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3-1E

Gene Name 3-1E
Sequence Strain (Species/Organism) Eimeria tenella
VO ID VO_0011066
NCBI Protein GI 126362934
Other Database IDs CDD:320770
CDD:238085
Taxonomy ID 5802
Gene Strand (Orientation) ?
Protein Name sporozoite antigen 3-1E
Protein pI 3.96
Protein Weight 17761.05
Protein Length 237
Protein Note Profilin binds actin monomers, membrane polyphosphoinositides such as PI(4,5)P2, and poly-L-proline. Profilin can inhibit actin polymerization into F-actin by binding to monomeric actin (G-actin) and terminal F-actin subunits, but - as a regulator of the...; cl00123
Protein Sequence
>ABO10495.1 sporozoite antigen 3-1E, partial [Eimeria tenella]
MGEEADTQAWDTSVKEWLVDTGKVYAGGIASIADGCRLFGAAIDNGEDAWSQLVKTGYQIEVLQEDGSST
QEDCDEAETLRQAIVDGRAPNGVYIGGIKYKLAEVKRDFTYNDQNYDVAILGKNKGGGFLIKTPNDNVVI
ALYDEEKEQNKADALTTALAFAEYLYQGGF

Molecule Role Protective antigen
Molecule Role Annotation The Eimeria tenella antigen gene (3-1E) and chicken interferon gamma gene (ChIFN-gamma) were subcloned into the mammalian expression vector proVAX forming the plasmids proE and prol. After challenge the proIE-vaccinated chickens showed protective immunity as demonstrated by significantly reduced oocyst shedding (Xu et al., 2006).
Additional Molecule Role Protective antigen
Related Vaccines(s) E. tenella DNA vaccine proIE
References