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peb1A
Gene Name	peb1A
Sequence Strain (Species/Organism)	Campylobacter jejuni
VO ID	VO_0011045
NCBI Protein GI	112360246
3D structure: PDB ID	2V25
Other Database IDs	CDD:183381 EnsemblGenomes-Gn:Cj0921c EnsemblGenomes-Tr:CAL35041 GOA:Q0P9X8 InterPro: IPR001638 InterPro: IPR018313 PDB: 2V25
Taxonomy ID	192222
Gene Strand (Orientation)	?
Protein Name	aspartate/glutamate-binding ABC transporter protein
Protein pI	8.53
Protein Weight	27458.45
Protein Length	390
Protein Note	bifunctional adhesin/ABC transporter aspartate/glutamate-binding protein; Reviewed
Protein Sequence	>CAL35041.1 aspartate/glutamate-binding ABC transporter protein [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819] MVFRKSLLKLAVFALGACVAFSNANAAEGKLESIKSKGQLIVGVKNDVPHYALLDQATGEIKGFEVDVAK LLAKSILGDDKKIKLVAVNAKTRGPLLDNGSVDAVIATFTITPERKRIYNFSEPYYQDAIGLLVLKEKKY KSLADMKGANIGVAQAATTKKAIGEAAKKIGIDVKFSEFPDYPSIKAALDAKRVDAFSVDKSILLGYVDD KSEILPDSFEPQSYGIVTKKDDPAFAKYVDDFVKEHKNEIDALAKKWGL
Molecule Role	Protective antigen
Molecule Role Annotation	Chitosan-DNA vaccines were prepared by embedding pcDNA3.1(+)-cadF and pcDNA3.1(+)-peblA with chitosan respectively. The mice immunized with chitosan-DNA vaccines have generated high levels of IgA and IgG from the sera and IgA from the intestinal secretions and the P/N value went up to 20.58, 30.13 and 6.87 respectively. The chitosan-DNA vaccines induced strongest level of protection in BALB/c mice against challenge with C. jejuni HS:19 strain and the protective efficacies was 93.70 (Zheng et al., 2007).
Related Vaccines(s)	C. jejuni DNA vaccine pcDNA3.1(+)-peblA
References

peb1A