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PDI

Gene Name PDI
Sequence Strain (Species/Organism) Neospora caninum
VO ID VO_0011191
NCBI Gene ID 13441704
NCBI Protein GI 82568727
Other Database IDs CDD:240266
CDD:294274
CDD:239259
CDD:239280
CDD:239293
Taxonomy ID 29176
Gene Strand (Orientation) ?
Protein Name protein disulfide isomerase
Protein pI 4.86
Protein Weight 49740.77
Protein Length 538
Protein Note disulphide isomerase; Provisional
Protein Sequence 
>BAD67151.2 protein disulfide isomerase [Neospora caninum]
MRAGFSFVLLAVGLLATASVYCAAEEEAVTVLTASNFDDTLKNTEIVLVKFYAPWCGHCKRMAPEYEKAA
KILKEKGSKIMLAKVDATSETDIADKQGVREYPTLTLFRNQKPEKFTGGRTAEAIVEWIEKMTGPAVTEV
EGKPEEQVTKESPIAFVAELSSKDSDMAKLFEDVANESRQLGKFLAKYGVSDEKIYSLRYEEGTEPFTGK
TKDELKKFVDTESFPLLGPINAENFRKYIDRDLDLVWLCGTEKDFDEAKAAVREAAKKLRDTRSFVWLDT
DQFKGHAENALGITEFPGLVFQSKKGRFVLPEATSSLKDAAKISKFFEDVDAGKIERSLKSEPVPEKQDE
AVKVVVGKNFEEMVIQKDKDVMLEIYAPWCGYCKSFEPIYKEFAEKYKDVDHLVVAKMDGTANEAPLEEF
SWSSFPSIFFVKAGEKTPMKFEGSRTVEGLTEFINKHGSKPLKKDDKGEEL
Molecule Role Protective antigen
Molecule Role Annotation A 90% protection rate was achieved following intra-nasal vaccination with recNcPDI emulsified in cholera toxin employing the C57Bl/6 mouse cerebral infection model when challenged with Neospora caninum tachyzoites (Debache et al., 2010).
Related Vaccines(s) N. caninum NcPDI Protein Vaccine
References