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HTNVsSgp1

Gene Name HTNVsSgp1
Sequence Strain (Species/Organism) Hantaan orthohantavirus
VO ID VO_0011091
NCBI Gene ID 2943078
NCBI Protein GI 38371711
Locus Tag HTNVsSgp1
Genbank Accession M14626
Protein Accession NP_941977
Taxonomy ID 1980471
Segment No segment S
Gene Starting Position 36
Gene Ending Position 1325
Gene Strand (Orientation) +
Protein Name hypothetical protein
Protein pI 7.11
Protein Weight 45859.21
Protein Length 429
DNA Sequence 
>NC_005218.1:36-1325 Hantaan virus, complete genome
GATGGCAACTATGGAGGAATTACAGAGGGAAATCAATGCCCATGAGGGTCAATTAGTGATAGCCAGGCAG
AAGGTGAGGGATGCAGAAAAACAGTATGAAAAGGATCCAGATGAGTTGAACAAGAGAACATTAACTGACC
GAGAGGGCGTTGCAGTATCTATCCAGGCAAAAATTGATGAGTTAAAAAGGCAACTGGCAGATAGGATTGC
AACTGGGAAAAACCTTGGGAAGGAACAAGATCCAACAGGGGTGGAGCCTGGAGACCATCTGAAAGAGAGG
TCAATGCTCAGTTATGGTAATGTGCTGGATTTAAACCATTTGGATATTGATGAACCTACAGGACAGACAG
CAGACTGGCTGAGCATCATCGTCTATCTTACATCCTTTGTCGTCCCGATACTTCTGAAAGCTCTGTATAT
GTTGACAACAAGGGGGAGGCAAACTACCAAGGATAATAAAGGGACCCGGATTCGATTTAAGGATGATAGC
TCGTTCGAGGATGTTAACGGTATCCGGAAACCAAAACATCTTTACGTGTCCTTGCCAAATGCACAGTCAA
GCATGAAGGCAGAAGAGATTACACCTGGTAGATATAGAACAGCAGTCTGTGGGCTCTACCCTGCACAGAT
TAAGGCACGGCAGATGATCAGTCCAGTTATGAGTGTAATTGGTTTTCTAGCATTAGCAAAGGACTGGAGT
GATCGTATCGAACAATGGTTAATTGAACCTTGCAAGCTTCTTCCAGATACAGCAGCAGTTAGCCTCCTTG
GTGGTCCTGCAACAAACAGGGACTACTTACGGCAGCGGCAAGTGGCATTAGGCAATATGGAGACAAAGGA
GTCAAAGGCTATACGCCAGCATGCAGAAGCAGCTGGCTGTAGCATGATTGAAGATATTGAGTCACCATCA
TCAATATGGGTTTTTGCTGGAGCACCAGACCGTTGTCCACCAACATGTTTGTTTATAGCAGGTATTGCTG
AGCTTGGGGCATTTTTTTCCATCCTGCAGGACATGCGAAATACAATCATGGCATCTAAGACAGTTGGAAC
ATCTGAGGAGAAGCTACGGAAGAAATCATCATTTTATCAGTCCTACCTCAGAAGGACACAATCAATGGGG
ATACAACTAGGCCAGAGAATTATTGTGCTCTTCATGGTTGCCTGGGGAAAGGAGGCTGTGGACAACTTCC
ACTTAGGGGATGATATGGATCCTGAGCTAAGGACACTGGCACAGAGCTTGATTGATGTCAAAGTGAAGGA
AATCTCCAACCAAGAGCCTTTGAAACTCTA
Protein Sequence 
>NP_941977.1 hypothetical protein [Hantaan orthohantavirus]
MATMEELQREINAHEGQLVIARQKVRDAEKQYEKDPDELNKRTLTDREGVAVSIQAKIDELKRQLADRIA
TGKNLGKEQDPTGVEPGDHLKERSMLSYGNVLDLNHLDIDEPTGQTADWLSIIVYLTSFVVPILLKALYM
LTTRGRQTTKDNKGTRIRFKDDSSFEDVNGIRKPKHLYVSLPNAQSSMKAEEITPGRYRTAVCGLYPAQI
KARQMISPVMSVIGFLALAKDWSDRIEQWLIEPCKLLPDTAAVSLLGGPATNRDYLRQRQVALGNMETKE
SKAIRQHAEAAGCSMIEDIESPSSIWVFAGAPDRCPPTCLFIAGIAELGAFFSILQDMRNTIMASKTVGT
SEEKLRKKSSFYQSYLRRTQSMGIQLGQRIIVLFMVAWGKEAVDNFHLGDDMDPELRTLAQSLIDVKVKE
ISNQEPLKL
Molecule Role Protective antigen
Molecule Role Annotation Passive transfer of spleen cells from mice immunized with rNP (HTNVsSgp1) conferred partial protection or prolongation of time to death from fatal Hantaan virus infection in suckling mice which were challenged with Hantaan virus at 40 LD50 (survival rate: 43%) or 4 LD50 (survival rate: 43%) (Yoshimatsu et al., 1993).
References