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Tbp2

Gene Name Tbp2
Sequence Strain (Species/Organism) Haemophilus influenzae 86-028NP
VO ID VO_0010865
NCBI Gene ID 3430457
NCBI Protein GI 68249580
Locus Tag NTHI1169
Genbank Accession CP000057
Protein Accession YP_248692
Taxonomy ID 281310
Gene Starting Position 1117518
Gene Ending Position 1119410
Gene Strand (Orientation) -
Protein Name transferrin-binding protein 2
Protein pI 8.28
Protein Weight 66447.12
Protein Length 630
Protein Note Similar to: HI0995, TBP2_HAEIN
DNA Sequence 
>NC_007146.2:1117518-1119410 Haemophilus influenzae 86-028NP, complete genome
TCTACTTGTTGGTTTTTTCTACTTGTCTTTTAGCTCCAAAGACAACTGCAGCTCTTGCATTTGGTGAATT
GGGTGGTGAAGGTACGGTTGAGGAACTTTCAGAATTTGTAGCTGTAGGATTGTTTCCGTTATAGGTGAAA
TAACCGCCTAATTCTGTAGCGTGCGGACCATAAAATGCCCCGTTTACTGTTGTCGTGAAATTGACTTTAG
ATGTGGCTTGTGTATTTTTGGGATCAATCACTACATTTGCGGTTGCTTTACCTTCGAAGGCATTACTACC
ATTTTTAAAGGTTGCCTCAATGTTAAACACGGTATTTTGTGAGTCGGCTCGTTTTAATTTGCCTGTTAAT
GTTTTATTGTCAAAATTGACATCAAACTCGGCGGGAGCATTTTTATCTTGTTGTTTATTTCCTGTAGTGG
AGTAAGATGTCTTGTCATCACCAATATAACCAAACCAACTACCGAGATATTTCACGTTTCCCGTTACAGG
AATTTGAGAACTGGGAGTACGGAGACCTAACAAAAATTGGTGGTATTGTCCTGTTTGATTTGTGTTTTTC
TTCTCTTTATCCTCATAATACATACCAAATTTTACATAGCTTAGATTCTTGCAACATGCTTCTACTTTAT
AGGTTTTATTTCCAATATCGTGATGTTTACTCGTTACGAAGTCATCAGTATCCCCTTCAGGGAAAAGAGG
AACAGGGTAATTATCAATTAAAAGGTAATCAGCTTCACCAAAACTTGATATATCTTTTGTCGTAAAGTTT
TTTTCATCGGTTTTTACATCGGCTGTTGTACTGGCTGTTGTACTGGTTGTTGCATCGGCTGTTTTAGTAG
AGAAAGTAATTAGCTTGCCATCAATTAAGGTTTCTTTGGATAATTTTTCCTTTTCTGTTTCTGGCGTTTC
TTTGGCACTAAATACCCCAAAAACTCGTTTATCCCTAGCTAAGAATTTACCCCCTAGTTCTTCAGCATTA
GGTCCATAAAAACCACCTTCTAATGTTCCCTCGCTGGTAAAGGGATGTTCATCCGATGTGGATTTCGTAG
GAGTAACTTTACCCCTGAATCTATTACTATAAATATGGGCATCTATATCATAGAGTTTTTCCTTTTCATA
TTGTTGAATATCAGTTTTTCTTTTGGTGTAAGACAGTTGTCCTGTCAGTTTTTTAGTCCCAAAATCTGCA
CTAAATTCACTTATTAAGCCTATATCACCATTCTTTGAATTATTTTCTAAATCAATATCTCCTCGAGTAG
CACTACGTCGAAAATAAGCTTGACCTCTAGCATTACTGAACAAAGAATAATTTTGGCCATATTTAGTTGC
AGTGATGAAATCCCAAGTTCCTTTATACGTTGCTACACCGCTTACTGGCAAGTCTGTTGCAGTTTTATTA
CCATAATAAAACGCATAACCATAATGGCCACTATAGGCTTTTTTTTCTGTTGCTAATTTGGAAAAGTCTT
TCCAATTCTCAATATAGTACAAACCAGAATAAACGTATTTTTGTAAATTGGGGTCTTGTAATGCTCTATT
AGGTTCAAGCCCAATTGGATTTGTATGTATTTTATTTTCTGTTTTAACATTTTTAACATCATCTTCAATC
GTAGAAGGTGAGGAAAAATATGATATATAGCCATTTTCATTTAAGAAACTAGGTTCTTTATTACCACTCA
GATTCTGAGCCACTAACTTCATCCCTCCTCCTAAAGAAGGAATGGACAACTTTTCCAAATTAGATTTTGT
TCTTGAACTTGAAGTATCGTCTTGATAACGTGGTTTAGAAGAGGAGGGATTAGAGACGTCATCTACATCA
AAAGAACCACCTCCCCCGCTACAAGCGCTTAATAAAAAGGAAAGTCCACCAGTGATAAGAGGTACAGATT
TCA
Protein Sequence 
>YP_248692.1 transferrin-binding protein 2 [Haemophilus influenzae 86-028NP]
MKSVPLITGGLSFLLSACSGGGGSFDVDDVSNPSSSKPRYQDDTSSSRTKSNLEKLSIPSLGGGMKLVAQ
NLSGNKEPSFLNENGYISYFSSPSTIEDDVKNVKTENKIHTNPIGLEPNRALQDPNLQKYVYSGLYYIEN
WKDFSKLATEKKAYSGHYGYAFYYGNKTATDLPVSGVATYKGTWDFITATKYGQNYSLFSNARGQAYFRR
SATRGDIDLENNSKNGDIGLISEFSADFGTKKLTGQLSYTKRKTDIQQYEKEKLYDIDAHIYSNRFRGKV
TPTKSTSDEHPFTSEGTLEGGFYGPNAEELGGKFLARDKRVFGVFSAKETPETEKEKLSKETLIDGKLIT
FSTKTADATTSTTASTTADVKTDEKNFTTKDISSFGEADYLLIDNYPVPLFPEGDTDDFVTSKHHDIGNK
TYKVEACCKNLSYVKFGMYYEDKEKKNTNQTGQYHQFLLGLRTPSSQIPVTGNVKYLGSWFGYIGDDKTS
YSTTGNKQQDKNAPAEFDVNFDNKTLTGKLKRADSQNTVFNIEATFKNGSNAFEGKATANVVIDPKNTQA
TSKVNFTTTVNGAFYGPHATELGGYFTYNGNNPTATNSESSSTVPSPPNSPNARAAVVFGAKRQVEKTNK
Molecule Role Protective antigen
Molecule Role Annotation Recombinant Tbp1 and Tbp2 proteins were expressed from Escherichia coli and antisera were raised to the purified proteins. In a passive model of bacteraemia, infant rats were protected from challenge with Hib after transfer of anti-rTbp2 antiserum, but not after anti-rTbp1 antiserum (Loosmore et al., 1996).
References