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RplF

Gene Name RplF
Sequence Strain (Species/Organism) Chlamydia muridarum str. Nigg
VO ID VO_0010892
NCBI Gene ID 1246168
NCBI Protein GI 497917443
Locus Tag TC_RS04070
Genbank Accession AE002160
Protein Accession WP_010231599
Taxonomy ID 243161
Gene Starting Position 941594
Gene Ending Position 942145
Gene Strand (Orientation) -
Protein Name 50S ribosomal protein L6
Protein pI 10.64
Protein Weight 18060.75
Protein Length 183
Protein Note ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
DNA Sequence 
>NC_002620.2:941594-942145 Chlamydia muridarum Nigg, complete genome
TCTATTTTTTACCAGTTTTCGCTGCTTTTCCAGCCTTACGACGTACATATTCGTTTTCGTAACGAATTCC
TTTACCTTTGTATGGCTCTGGAGGGCGTTTTGCACGAACACAAGCCGCAAATTCTCCTACCAACTGCTTG
TTGATACCTTTGATGGAGATCAATGTGTTCTTCTCAACAGAGACTTCCAATCCTGTAGGAATAGGCATTT
TTGTTGGATGGGAAACCCCTATCGATAAATCTAAGAAGGACCCCTGTACCGAAGCTCTGAATCCAACTCC
GATCATTTCTAAACGTTTTTCAAATCCAAGGTGGACACCTTTGACCATATTTGCTATCAAAGCCCAATAA
AGCCCTTGCATACGACCAGGTCTGTCTATAATGTGAGCTGCGGGAGAAACAAACACCTCATTACCTTTAA
CGGCAATCTCAACTTCTTTAGCCAACACCTGTGTCAAAGACCCTTTAGGACCTTTTACTGAGATTTCATC
ATTTTGAATAGAGACCTCTACGCCTTGAGGAAGTACAATAGGGTCTCGAGCTTTACGAGACA
Protein Sequence 
>WP_010231599.1 50S ribosomal protein L6 [Chlamydia muridarum]
MSRKARDPIVLPQGVEVSIQNDEISVKGPKGSLTQVLAKEVEIAVKGNEVFVSPAAHIIDRPGRMQGLYW
ALIANMVKGVHLGFEKRLEMIGVGFRASVQGSFLDLSIGVSHPTKMPIPTGLEVSVEKNTLISIKGINKQ
LVGEFAACVRAKRPPEPYKGKGIRYENEYVRRKAGKAAKTGKK
Molecule Role Protective antigen
Molecule Role Annotation Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection. In addition, RplF was able to engender protective immunity against challenge with C. muridarum (Yu et al., 2009).
Related Vaccines(s) C. muridarum RplF protein vaccine
References