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gatC

Gene Name gatC
Sequence Strain (Species/Organism) Chlamydophila abortus
VO ID VO_0011057
NCBI Protein GI 62184917
Other Database IDs CDD:178810
Taxonomy ID 218497
Gene Strand (Orientation) ?
Protein Name aspartyl/glutamyl-tRNA amidotransferase subunit C
Protein pI 4.07
Protein Weight 10718.23
Protein Length 196
Protein Note aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; PRK00034
Protein Sequence
>YP_219702.1 aspartyl/glutamyl-tRNA amidotransferase subunit C [Chlamydophila abortus S26/3]
MTQPYVTREDIILLAKSSALELSEEFIQEYESSLNEVIKTMAASIAMDVTDVVIEVGLSHVISPEDLRED
IVASSFSREEFLTNVPESLGGLVKVPTVIK

Molecule Role Protective antigen
Molecule Role Annotation Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #2, gatC) was found to be protective. Three of the clones (CP #1–3) elicited protection that was statistically higher than the unvaccinated control, which has high variance (Stemke-Hale et al., 2005).
Related Vaccines(s) C. abortus DNA vaccine encoding GatA/GatB , C. abortus DNA vaccine encoding GatC
References