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F1-ATPase

Gene Name F1-ATPase
Sequence Strain (Species/Organism) Leishmania donovani
VO ID VO_0011154
NCBI Protein GI 722242
Other Database IDs CDD:304359
CDD:238540
CDD:278722
Taxonomy ID 5661
Gene Strand (Orientation) ?
Protein Name F1-ATPase beta subunit
Protein pI 4.18
Protein Weight 20953.9
Protein Length 292
Protein Note promastigotes of Leishmania donovani Sudan 1S maintained in liquid culture as a suspension
Protein Sequence 
>AAA73465.1 F1-ATPase beta subunit, partial (mitochondrion) [Leishmania donovani]
KVALVYGQMNEPPGARAGVAESAVTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQP
TLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLEC
ASRIMDPDVIDVDHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQ
Molecule Role Protective antigen
Molecule Role Annotation Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani. Results demonstrated that liposomal LD31 (ATP synthase alpha chain) reduced parasite burden by 74%-77% (Bhowmick and Ali, 2009).
Related Vaccines(s) L. donovani LD31 Protein Vaccine
References