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caf1

Gene Name caf1
Sequence Strain (Species/Organism) Yersinia pestis
VO ID VO_0011017
NCBI Protein GI 48621
Other Database IDs CDD:286355
GOA:P26948
InterPro: IPR008966
InterPro: IPR015335
PDB: 1P5U
PDB: 1P5V
PDB: 1Z9S
PDB: 3DOS
PDB: 3DPB
PDB: 3DSN
UniProtKB/UniProt: P26948
Taxonomy ID 632
Gene Strand (Orientation) ?
Protein Name F1 capsule antigen
Protein pI 4.63
Protein Weight 16931.51
Protein Length 223
Protein Note Caf1 Capsule antigen; pfam09255
Protein Sequence
>CAA43966.1 F1 capsule antigen [Yersinia pestis]
MKKISSVIAIALFGTIATANAADLTASTTATATLVEPARITLTYKEGAPITIMDNGNIDTELLVGTLTLG
GYKTGTTSTSVNFTDAAGDPMYLTFTSQDGNNHQFTTKVIGKDSRDFDISPKVNGENLVGDDVVLATGSQ
DFFVRSIGSKGGKLAAGKYTDAVTVTVSNQ

Molecule Role Protective antigen
Molecule Role Annotation Vaccination of mice with deF1 DNA conferred protection against subcutaneous infection with the virulent Y. pestis Kimberley53 strain, even at challenge amounts as high as 4,000 50% lethal doses (Grosfeld et al., 2003).
Related Vaccines(s) Y. pestis DNA vaccine encoding dfF1 Protein
References