VIOLIN: Vaccine Investigation and Online Information Network

Beta-tubulin
Gene Name	Beta-tubulin
Sequence Strain (Species/Organism)	Leishmania donovani
VO ID	VO_0011155
NCBI Protein GI	262233287
Other Database IDs	CDD:276956 CDD:240228
Taxonomy ID	5661
Gene Strand (Orientation)	?
Protein Name	beta tubulin
Protein pI	6.31
Protein Weight	37694.97
Protein Length	416
Protein Note	The beta-tubulin family; cd02187
Protein Sequence	>ACY38664.1 beta tubulin, partial [Leishmania donovani] ESAGGRYVPRAVLMDLEPGTMDSVRAGPYGQLFRPDNFIFGQSGAGNNWAKGHYTEGAELIDSVLDVCRK EAESCDCLQGFQLSHSLGGGTGSGMGTLLISKLREEYPDRIMMTFSVIPSPRVSDTVVEPYNTTLSVHQL VENSDESMCIDNEALYDICFRTLKLTTPTFGDLNHLVAAVMSGVTCCLRFPGQLNSDLRKLAVNLVPFPR LHFFMMGFAPLTSRGSHQYPGLSVAELTQQMFDAKNMMQAADPRHGRYLTASALFRGRMSTKEVDEQMLN VQNKNSSYFIEWIPNNIKSSICDIPPKGLKMSVTFIGNNTCIQEMFRRVGEQFTGMFRRKACLHWYTGEG MDE
Molecule Role	Protective antigen
Molecule Role Annotation	Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani. Results demonstrated that liposomal LD51 (beta-tubulin) reduced parasite burden by 72%-75% (Bhowmick and Ali, 2009).
Related Vaccines(s)	L. donovani Beta-tubulin Protein Vaccine
References