGC TCAAGCGCGCGCCGAGATACGGTTTGACGGGCGATTGGGTGTCGAAGTCGTAAATGGCGGACGCGCCGAT GCTGTAAAGTTTGAAATCGGTGGATGGGGCTTTATAGTTTTTGTAGCGCGTGTAATCGACGGCGAAGCGG AGGTCGTTGATGCGGTAGCCTGCGGAGATGCGCGGGCTGAAGCCTTTGGCAGAACCTAAAGAGCTTGAGG CTTTTGCGTGTGCGGCATCGGCTTGGACGTAAAAGCCGGATGCGCCTTCCGCCAGTGCGGCGGCCGGGAG AGCGAGGGCAATCAGTGTGGCAAGTGCTTTTTTCA
Protein Sequence	>NP_273705.1 outer membrane protein [Neisseria meningitidis MC58] MKKALATLIALALPAAALAEGASGFYVQADAAHAKASSSLGSAKGFSPRISAGYRINDLRFAVDYTRYKN YKAPSTDFKLYSIGASAIYDFDTQSPVKPYLGARLSLNRASVDLGGSDSFSQTSIGLGVLTGVSYAVTPN VDLDAGYRYNYIGKVNTVKNVRSGELSAGVRVKF
Molecule Role	Protective antigen
Molecule Role Annotation	Protective antigen (Martin et al., 1997) NspA-containing outer membrane vesicles conferred protection against otherwise lethal intraperitoneal challenge of mice with N. meningitidis serogroup B, and sera raised against them mediated opsonophagocytosis of meningococcal strains expressing this antigen (O'dwyer et al., 2004).
Related Vaccines(s)	N. meningitidis NspA Protein Vaccine
References

NspA from N. meningitidis MC58