VIOLIN: Vaccine Investigation and Online Information Network

HA
Gene Name	HA
Sequence Strain (Species/Organism)	Influenza A virus (A/Hawaii/01/1991(H3N2))
VO ID	VO_0011132
NCBI Protein GI	110313990
Other Database IDs	CDD:278910
Taxonomy ID	387158
Gene Strand (Orientation)	?
Protein Name	haemagglutinin
Protein pI	9.43
Protein Weight	35361.77
Protein Length	416
Protein Note	egg isolate
Protein Sequence	>ABG66978.1 haemagglutinin, partial [Influenza A virus (A/Hawaii/01/1991(H3N2))] QKLPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDSPHRILDGKNCTLIDAL LGDPHCDGFQNKEWDLFVERSKAYSNCYPYDVPDYASLRSLVASSGTLEFINEDFNWTGVAQSGESYACK RGSVKSFFSRLNWLHKSEYKYPALNVTMPNNGKFDKLYIWGVHHPSTDREQTSLYVRASGRVTVSTKRSQ QTVIPNIGSRPWVRGLSSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRTGKSSIMRSDAPIGTCSSE CITPNGSIPNDKPFQNVNRITYGACPRYVKQNTLKLATGMRNVPEKQTR
Molecule Role	Protective antigen
Molecule Role Annotation	A DNA vaccine encoding HA (from Influenza A virus (A/Hawaii/01/1991(H3N2))), NP and M1 (from a 1989 strain) protected ferrets better against challenge with the antigenic drift variant A/Georgia/03/93 than did the inactivated vaccine from the 1992-93 influenza season. Researchers report that the same DNA vaccine protected ferrets against a second, further divergent, drift variant (A/Johannesburg/33/94) (Donnelly et al., 1997).
References