VIOLIN: Vaccine Investigation and Online Information Network

NP
Gene Name	NP
Sequence Strain (Species/Organism)	Influenza A virus (A/chicken/Hubei/489/2004(H5N1))
VO ID	VO_0011137
NCBI Protein GI	55233233
Other Database IDs	CDD:278907
Taxonomy ID	298603
Gene Strand (Orientation)	?
Protein Name	nucleoprotein
Protein pI	9.66
Protein Weight	54661.59
Protein Length	586
Protein Note	Influenza virus nucleoprotein; pfam00506
Protein Sequence	>AAV48549.1 nucleoprotein [Influenza A virus (A/chicken/Hubei/489/2004(H5N1))] MASQGTKRSYEQMETGGERQNATEIRASVGRMVSGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSA FDERRNRYLEEHPSAGKDPKKTGGPIYRRRDGKWVRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWH SNLDDATSQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGE NGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACV YGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGT RVVPRGQLSTRGVQIASNENMEAMDSNTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPF ERATIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPIVPSFDMNNEGSYFFG DNAEEYDN
Molecule Role	Protective antigen
Molecule Role Annotation	Vaccination with ptPAs/NP derived from Influenza A virus (A/chicken/Hubei/489/2004(H5N1)) efficiently cleared the homologous H5N1 influenza virus in the infected lungs and induced partial cross-protection against heterologous, highly pathogenic H5N1 strains in mice (Luo et al., 2008).
Related Vaccines(s)	Influenza virus DNA vaccine encoding NP from Influenza A virus (A/chicken/Hubei/489/2004(H5N1)) , Influenza virus DNA vaccine pHA/NP147–155 encoding NP147-155
References