VIOLIN: Vaccine Investigation and Online Information Network

NA
Gene Name	NA
Sequence Strain (Species/Organism)	Influenza A virus (A/Aichi/2/1968(H3N2))
VO ID	VO_0011123
NCBI Protein GI	46401580
Other Database IDs	CDD:271235
Taxonomy ID	387139
Gene Strand (Orientation)	?
Protein Name	neuraminidase
Protein pI	6.7
Protein Weight	49574.86
Protein Length	546
Protein Note	synonym: Influenza A virus (A/Aichi/2/68(H3N2))
Protein Sequence	>BAD16642.1 neuraminidase [Influenza A virus (A/Aichi/2/1968(H3N2))] MNPNQKIITIGSVSLTIATVCFLMQIAILVTTVTLHFKQYECDSPASNQVMPCEPIIIERNITEIVYLNN TTIDKEKCPKVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDHGKCYQFALGQGTTL DNKHSNDTIHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGR LVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLSGSAQHVEECSC YPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDRSSNSNCRNPNNERGNQGVK GWAFDNGDDVWMGRTISKDLRSGYETFKVIGGWSTPNSKSQINRQVIVDSDNRSGYSGIFSVEGKSCINR CFYVELIRGRKQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
Molecule Role	Protective antigen
Molecule Role Annotation	The protective effect of neuraminidase (NA) was studied in a mouse protection test using isolated neuraminidase of A2/Aichi/68(H3N2) virus and the complete recombinant virus A/eq(Heq-1)-HK(N2) as antigens. Immunized mice were protected against A2/Aichi(H3N2) challenge virus; however, the protection rate was low in comparison to animals immunized with comparable amounts of the complete A2/68(H3N2) virus9 (Reichert and Mauler, 1975).
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