VIOLIN: Vaccine Investigation and Online Information Network

HA from Influenza A virus (A/WSN/1933(H1N1))
Gene Name	HA from Influenza A virus (A/WSN/1933(H1N1))
Sequence Strain (Species/Organism)	Influenza A virus (A/WSN/1933(H1N1))
VO ID	VO_0011113
NCBI Protein GI	324200
Other Database IDs	CDD:278910
Taxonomy ID	382835
Gene Strand (Orientation)	?
Protein Name	hemagglutinin precursor
Protein pI	7.02
Protein Weight	61355.76
Protein Length	650
Protein Note	signal peptide
Protein Sequence	>AAA43209.1 hemagglutinin precursor [Influenza A virus (A/WSN/1933(H1N1))] MKAKLLVLLYAFVATDADTICIGYHANNSTDTVDTIFEKNVAVTHSVNLLEDRHNGKLCKLKGIAPLQLG KCNITGWLLGNPECDSLLPARSWSYIVETPNSENGACYPGDFIDYEELREQLSSVSSLERFEIFPKESSW PNHTFNGVTVSCSHRGKSSFYRNLLWLTKKGDSYPKLTNSYVNNKGKEVLVLWGVHHPSSSDEQQSLYSN GNAYVSVASSNYNRRFTPEIAARPKVKDQHGRMNYYWTLLEPGDTIIFEATGNLIAPWYAFALSRGFESG IITSNASMHECNTKCQTPQGSINSNLPFQNIHPVTIGECPKYVRSTKLRMVTGLRNIPSIQYRGLFGAIA GFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAINGITNKVNSVIEKMNTQFTAVGKEFNNLEKRM ENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDLNVKNLYEKVKSQLKNNAKEIGNGCFEFYHKCDNE CMESVRNGTYDYPKYSEESKLNREKIDGVKLESMGVYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQ CRICI
Molecule Role	Protective antigen
Molecule Role Annotation	A nonpathogenic vector of the cytoplasmic domain of the VSV G protein and expressing influenza virus HA (derived from Influenza A virus (A/WSN/1933(H1N1))) provides complete protection from lethal influenza virus challenge after intranasal administration. A second vector with VSV G deleted and expressing HA (DeltaG-HA) is also protective and nonpathogenic and has the advantage of not inducing neutralizing antibodies to the vector itself (Roberts et al., 1999).
Related Vaccines(s)	Recombinant vesicular stomatitis virus encoding HA from Influenza A virus (A/WSN/1933(H1N1))
References

HA from Influenza A virus (A/WSN/1933(H1N1))