VIOLIN: Vaccine Investigation and Online Information Network

Env from strain FRA
Gene Name	Env from strain FRA
Sequence Strain (Species/Organism)	Feline leukemia virus
VO ID	VO_0011068
NCBI Gene ID	1491868
NCBI Protein GI	9630709
Locus Tag	FeLVgp2
Genbank Accession	AF052723
Protein Accession	NP_047256
Taxonomy ID	11768
Gene Starting Position	5987
Gene Ending Position	7915
Gene Strand (Orientation)	?
Protein Name	Env polyprotein
Protein pI	8.36
Protein Weight	67586.88
Protein Length	642
DNA Sequence	>NC_001940.1:5987-7915 Feline leukemia virus, complete genome GATGGAAAGTCCAACGCACCCAAAACCCTCTAAAGATAAGACTCTCTCGTGGAACTTAGCGTTTCTGGTG GGGATCTTATTCACAATAGACATAGGAATGGCCAATCCTAGTCCACACCAAATATATAATGTAACTTGGG TAATAACCAATATGCAAACTAACACCCAAGCTAATGCCACCTCTATGTTAGGAACCTTAACCGATGCCTA CCCTACCCTACATGTTGACCTATGTGACCTAGTGGGAGACACCTGGGAACCTATAGTCCTAGATCCAACC AATGTAAAACACGGGGCACGTTACTCCTCCTCAAAGTATGGATGTAAAACTACAGATAGAAAAAAACAGC AACAAACATACCCCTTTTACGTCTGCCCCGGACATGCCCCCTCGCTGGGGCCAAAGGGAACACATTGTGG AGGGGCACAAGATGGGTTTTGTGCCGCATGGGGATGTGAGACCACCGGAGAAGCTTGGTGGAAGCCCTCC TCCTCATGGGACTATATCACAGTAAAAAGAGGGAGTAGTCAGGACAATAGCTGTGAGGGAAAATGCAACC CCCTGATTTTGCAGTTCACCCAGAAGGGAAGACAAGCCTCTTGGGACGGACCTAAGATATGGGGATTGCG ACTATACCGTACAGGATATGACCCTATCGCCTTATTCACGGTGTCCCGGCAGGTGTCAGCCATTACGCCG CCTCAGGCAATGGGACCAAACCTAGTCTTACCTGATCAAAAACCCCCATCCAGACAATCCCAAACAGGGT CCAAAGTGGCGACCCAGAGGCTCCAAACGACTGAAAGCGCCCCAAGGTCTGTTGCCCCCACCACCGTGGG TCCCAAACGGATTGGGACCGGAGATAGGTTAATAAATTTAGTACAAGGGACATACCTAGCCTTAAATGCC ACCGACCCCAACAAAACTAAAGACTGTTGGCTCTGCCTGGTTTCTCGACCACCCTATTACGAAGGGATTG CAATCTTAGGTAACTACAGCAACCAAACAAACCCCCCCCCATCCTGCCTATCTACTCCGCAACACAAACT GACCATATCTGAAGTATCAGGGCAAGGACTGTGCATAGGGACTGTTCCTAAGACCCACCAGGCTTTGTGC AATGAGACACAACAGGGACATACAGGGGCGCACTATCTAGCCGCCCCCAATGGCGCCTATTGGGCCTGTA ACACTGGACTCACCCCATGCATTTCCATGGCGGTGCTCAATTGGACCTCTGATTTTTGTGTCTTAATCGA ATTATGGCCCAGAGTGACTTACCATCAACCCGAATATGTGTACACACATTTTGCCAAAGCTGTCAGGTTC CGAAGAGAACCAATATCACTAACTGTTGCCCTCATGTTGGGAGGACTCACTGTAGGGGGCATAGCCGCGG GGGTCGGAACAGGGACTAAAGCCCTCCTTGAAACAGCCCAGTTCAGACAACTACAAATGGCCATGCACAC AGACATCCAGGCCCTAGAAGAGTCAATTAGTGCCTTAGAAAAGTCCCTGACCTCCCTTTCTGAAGTAGTC TTACAAAACAGACGGGGCCTAGATATTCTATTCTTACAAGAGGGAGGGCTCTGTGCCGCATTAAAAGAAG AATGTTGCTTCTATGCGGATCACACCGGACTCGTCCGAGACAATATGGCTAAATTGAGAGAAAGACTAAA ACAGCGGCAACAACTGTTTGACTCCCAACAGGGATGGTTTGAAGGATGGTTCAACAAGTCCCCCTGGTTC ACAACCTTAATTTCCTCCATTATGGGCCCCTTACTAATCCTACTCCTAATTCTCCTCTTCGGCCCATGCA TCCTTAACAGATTAGTACAATTCGTAAAAGACAGAATATCTGTGGTACAAGCCTTAATTTTAACCCAACA GTACCAACAGATAAAGCAATACGATCCGGACCGACCATG
Protein Sequence	>NP_047256.1 Env polyprotein [Feline leukemia virus] MESPTHPKPSKDKTLSWNLAFLVGILFTIDIGMANPSPHQIYNVTWVITNMQTNTQANATSMLGTLTDAY PTLHVDLCDLVGDTWEPIVLDPTNVKHGARYSSSKYGCKTTDRKKQQQTYPFYVCPGHAPSLGPKGTHCG GAQDGFCAAWGCETTGEAWWKPSSSWDYITVKRGSSQDNSCEGKCNPLILQFTQKGRQASWDGPKIWGLR LYRTGYDPIALFTVSRQVSAITPPQAMGPNLVLPDQKPPSRQSQTGSKVATQRLQTTESAPRSVAPTTVG PKRIGTGDRLINLVQGTYLALNATDPNKTKDCWLCLVSRPPYYEGIAILGNYSNQTNPPPSCLSTPQHKL TISEVSGQGLCIGTVPKTHQALCNETQQGHTGAHYLAAPNGAYWACNTGLTPCISMAVLNWTSDFCVLIE LWPRVTYHQPEYVYTHFAKAVRFRREPISLTVALMLGGLTVGGIAAGVGTGTKALLETAQFRQLQMAMHT DIQALEESISALEKSLTSLSEVVLQNRRGLDILFLQEGGLCAALKEECCFYADHTGLVRDNMAKLRERLK QRQQLFDSQQGWFEGWFNKSPWFTTLISSIMGPLLILLLILLFGPCILNRLVQFVKDRISVVQALILTQQ YQQIKQYDPDRP
Molecule Role	Protective antigen
Molecule Role Annotation	Study describes experiments which demonstrate that the vaccine, (EURIFEL FeLV; Merial) that expresses the FeLV env and gag protective genes, is effective against any oronasal FeLV challenge. The protection was shown to be solid against an oronasal challenge one year after the initial vaccination, and was effective against a very severe 'in-contact' challenge (Poulet et al., 2003).
Related Vaccines(s)	EURIFEL FeLV
References

Env from strain FRA