VIOLIN: Vaccine Investigation and Online Information Network

fspA2
Gene Name	fspA2
Sequence Strain (Species/Organism)	Campylobacter jejuni
VO ID	VO_0011049
NCBI Protein GI	116292677
Taxonomy ID	197
Gene Strand (Orientation)	?
Protein Name	FspA2
Protein pI	5.78
Protein Weight	15654.3
Protein Length	187
Protein Note	sigma 28 regulated; Campylobacter jejuni-specific virulence factor that is secreted through the flagella filament
Protein Sequence	>ABJ97654.1 FspA2 [Campylobacter jejuni] MKIDTLTKNFSNYQTQINKNNDLASNVHSDNVVKIQISDEARSLSQANSKNEKEYEIKVSQEKIENHKDQ NSIQSSKGGGNPALEALIAKLAEILAKIAELTQKMTNANEQMKTTFQKQIDVLISQADVIQAQIQELQSQ QA
Molecule Role	Protective antigen
Molecule Role Annotation	Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model. Immunization with FspA2 provided 38.4% (without adjuvant) or 47.2% (with adjuvant) protection against disease from homologous challenge with CG8486 (Baqar et al., 2008).
Related Vaccines(s)	C. jejuni FspA2 protein vaccine
References