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M Segment

Gene Name M Segment
Sequence Strain (Species/Organism) Hantaan virus
VO ID VO_0011090
NCBI Protein GI 1389703
Other Database IDs CDD:144961
Taxonomy ID 1980471
Gene Strand (Orientation) ?
Protein Name M polyprotein
Protein pI 6.21
Protein Weight 12313.73
Protein Length 172
Protein Note Hantavirus glycoprotein G2; pfam01561
Protein Sequence
>AAB02907.1 M polyprotein, partial [Hantaan orthohantavirus]
TPLTPVWNDNAHGVGSVPMHTDLELDFSLTSSSKYTYRRKLTNPLEEAQSVDLHIEIEEQTIGVDVHALG
HWFDGRLNLKTSFHCYGACTKYDYPWHTAKCHYERDYQ

Molecule Role Protective antigen
Molecule Role Annotation Researchers vaccinated hamsters with a vaccinia virus-vectored vaccine expressing the M and the S segments of Hantaan (HTN) virus and challenged them with HTN, Seoul (SEO), or Puumala (PUU) virus. Study found that vaccinated hamsters, challenged with HTN or SEO virus, were neither viremic nor had evidence of virus in their lungs or kidneys (Chu et al., 1995).
References