VIOLIN: Vaccine Investigation and Online Information Network

NS1
Gene Name	NS1
Sequence Strain (Species/Organism)	Japanese encephalitis virus
VO ID	VO_0011147
NCBI Protein GI	18418672
Other Database IDs	CDD:279316
Taxonomy ID	11072
Gene Strand (Orientation)	?
Protein Name	NS1 protein
Protein pI	8.12
Protein Weight	16884.93
Protein Length	218
Protein Note	isolated from porcine sera
Protein Sequence	>AAL68990.1 NS1 protein, partial [Japanese encephalitis virus] ELIIPHTIAGPRSKHNRREGYKTQNQGPWDENGIVLDFDYCPGTKVTITEDCGKRGPSIRTTTDSGKLIT DWCCRSCSLPPLRFRTENGCWYGMEIRPVRHDETTLVRSQVDAFNGEMIDPFQLGLLVMFLATQEVLRKR WTARLTIPAVL
Molecule Role	Protective antigen
Molecule Role Annotation	Balb/c mice and swine vaccinated with TK(-)/gG(-)/NS1(+) expressing NS1 protein of JEV could confer protective immunity against lethal challenge of the virulent PRV Ea strain and develop a good humoral and cellular immune response against JEV (Xu et al., 2004).
Related Vaccines(s)	Japanese encephalitis virus DNA vaccine encoding NS1 (pUSK-NS1) , Japanese encephalitis virus DNA Vaccine P-JEV , NYVAC-JEV- prM/E/ NS1
References