VIOLIN: Vaccine Investigation and Online Information Network

KMP-11
Gene Name	KMP-11
Sequence Strain (Species/Organism)	Leishmania donovani
VO ID	VO_0011157
NCBI Protein GI	7579896
Other Database IDs	CDD:281087
Taxonomy ID	5661
Gene Strand (Orientation)	?
Protein Name	KMP-11
Protein pI	7.09
Protein Weight	11872.82
Protein Length	150
Protein Note	Kinetoplastid membrane protein 11; pfam03037
Protein Sequence	>AAB33127.2 KMP-11 (kinetoplast) [Leishmania donovani] MATTYEEFSAKLDRLDQEFNRKMQEQNAKFFADKPDESTLSPEMREHYEKFERMIKEHTEKFNKKMHEHS EHFKQKFAELLEQQKAAQYPSK
Molecule Role	Protective antigen
Molecule Role Annotation	KMP-11 DNA vaccination alone in an experimental BALB/c mice model showed significant potential in terms of resolution of splenic and hepatic parasite burden against virulent LD challenge. KMP-11 DNA immunization significantly protects against L. donovani infection (Bhaumik et al., 2009).
Related Vaccines(s)	L. donovani DNA Vaccine encoding KMP-11 , SL3261-L. donovani
References