VIOLIN: Vaccine Investigation and Online Information Network

NA
Gene Name	NA
Sequence Strain (Species/Organism)	Influenza B virus (B/Ibaraki/2/85)
VO ID	VO_0011129
NCBI Protein GI	53829726
Other Database IDs	CDD:278493
Taxonomy ID	107411
Gene Strand (Orientation)	?
Protein Name	NA glycoprotein
Protein pI	7.54
Protein Weight	50164.23
Protein Length	538
Protein Note	Neuraminidase; pfam00064
Protein Sequence	>AAU94751.1 NA glycoprotein [Influenza B virus (B/Ibaraki/2/85)] MLPSTIQTLTLFLTSGGVLLSLYVSASLSYLLYSDILLKFSPKITAPTMTLDCANASNVQAVNRSATKEM TFLLPEPEWTYPRLSCQGSTFQKALLISPHRFGEARGNSAPLIIREPFIACGPKECKHFALTHYAAQPGG YYNGTREDRNKLRHLISVKLGKIPTVENSIFHMAAWSGSACHDGREWTYIGVDGPDSNALIKIKYGEAYT DTYHSYANNILRTQESACNCIGGDCYLMITDGSASGISKCRFLKIREGRIIKEIFPTGRVEHTEECTCGF ASNKTIECACRDNNYTAKRPFVKLNVETDTAEIRLMCTETYLDTPRPDDGSITGPCESNGDKGRGGIKGG FVHQRMASKIGRWYSRTMSKTERMGMELYVKYDGDPWTDSDALAPSGVMVSMKEPGWYSFGFEIKDKKCD VPCIGIEMVHDGGKKTWHSAATAIYCLMGSGQLLWDTVTGVDMAL
Molecule Role	Protective antigen
Molecule Role Annotation	Protection against a lethal influenza B virus infection was examined in BALB/c mice immunized with plasmid DNAs encoding hemagglutinin (HA), neuraminidase (NA and NB) and nucleoprotein (NP) from the B/Ibaraki/2/85 virus. Both HA and NA DNAs conferred complete protection against the lethal challenge in all the tested mouse strains (Chen et al., 2001).
Related Vaccines(s)	Influenza virus DNA vaccine encoding NA from Influenza B virus (B/Ibaraki/2/85)
References