VIOLIN: Vaccine Investigation and Online Information Network

Ssb
Gene Name	Ssb
Sequence Strain (Species/Organism)	Chlamydophila pneumoniae CWL029
VO ID	VO_0010896
NCBI Gene ID	894901
NCBI Protein GI	15618301
Locus Tag	CPn0386
Genbank Accession	AE001363
Protein Accession	NP_224586
Taxonomy ID	115713
Gene Starting Position	434042
Gene Ending Position	434524
Gene Strand (Orientation)	-
Protein Name	single-stranded DNA-binding protein
Protein pI	5.29
Protein Weight	16434.22
Protein Length	160
Protein Note	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
DNA Sequence	>NC_000922.1:434042-434524 Chlamydophila pneumoniae CWL029 chromosome, complete genome ATTAAAAAGGAACATCTTCACAGACATACTGCTGTTCTTGACCATAACCAGCATACATATCTTTATCTTT AATAGCTTCTGCGTCCAGTGCTTCACCTTCAAACCCTACGGATACAGATTCATATCCCACTTGCTGATGA TTGTCTTCTAAAGATGGAGAACGGCTGCCTTCATTGCGACCGAAAGGACTGAATTTCAAAGAATCTACAC TAATCACTAAAGAAGATTGCGGTGAACCATCTTTGCTCATGTAACTCTCTACAGAGATATCGCCAGCAAC AATGACTCCTGAGCCTTTCTTCAAGTAAGGAAGCATCTTATCATAGCGATTGTGCCAAATATTGCATTTG CACCAAACAGTTTCATCTTTCATTCCAACTCGAGTCTTCACTCCCAGTCTCAGAGTGATCACACGTTTTC CTTTGGAAGTCATTCGCTCTTCAGGATCTGCTCCAAGGTAACCAGCAAAATGCCCAAACATCA
Protein Sequence	>NP_224586.1 single-stranded DNA-binding protein [Chlamydia pneumoniae CWL029] MMFGHFAGYLGADPEERMTSKGKRVITLRLGVKTRVGMKDETVWCKCNIWHNRYDKMLPYLKKGSGVIVA GDISVESYMSKDGSPQSSLVISVDSLKFSPFGRNEGSRSPSLEDNHQQVGYESVSVGFEGEALDAEAIKD KDMYAGYGQEQQYVCEDVPF
Molecule Role	Protective antigen
Molecule Role Annotation	Mice vaccinated with candidate gene ssb showed significant reduction of spleen chlamydial loads as compared to naïve, non-protected control mice (p ≤ 0.048). This resulted in the ability of ssb to mediate a modest, but significant level of protection in an inbred A/J mouse respiratory challenge model (Li et al., 2006).
Related Vaccines(s)	C. pneumoniae DNA vaccine encoding Ssb
References

Ssb