VIOLIN: Vaccine Investigation and Online Information Network

gp55
Gene Name	gp55
VO ID	VO_0010899
NCBI Protein GI	1763691
Other Database IDs	CDD:292945
Taxonomy ID	11096
Gene Strand (Orientation)	?
Protein Name	glycoprotein
Protein pI	6.6
Protein Weight	38891.77
Protein Length	452
Protein Note	Pestivirus envelope glycoprotein E2; pfam16329
Protein Sequence	>AAB39835.1 glycoprotein, partial [Classical swine fever virus] VQGVVWLLLVTGAQGRLACKEDYRYAISSTDEIGLLGAGGLTTTWKEYNHDLQLNDGTVKASCVAGSFKV TALNVVSRRYLASLHKKALPISVTFELLFDGTNPSTEEMEDDLRSGLCPFDTSPVVKGKYNTTLLNGSAF YLVCPIGWTGVIECTAVSPTTLRTEVVKTFRRDKPFPHRMDCVTTTVENEDLFYCKLGGNWTCVKGEPVV YTGGVVKQCRWCGFDFDGPDGLPHYPIGKCILANETGYRIVDSTDCNRDGVVISTEGSHECLIGNTAVKV HASDERLGPMPCRPKEIVSSAGPVMKTSCTFNYTKTLKNRYYEPRDSYFRQYMLKGEYQYWFDLDATDRH SDYFAEFVVLVVVALLRGRYVLWLIVTYAVL
Molecule Role	Protective antigen
Molecule Role Annotation	Intramuscular vaccination of pigs with immunoaffinity-purified E1 (gp55) in a double water-oil emulsion elicited high titers of neutralizing antibodies between 2 and 4 weeks after vaccination at the lowest dose tested (20 micrograms). The vaccinated pigs were completely protected against intranasal challenge with 100 50% lethal doses of HCV (Classical swine fever virus) strain Brescia (Hulst et al., 1993).
Related Vaccines(s)	Classical swine fever virus E1 protein vaccine
References