VIOLIN: Vaccine Investigation and Online Information Network

CEACAM3
Gene Name	CEACAM3
Sequence Strain (Species/Organism)	Homo sapiens
NCBI Gene ID	1084
NCBI Protein GI	461496471
Genbank Accession	AC022516
Protein Accession	NP_001264092
Taxonomy ID	9606
Chromosome No	19
Gene Starting Position	41796589
Gene Ending Position	41811552
Gene Strand (Orientation)	+
Protein Name	transcript variant 3
Protein pI	5.89
Protein Weight	20869.17
Protein Length	212
Protein Note	Also known as CEA; CGM1; W264; W282; CD66D; MGC119875
DNA Sequence	>NC_000019.10:41796589-41811552 Homo sapiens chromosome 19, GRCh38.p12 Primary Assembly CAGAGCCTAAGTCACAGTAGCCCTGACTACAGCATTCCTGGAGCCCAGGCTCTTTTCCACAGAGGAGGAA AGAGCAGGCAGCAGAGACCATGGGGCCCCCCTCAGCCTCTCCCCACAGAGAATGCATCCCCTGGCAGGGG CTTCTGCTCACAGGTGAGTGGAGGATTCCTGGGAGTGGGCAAGAGGAGGGATCACAGAGAATGGCTGGGG TCTCCTGGGGAGGATGGGGCTCTGATAGGGGACAGAAGGCTTCTGCTGAAGCCTCAGGGGAGAGAACATC AGAGAGGGACACGGGTCACAACAAGACAATCACATTGAACTGGGATTGATAAGAGGGAGGAAAATCCATT GATCATGTTTTCCAAGTTAATCATTACTGGCCACTACAATTAGAAAATGATAAGAATAAGAATTACATCA GGGTGATACTTTAAATAAAAATATAACCAGGGCACTAAAACCTGTCTTTGACCACCAACCACAAGTTGCA AAATAACCACCACTCCTTAACTCATCCACCAGTATTTGCAATCAAATTTTAGGCACTGGCGTACAACAAA TATCAGACAAGTCTCTGTGTTCAAAGAGCTTACACTCTTGCAGAGATGAAGATAGACACCCAAAGAGATC TAGAATGTGAGTTCAGGTGTTGACAAGAGCCCTGGAGGGAACAGAGCAGAAAAAGGTCAGAAAGGGAAGA CCCAGGGTCTCTAGAGGAGGTGTCAGGGGAGGGATCTCCCAAGGATGCCCTGATGTGAGCAGGATCTGAG GGCAGTGGGGAGGGAGCCATGCAGACCCCTGGGGAAGGGGATTCCACACAGGAAAATGCCAAGGTTAGAG GTGCTGAAGAAAGAAAGGTCACGTTACTGACCTTGACCAAGTGGGACACACATACACTCTCCAAGGCTGA AGGGTGAAGAGACTCTCTCAGGACCCAGGGCCCCATCTTTCCATCCCAATACATGGGTCCCAATATTGAC TGATGCTTTCTCCCTCCTAGCCTCACTTCTAAACTTCTGGAACCCGCCCACCACTGCCAAGCTCACTATT GAATCCATGCCGCTCAGTGTCGCAGAGGGGAAGGAGGTGCTTCTACTTGTCCACAATCTGCCCCAGCATC TTTTTGGCTACAGCTGGTACAAAGGGGAAAGAGTGGATGGCAACAGTCTAATTGTAGGATATGTAATAGG AACTCAACAAGCTACCCCAGGGGCCGCATACAGCGGTCGAGAGACAATATACACCAATGCATCCCTGCTG ATCCAGAATGTCACCCAGAATGACATAGGATTCTACACCCTACAAGTCATAAAGTCAGATCTTGTGAATG AAGAAGCAACTGGACAGTTCCATGTATACCGTGAGTATTTCCACATGACCTCTGGGTGTTGGGGGTCAGT TCTACTTCCCACATATGGGATTGTCAGGCCTGGGCTGTGCCTGTGGCCCTCTCTGCATTACATTCTGTAT CAGGGTTTGGACATTTAGTGCAGGACACACACGGGGGAGACAAACTTCCACAGATCAGAATTCCTTTCCT GCATCCAGACCCTGCAGACACTCGCTGCAGAGGAAGGACAGTCTGATGGGGGGACTCAGCAGGGCAAGGT CAGTGTCAGAAAAGAACCCCATGGTCTCCCCATGGACCTGACCCTAAGAAAGACCCTGGAGAACTGGATC AGGGCCTGGCCTGAGGGGTCCCCCTAGGATTCTCAGAGAGAAGCTCAACTCTTCCCAGAACTGAGCCCCT GTGCAAATCCCTGTCCCAGATTCCTGACTCCAGGTGACCCTGGGGACCCTAGGGATCCTGTGCCAGGGCT GAGTGAGGCCTCCTGGGCAGGGCTGACTGGGAGCAAGAATTTACCAGCTGTCTGAGGGTCGTGGCTCCTG GAGTTGGTCACCAGCCAGGGTCCAGCCCCAAGAACCTCTCCTGGGCAAGGACAGGGCCTCATCCTTTACC TGAGACTCAGCATGGAGTGAACAGATGGACAAGATTACTAGGGCATGAGCCCACTGCCCAGGGGAACTTA GATGACTCCATGGGAAGTTCAGTATCCCCAGGGGGAGGAAAAAGAAGAGAGAAGATGCTCCCAGCAGCTC CTTTTCCACAAGGGATCAGACTCAGGGACCTCTCTTTTGGAGGCAAATAAGCATAGATGCTGTTCCTTTG GGCAGCTCCTCTATACACAGCTGAGGTCAAGTAATTGTAAATATTTTGAGATTAATTCACAAACAACGTC ACAGCCAAATAGCACTTATCCTACTTATTGAAAAAAAAAATTGAGGAACAGGGAGACAGTCACCGACTAG GGTCACACAAGTCAAAGGTGTCAGATTAGAGTCACACGAGGTCTCTCTGCAGCCACAGCTGCCTCTTCTC CACCAGGGGACGGCTGGCGTTATTATTAGACATCTGCAGGCCTGAGACCAGTCCTAAGTTCTCTTTCCTT TTTCTTGGGCATCCACATCTCAGAGGGGGAGATTTTGGTCTGGAGAGTAAGGGGCAAATGGAAAATTAAT CAATTTTTCCTGATATAGTTTGGATGTTTATCCTCTCCAAATCTCATGTTGAAATGTGATCCCCAACATT GGAGGTGAGGCCTGGTGGGAGGCGATTGGATCATGGGGGGCTGTTTCTCATGAGTGGCTCAGCACCATCC CCTTGGTGACAAGTCAGTTCTCACTTTGAGTGCACAGGAGATCTGGTTCTTTAAAAGTGTGTGGCGCCTC CACACTCTCTCTTGCTCCTGCTTTTGCCACATGACACCACCTGCTCCCCCTTCTCCTTCCACCATGATTG TAAGCTTGCTGGGTCTCACCAGAAGCCGAGCAGACGCTGGTGCCATGCCTGTATAGCCTGCAGATCCCTG CATCAATTAAATCTCTTTTCTTTATAAATTACCCAGCCTCAGACATTTCCTTATAGTAACAAAAAATAGC CTAACACATTAGCCTAACCTAGAACTAAATCCCTTGTGTCAACAGAGTCAGTGCCAGGAATGTCCGGGCC TCCCTCTCAGATGCGCACCACTGCCCTCACTCGACCTGAAATCCTGTGTTTCCTGATGTGTCAGTGACAC TCCCACAGGAGGATAAAACACTCCCCACTCACACCCTGCACCAGCGCAGGGCCCAGTGAGAGACACACAC TCAGTAGTTCTCTGACGAAGGAGGGAAGGAATGAATGATGAATAATTCTTAAACTCTTCAGAGACCGGAT CTTGGATGCAGAATCCTATAAGGTTCTGGCCACACCTGTTTCCTGTCCCTCCAGGGGCCGGGATCCTTGT TGCATTCCTCTAACCCCTGCCCCTAAAGCTACCCCAAGAACCGCATCTCATGGGACTCTGGCACAGCTCA CCTGTGGGAAGGTTTTCAGGTCTCCCTGGTCCTGGTTTGTGGGCGGCAGGTCACCCAGGCGCCGAGGCAA GAGACCAAGGACACGAGCTGTTCCAGTATAATAAAATATAAAACAAGAAAAGTTATACCAGATATAGATC TTAGATATGATTATATGTGAATATCATTAATCATTAGTTGGTAGCAATTACTCTTTATTCCAGTATTATA ATAATCCTCGCTCTATAATCACAACCTAGGAAAAGCCAGGCCATACAGAGATAGGAGCTGGGGAGACATA GTGAGAAGTGACCAGAAGACAAGAGTGCGAGCCTTCTGTTATGCCCAGACAGGGCCACCAGAAGGGCTCC TTGGTCTAGCGGTGACACTAGCGCCTGGGAAGACGCCCGTTGCCAGGCAGACCGAGGTCTAGCGGTAGCG TAAGTGTCAAGGGAAAACACCCGCTACTTGGCAGACCGGGAAAGGGAGTCTCCCTTTCCCCGGGAGAGTT TAGAGAAGACTTTGCTCCTCCACCTCTTGTGGAGGGCCAGACACCAGTCAGGTCCACTCGCAGTTATCCG GAGGCCTAACCGTCTCCCTATGATGCTGTGCTTCAGTGGTCACGCTCCTAGTCCGCCTTCACGTTCCATC CTGTACGCCTGGCTCTGCCTTCTAGATAGCAGTAGTAAATTAGTGAAAGTACTAAAAGTCTCTGATATGC AGAAATAATGGCATAAGCTGTCTTTCTCTTTGTCTCCTCTCTCTCTCTGCCTCATCTGCCAGGCAGGGAA GGGCCCCCTGTCCAGTGGACACATGACCCACGTGACCTTACCTATCATTGGAGATGACTCACACTCTTTA CCCTCCCCCTTTTGCTTTGTATCCAATAAATAACAGCGCAGTCAGACATTCGGGGCCACTACCAGTCTCC GCGCATTGGTGGTAGTGATCCCCCCGGGGCCCAGCTGTCTGTTCTTTTATCTCTTTATCTTGTGTCTTCA TTTCTACACTCTCTCGTCTCCGCACATGGGGAGAGACCCACCGACCCTGTGGGGCTGGTCCCTACACTGG TTCTAGAATAACCAGGGGTCTCCTGGTCCCTAGGGTCTCTGAGGTCACTGTAGTCCCCACAGCTCACTGT GATGTAATCTCTGGCTATCTCTGCTACCCCTTGTCCCTTATCTTCCTCCCCTTTCACACCAGTGAGGATG CCCCTGCCCTGCACAGCTTCCTCCACCCTTAGGTCTTCCCCAGGAACTCCCTCTAACAAGACTGGCTGTT CTGTTCCCTTCCCACTCACACTGTGGCCTGGCCCACCTCCGGGGCAATAAAAAAAGGCACAGAAATCAGC TGGATCAGAGCCCCTGCCAGGCTTCATCATGAGCCAGTGTCCCCAGGCCACCAGGAGAACGAGCTTCCAC TGTGTCCCCACCCAGGGCTCTTTCCCTTCTTGAGGCCAACATGTGGAAAAGGCCACAGGACAGGGACGAG CGACTCCTCCACCTACTCTTGTAATTTCCCAGCAGGTTTTTCCTGCCACTGCACAGACAAAACCAATTCA CTGAGACCACGATATTGCAGTCAAGAAAGAGTTTAATTAATGCTAAGTAAGCCAAACAGTAAGACAAGAG TTTATTATTACTTAAATCAGCCTCCCTGGAGGCTTGAGATTAGAGTTTTTCATGGATAGTTTGATGGCAG GGGACTAGGGAATGGGGAAAGCTGATTGGTTGGGGATAAAATCATAGGGATGTGGCAACTGATCCTGGTG TGCTGAAACTGCCTCTGAGTGGGGGCCACAAGACCACTGAATCATGGGTCACAGTCCAGGTGGAGTCAGT CAGTTGCCAGAATGCAGAAGTCTGAGAAACATCTCAAAAGACCAATCTCAGGTTCTACAATAGTGATATT ATCTATGGGAGCAATTAGGGAAGTCACAAATCTTGTGACCCTCCCATAATGCTGATCTCGTAATGTTTCA TTAGTTTACAAAGGCAATCCCTGACAAAGAGGAAGTTAGTTTTAGGGAGGGACTATAATCATCCTTGCTT CAAAGTTAAACTATACACTGAATTTTTCCCATGGTTAGCCTGGCTTGTGCCCAGGAATGAGCAAGGACAG CCACCTTGAGGCTAGAAGCCAGATGAAGTCAGCCATGCTAGCTTACTCTCGCCATCTTAATCCTTGCAAA AGTGGTTTCACTCTCTACAATGACTCACCAGGGGTCAGAGGCAAGAGGAGAGGTCTGCAGTCCCCAAAGC TCATGGCTCATTTCACCCATTTCCCTCCCGACTCCACCCTCATTCAGCTATGGGGCTCCCATCCTCCAGT CATTCCCTAGAGACTTCTGGTGTCCAATTTGGCATGTAAGAAGCTTGAAATCTGTCACTCAGTTATAACA AGTATAAAACTGAACAAACTGAAAAATCAACAACTCTTTTAGATCCCTCAGAGAAGCTAGGCCTCGGTGT TAATTGCCCCGCATATTGGAGAGACCGACAGGCAAAGATGGAGCAGCACACCTCACCTGGGCAGAAGCCC AGGGACAGAAACCCTGCAGAACCAGCGCTGGGGTCAGAAATCTGAACTGTAACTGACAAATTGCTGGAGG CTCAGCATGGACATGCCCCAGAGTTAAACTAAACACTCCAGGGGAGGGATCAATCTTGGGGCTGGGACAA GGAGGGACTCTTTTGTGAGTCTTAACTCCTAGAGCTACCAGATTCTCATAGTGAATAGGCAACAAAGATC CCCTCCTCCTTCCTGAAGCGGGAGGGGGAAAGGAATTATTTGGAAAGATCTCCGTGAATTCTATTCTTCT TAGCAACAGCTGCCTTTAAGAGAAACTTTTACCAGAGCCTGACCTGCTGGGGTTTTATGGGAGCCTAACT GGCCTGGCAGTGGGTAAATGTCCAACTCCAGCCCCCTGTAGCCATCATGTCCCACCTAAGGGGGCAAAAA TACAGAGAGTCACTTATGAAGTTCACAGCCCAGGCTGCAGACCTCATCCAGGACCACAGAACCCTTCCCT CCCAACACTCACCACAGCGTCACTGAACACCTGCTCACCCAAGTTCCTTTTACCCAGAATATCATGTCTG GCTTTCAACAAAACTGCACAAGACAGACTAAGGCAAAAACAAAAAAAAATGCAATTTGAAACTCAGAACA ACAATCAGAACCAGACTCAGATGTGGCAGGGATGTTGAAATTAGCAGAACGGGAATTTAAAACAACTCTG GTTAATACAGTAAAGGTTATGATGGAAAAAGTAGACCCCATGCAGGAACAGATGGGTGATGTAAGCAGAG AGATCGATATTCTAAGACAGAACCAAAAGAAATGCTAGAGATAAAAAAAGAAACCCTCCTGTAAGGTAAA TGAAGAATGCCCTCAATGGGCTTACTGGTAGCCTGGACACAGCTGAGGAAAGAATCTCTAGCTTGAGGGT GTGTCAGTAGAAACTTCCAAAACTGAACAGCAAAGTTTTGTGTGTGTATGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTGTTGTTTTGTTTGTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTACCCCAGGCTGGAG TGAAGTGATGCTATCTCAGCTCACTGCAAGCTCTGCCTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCT CCCAAATAGCTGGGACCACAGGCGCCCGCCACCATGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGG AGTTTCACCGTGTTATCCAGGATGGTCTCGACCTCCCAACCTCATGATCTGCCCGCCTTGGCCTCCAAAA GTGCTGGGATTACAGGCATGAGCCACCATGCCCGGCCTGAAACAGCAAAGCTTTAAAAGAGTGGGAAAAG GCCGGGCGTGGTTGTTCATGCTTGTAATCCCTGCACTTTGGGAGGCTGAGGCGGGTGGATCACCTGAGGT CAGGAGTTCGAGACCAGCCTGGCCAACATGATGATACCCTGTCTCTACTAAAAATACAAAAAATTAGCCA GGCATGATGACAGATGCCTATAATCCCAGCTACTCAGGAGGCTGAGGCAAGAGAATTGCTTGAACCTGGG AGGTAGAGATTGTAGTGAGCCAAGATAGCGCGATTTCACTCCAGCCTGGGCAACAAGAGCAAAACTCTGC CTCAAAAAAAAAAAAAGAGTGGGTAAAAAAAGTGGAAAAGCAGATTCAACTTCACATTCAAGATTTTGTA TTGACAATGGCATATTTTATATTTTCTAAAAGCTGTAACATACATGTAATGGGAATACTGGTGGTTCCTG GGACCAGGTGGAGCTGGCCAGCCCTGTGCTGTCTGATGGGCCCACTGCTTGTTCCACACACATGTGTCCC TCATGATGATGCCATTATCATAAGATGGGGTCTTCGGGTGGGGAGATGCACCAGCCACCGGCATCTCACT TAGACTCTGCCCAATTCGGGCTAATTTAATCAAATTCTAGTTGTGTTTCCTGAGGCGTAAAGAAAAGGAG GAAGGTGTTTCATATGCCTGTTTAGGCCCCTTCCTATTTTGCCTAACTCTGCACAGGAAATTGAGGTGAG GGCTCTTTTGACATTTACTGACATACACACATCACATCTCCTAATTTGGTATTTTTCTTTTCTGTGTATT ATTGAGACATCTCAGACTTTCCCTCTGACCAGTTCTGTCTTCCTAACAGGACTCACAATTCTCTCTCTAC CCAGAGAGTCACTGATTTCAAACCAAAGTCAGCATCTTTCTTTGAGCTTAACATGATTATGCTGGTCTTC AGCATTTAGCAGACCTAAACCTTATTATGTTATCAAGAGAAATGCTACAGCAACCAATTGACCTCAGACC TTTCGACCATTAATAATAATTTCCACTGATAGAAAAAAAATTAATTTCCCCCAAATTTCTTTTTTTTTTT TCACTATAGTGAGATCATAACTCCTTTGTCTAAACTCCTGACAAATTTTTAAGGGCAAAATGGACTATTA CAGATGGAGAATCCCAAATCCAAAAATCCAAAATACAAAATGTGCCAATATCCAAAATTTTTTGACCACT GGCATGATGTTCAAAGGAAATGCTCACTGGAGCATTTTGAAATTTTAGATTTTCAGATTTGGGATGCTAA ACCGATACTTGTAATACAAATATTCCAAAATAAAAAATAATTAGAAATCCAAAACACTTTTGCTCTTATG CATAAGAGATACTCAAACTCTATTAATTATAGACACCAAGCTGTACAGCAGATCTCTAGAACCTCCATAT TTTGCATAATTGAAACTGCACACCCAAGGAACAACTCCCTGCCAGCCCTTGGAAATCACCACTCTGCTCT TTTATTCTTTTTTCTTCTTTTTTTTTTTTTTTTTTTTTTTTAGATAGAGTTTTACTCTTGTCACCCAGGC TGGAGTGCAATGGTGTGATCTTGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCCTAGCC TTCTTAAGTAGCTGGGATTACAGGCATGTGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGACG GGGTTTCACCATGTTGGCCAGGCTGGTCTGGAACTCCCGACCTCAGGTGATCCGCCCGCCTCAGCATCCC AAAAGGCTGGGATTACAGGCATGAGCCACCGCACCCGGTCTGCATTCTACTCTCTGATTCCATGAGTTTG ACTACTCTAGGGACCTCGTATTCGTGGAACCGTACAGTAGTTGTCCTTGTACGACTGACTTCTTTCACTT AACATAATCTCCAATGGGAGAAAATATTTGCAAAGATTCTTCCCAAATGTCTCTCTCATATCCATCAAAC ACAGAGTCCATGAGGACCAGATTGCCAGCAGCTTCATGCTCCCTCTTTCCACCAGTCAGTTCTGCATTTG CAAACGTTCATATGTATTTCTTATTAAGTTCCACGGAGTCCTCACCTGCCCTCTGCAGGAGGAGAAAACA CATTAAGGACTGAGGACAGAGAACATGGTTCTGCTCCAAAGCCACCAGCTCCTGCATGTCCCCGCCCTCT TTCTAAGTTGGGATTCTACTCTTCCTGTTGTTGTTGTTTGTTGTTGTTGTTGTTGTTGTTGTTTGTTGTT TGTTGTTGTTACGGAGTCTTGCTCTGTCACTCAGGCTGGAGTGCAGTCGTGTAATCTCGGCTCACTACAA CCTCTGCCTCCCAGGTTCAAGTGATTCTCCTTCCTCAGCCTCCCGAGTAGCTGGAATTACAGGCATGCTC CACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACTGGGTTTTTCGCCATGTTGGTCAGGCTGGTCT CGAACTCCTGACCTCAGGTGATCTGCCCACCTCGGCCTCCCCAAGTGCTGGGATTACAGGTGTGAGCCAC CGCACCCGGCCTTCTACTATACCTTTTACTGACTCACTGTCTCATGTCAGTCACCATGATATACCTGGAA AGAATAACCTCACCTTGTAATTCTGAGACCTCAGCACCAGCATGTTCCAGGTGAGGACCCCAAGGTCAGC CAGGCAGTCAGCCATCAGGGAAGGAACAGGAGAGGTGCCAGGGGATGTGACTCCTGGTCCTGTGTCTGTC CAACACCCAATGCTGCTGCTTAATTCACAGTTGAGAAAGTCTCTTCTTCTTTCACAGGCAGGCAGCCTCA CAGTCTCTGAGCCCTCAGACGGTCATGCATCTGTCTGTGACACACACATCTGTCTTCGTCTTTTTTTGTT TGTGTGTTTGTTTGTTTGTTTGCTTGTTTGTTTTGAGAGACAGAGTCTCACTCTGTCGCCCAGGCTGGAG TGCAGTGGTGCGATCTCGGCTCACTGCAAGCTCTGCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCT CCCAAGTAGCTGGGACTACAGGCGCCTGCCACCATGCCTGGCTAATTTTTTGTATTTTTTAGTAGAGACG GGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCGTGACCTCGTGATACGCCCGCCTCGGCCTCCCAA AGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCCTTGTCTTGGTCTTTTAAGGAGTGGAGTTGGCC AAAGAATAGGAGATGTTGATTCTGATTAAAATATGCCTGTGGAGGAATCACAGGTGCCACACAGGGCAAT CTTCTCTCTGTTTTCTGCACAGCGGAGCTGCCCAAGCCCTCCATCTCCAGCAACAACTCCAACCCCAAGG AGGACAAGGATGCTGTGGCCTTCACCTGTGAACCTGAGATTCACAGCACAACCTGCCTGTAGTGGGTAAA TGGTCAGAGCCTCCCGGTCAGTTCCAGGCTGCAGCTGTCCAATGACAAGAGGACCCTCACTCTACTCAGT GTCACAAGGAATGACACAGGACCCTATGAGTGTGAAATACCGAACCCAGTGGGTGCCAGCTACAGTGACC CAGTCACGCTGAATGTCCTCTGTATCTTCTGTTCCTCTGTGGCCCAGGCTTCCAGCCCAAATCCACACAG CCAGAGGCCAGGCCTCTCAGTCCCTCTCAAGTCCAGGGACTCAGACTCTCACCCAGGCTGGCCATCACTT CCTGTCCCAAGCAAACCTGGGCAGACCCAGCCTTGACCAAGAATAGGAGGGGAGAGGCTGCTCCTGTCCT GGGAGGCTCAGGGTCCACAGCCTGTGATGGGAGAAACAGGTGAATATCTCAGACCCAGACTCAGTGGACA GATTGGGTTTCGTTAGGACTTCAAGGTTGTGACTTGGCTCACAGGGACACTGTGGCTCTTCCACAGACCA GGAGCTTCCCCTTCCCTTTGATGATATCATCTATGACTTTATTCTCGCTACTCCAGATGGACCGGGCATT CCCACCATTTCCCCCCCAGACTCCTATTACCATCCAGGGGCAAATCTCAACCTCTCCTGCCACATGGCCT CTAACCCACCTGCACAGTACTCCTGGTTTGTCAGTGGAATGCTCCAGCAACACACACAAAAGCTCTTTAT CCCCAACATCGCAGTGGATAAGAGTGGATCCTATGCTTGCCTCGCCCATAACTCAGCCACTGGCCTCAGT ACAATCACAGTCAAGACAATCACAGTCTCTGCTAAGTGGATCCCTGGAGCATAGGCCCTGAGCCCTGGGT AAAGCCACTCAGTTTTCTGAAAGAGCCTAGAAGTTTATTTCCCAGCCCATGTCTTGGACACAAGCAAATC CCAAACTCTACCCTGAGCCCTCTCACTCCACCTCTGCAGGACCCCTCCTCCCCTTGTTGTTCTGATTTCT CACAGCTGACCTTGGGGCCAGCCTGGAATGTTGTACAAATTTTGTTTTATCACTTACGAGTTCTGTGACC TTCCTTGACTTACTGAGGTGCTTTAAGTCTCAGATTCTAACTCTGCAGCTGGGGGTGATGCCCCCTCTCC CTCAAGGTGATGTAAGGATGAGATGAGTTGTAGGTAGGTTGGTGCCCACTGGAACTGGCACATGGAAGGC CCCTGAAAACAGTCAATGAACATCATCCCTGCTTATCAGCATTGAGTTGATGCCAAGGGCCTGCCCTTTG TGAGTGTCATGGGATGGAAAAGGAGAAACAGAGGGAAGAGGCATGATGCGAGAGGAAGGAGGGACTAAAA GGCACAGGAGCAGGGTGAGGTGCAGGCACCTCTGGGACAATGTATGAGTTGGTGCCGCCCAGTGTGTCAA GCCTGCAGAAAATGGTGCCACCATGGAAAGCAAGGGAATCTGTGATGAGGACAACACAAGAGACTACACT CAGGCCCCATGGCATCTCCTTCTTCCCTGACTGCACACCTTCCCTGCAAGGCCCCTGTGGTTTCCTCTGG GATAGACTTGGGCCTCTATCCCCTTTGCCTTCTTCTTTCTGCAGAAGAAAATGCCCCAGGCCTTCCTGTG GGGGCCGTCGCCGGCATCGTGACCGGGGTCCTGGTCGGAGTGGCGCTGGTGGCCGCGCTGGTGTGTTTCC TGCTCCTTGCCAAAACTGGAAGGTACCACAGCTTTTTCCCATCCTTCTCCCACCCCCTAGGCTGACTCCA GGCCAAAAGAAAGGAGACCTTGTCCTGTATTCAGGGCCAGGCTCTCCACGGCCTCCCAAGTCCCCAGGGA TCCTTCCCTCTTATTCCACGGCTCCTCCCTCGTCAGCTCCTGACCCTGGGTTGCTGCCTCAACAGCTTCC TCCTCTGTGAATTTGGCCCAATTAAGGCCCCACCCCTGAGTGTGGCCCTAGTTCCCTCACACAGCAAAGC CACAGCTGCCTGGAGGGAGGGAGAGAAGGAGGGAGGGAAGTAGGGAGGGAGGGAGGGAGGGCGTGCTCTG TACTTGGTACCTCCCATTGTTCATTGAATCCATCCACACAGTGAGGGGGATTTGCAGGCTCCGGATCCTG GGCACCGTCACACAATGGGGAGTGGACCAGCCTGGACAGGCTGGGTGGGGTCAGTGCCCCCCATGGCTGA TGTGGTAACCATAGGCCCTGAGGTGTGAGATGGGAGAACCTGGGCCTCAGAACAGCATGTCCTGGAGCGT CCTTTGTGTCTCTTGCCAAGGGGTTGAGAGAGAGGACAAGGACACTGTCCCATTTCAGCATCACCAGCCC TGAGTGCAGGGTCTGGCCACAGCAGGGACACTGAGTTCCAGGAGAATCCAAGACACTTGCGGTCCCCTCC GTGTCCTGCACACGTGGCCCTGCTTTGCCTCTGGGGACTTGACCCTTCCTCTCAGGCAAACCCTCGTGGT CTGTTTCCTTCCTTGGGTCCTCAGTCCCTTTCCTGGGTCCCTGGGTCAATGTTCTCCTGGCCCGGCATCT GCCTGAGGGTCCTTCCCCTCTGCTCAGGACAGATGTGGGTTCCTAAAGCCTTTCCTCAACTCCCCTCTGC TGGGCTCCCCCTAACACAAACCTGAGGGAGACAGGAGGTCTCCATGCCCATCCTTGAAAATGGGTTTCCC TTCTTGTCCCCTGTTCGAACTCCAAAGTTGTGGCTTTTAACCTGGCACCCTCCCAAATGACCCTGACCTT TCCTAGAACCAGCATCCAGCGTGACCTCAAGGAGCAGCAGCCCCAAGCCCTTGCCCCTGGTGAGTGTCCT CTCAGCCCAGGTGTGGCTGGGAACCCCTAGGACAGCCCCACAGTGTCCGCTCCTGCCAGTCACTGCCAGG CAGACTCTGATCCTTTCCCGGGGGCTGCAAGGAGGATCTCATAAAACATCACACAGGGGACCCCAATTGC TTGGGTCAGCCCTCACCTGTGGGCTCTGGGTCATGGGTCACCTCCCCAACCTCAGCTGCTCAGGTATCTT AGAGCTGAGGACCCCCTACGCCTTCCTGGAGAGGGGATAAGGCTCTCCTCCCACCCTGCTGCTCACTCCT GTCTCTGTTTCCAGGCCGTGGTCCCTCCCACAGCTCTGCCTTCTCGGTAAGCCTGTCCCCTTCCAGCCCC TTTCTACTGGGGTCCCAGCTGTGCAGGCTCTGGGCAGAGGGACCATCAGCCCCCCAGCACAGAACAGACC CACCTTCCCCCAAAACACACAGGACAAGGCTAGCCCTGCCCTGGCCAGGAGCTGGGCCTCCCTACAGGGT CAGGACCACCCACGCCCTGTGCTGACCCCTCCCCGGGACCCTCCATCACCTGAGGAGACCCCTGGAGTGC AGCAGGTGCAGAGTGGACACTGGGACCATCAGTCAGGGGCCCACATTAACAAGGGTGCAGGGTGGGCCCA GCCAGGAAAAGGGTCAGGGTGCTGTGTCCACACTGGGAGGCTGAGCTCAGGGGCAGAGCTGGTCACTCCT GAGGGGAAATGACCAGAAGTAAACACAGAGAAGTAAATCCTGGCCAATCAGAGACAGGAAACTTCCAGGC TGGGCCTCCATGACCCTCCCTCCCTGTCCACAGATGTCCCCTCTCTCCACTGCCCAGGCCCCCCTACCCA ACCCCAGGACAGCAGCTTCCATCTATGAGGTGAGTGTGGGCCACGGATGTTCTGGTCCCACAGGCCCCAG GGGACCCAGGATCTTCCCCTACTGGCATCGGCTGAGCTCTGAGATTCAGGAAACTGCTGTGAAAATAAGA ACGGGGGTGGCGAGCAGAGGAGGGAGGGGCTTGGGAGCAGGAACCCCCTGAGCACAGCCAGGTTCAGCCC CAGAGCAGCCCTGGATGGGCCCAGAGCCTGGGAGACGCCACACCCTGTTCTGAGGAGACTAGAGGGGTCC AGGCCTCTTCTCTGTTTTAACAGGAATTGCTAAAACATGACACAAACATTTACTGCCGGATGGACCACAA AGCAGAAGTGGCTTCTTAGCTTCCTCCAGGAGCTGCTCCTGTGTGTTGATGGAGAGTCCCCAAGGCCCCC AGCCCTGGGGATGGGGAAGGACATGAAGCCTGAGCCAGAGAACCAGCTATAAGTCCTGAGAAGACACTGG TGTCTGGGGGCAGGGAGGGATGGGGGTCCCTGATGAATATCTGGAGACCTCGACAGCCTGCCCTAGGCCC TGGGTGGGTCAGGACAAAGGCCTCTCATCACCGCAGAAAGCGGGGGCTTGCAGGGAAAGTGAATGGGCCT GTGGCCCACCTGGGGTCACTTGGAAAGGATCTGAATAAAGGGGACCCTTCCTCT
Protein Sequence	>NP_001264092.1 carcinoembryonic antigen-related cell adhesion molecule 3 isoform 2 precursor [Homo sapiens] MGPPSASPHRECIPWQGLLLTASLLNFWNPPTTAKLTIESMPLSVAEGKEVLLLVHNLPQHLFGYSWYKG ERVDGNSLIVGYVIGTQQATPGAAYSGRETIYTNASLLIQNVTQNDIGFYTLQVIKSDLVNEEATGQFHV YQENAPGLPVGAVAGIVTGVLVGVALVAALVCFLLLAKTGRPWSLPQLCLLDVPSLHCPGPPTQPQDSSF HL
Molecule Role	Protective antigen
Molecule Role Annotation	The immunogenicity of the nominal antigen, carcinoembryonic antigen (CEA) has been studied, as well as that of an anti-idiotype antibody, 3H1, which mimics CEA and can be used as a surrogate for CEA. It has been demonstrated that immunization of CEA transgenic mice with bone marrow-derived mature dendritic cells (DC) loaded with anti-idiotype 3H1 or CEA could reverse CEA unresponsiveness and result in the induction of CEA-specific immune responses and the rejection of CEA-transfected MC-38 colon carcinoma cells, C15 (Saha et al., 2004). To improve the antigen delivery into DCs, CEA conjugated to a protein-transduction domain, human immunodeficiency virus transactivating Tat was utilized. Furthermore, the truncated non-glycosylated CEA from Escherichia coli was purified to overcome the safety concerns and immunosuppressive functions associated with the native CEA protein.CEA-specific T cell proliferation and cytotoxic T cell responses were enhanced significantly in mice immunized with Tat-CEA-pulsed DCs [DC (Tat-CEA)] compared with those immunized with CEA-pulsed DCs [DC (CEA)]. T helper type 1 responses were more prominent in the DC (Tat-CEA) immunized mice whose splenocytes secreted more interferon-gamma and less interleukin-4 than those from DC (CEA) immunized mice. In vivo, the DC (Tat-CEA) vaccine delayed tumour growth significantly and prolonged survival of tumour-bearing mice (Bae et al., 2009).
References

CEACAM3