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MUC1 |
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Gene Name |
MUC1 |
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Sequence Strain (Species/Organism) |
Homo sapiens |
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NCBI Gene ID |
4582
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NCBI Protein GI |
67189007
|
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Locus Tag |
RP11-263K19.2 |
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Genbank Accession |
AC234582 |
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Protein Accession |
NP_001018016 |
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Taxonomy ID |
9606
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Chromosome No |
1 |
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Gene Starting Position |
155185823 |
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Gene Ending Position |
155192914 |
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Gene Strand (Orientation) |
- |
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Protein Name |
transcript variant 14 |
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Protein pI |
6.67 |
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Protein Weight |
26222.24 |
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Protein Length |
264 |
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DNA Sequence |
>NC_000001.11:155185823-155192914 Homo sapiens chromosome 1, GRCh38.p12 Primary Assembly
GTTGGCGCAGTGGGAGACCACGTTTTATTCAGTCCAGTTCAGGATCCCCGCTATCTCAGGGCTCTCTGGG
CCAGTCCTCCTGGGAGCCCCCACCACAACACTTCCCAGGCATGAGCCCTCAGGGGCCCACATGAGCTTCC
ACACACTGAGAAGTGTCCGAGAAATTGGTGGGGCCTCTGAAGGAGGCTGTGAGCAGCCCACCTGAACTCC
CAGCTCACCAGCCCAAACAGGGTGCAGGGGCTCTGGCCCTGAAGAACCTGAGTGGAGTGGAATGGCACTG
GCTGGCCACTCAGCTCAGCGGGCGACGTGCCCCTACAAGTTGGCAGAAGTGGCTGCCACTGCTGGGTTTG
TGTAAGAGAGGCTGCTGCCACCATTACCTGCAGAAACCTGGGTGGAAGGAAAAGAGATCCAGGGTGAGGA
GCAAAAGGTACCTCCTAGAGCCCCTGGATGCCACCCCAGGCTGGGGTAATCAGTCCAGAGTCCTGGCCAG
CTCTCAAAGGGTTAATTCAGAGAGAGCACCTGCCACCCCACCAGCCAGGTGACTGTAAACAGGGCTGCCC
TCCTCCCTCTGCTCTCCTTCACTCCCTCTTCTTGGCTCTAATCAGCCCCCTTGTCCCTCCATTCTCTGCT
GTTCCAGCCTAAGGAGGTGTGTGTGTGTGTGTGTGTGTGTTTTGGGGGGCGGGGTGTATCTGTGTCTTTG
TAAAGCCGAGAGAGGGAGGTCTCCAGGAGGAGGAAAATAGGAGCAAGAAAACTAAACTCTCTCCTCCCCC
ACCTGGAGTGGTTTTCCAGCCTCAGGTGGCTGCAGTAATTATTTACTAGGTCCCATAGAGAAAGACCAGG
AGAGGAAGGAGGGAGCGTTCCTTGCTTCCTTGAAGCTCCCAAGAACCCCACTGGCACCCACGCTCACCTG
GTCTGCTGACACTTCTTCTTCTACCTGGGAAACCTCCCCCTATGCCAGCCTTTCTCGGTCTACCCTCCAT
TCCTAGGAGATGATTAGGGGCACAGAGGCTCACCCCTGGGACTCCTCGGGAAGGGCTCCCCTGGGCATAG
TGCTCCACCCATTTTGCCTCTGGGTGCAAAAAAGCAAAACAAAACAAAACTGCCACGGTGGCACCAGTTC
AGCCAGCGCCAGCCAGCATGAATGTGGACGGCCAATGATCTTTTAGGAATTCTGGCAGTGGGGCCACTCC
CTCTTGAGGGCCCCTTTCTTCCATAGTCTCCTCCCAGGCCTGTCCCCCAAAACTCCTCTGACCTCTGCCC
CTCATCCTTGCCAGGCCCTCCCCTGCTCACTTCACGCCACTTCTCACCTCTTCCAAGCTCTTTGGGTTTT
CCAAGTACCCCCTTCAGAATCCTTGCCCAGCCAAACCCTCTGCTTCCCCTGGCCTGTGGGGCCCAATCTC
ACCTTCTCATAGGGGCTACGATCGGTACTGCTAGGGGGCACATAGCGCCCATGGGTGTGGTAGGTGGGGT
ACTCGCTCATAGGATGGTAGGTATCCCGGGCTGGAAAGATGTCCAGCTGCCCGTAGTTCTTTCGGCGGCA
CTGACAGACAGCCTGGGGAGATAGGAGGTTATGGCAGGCCATGGAGTGCCTTCTACCGGGGGGCTCTGAT
CAGGGCCAGGGACTGCACTCACCAAGGCAATGAGATAGACAATGGCCAGCGCAACCAGAACACAGACCAG
CACCAGCAGCGCGATGCCCCAGCCTGGCACCCCAGCCCCAGACTGGGCAGAGAAAGGAAATGGCACATCA
CTCACTAAAAGGAAAAGCAGTGGTCAGGGCAGTCTCCCAGAGGAGGCGCCCCTCCCGCTGCCAGCACTAA
GGAAAGAGCGGGGACCCAGACACTGGAAGGAGAGGGGCCCCGGCATGGTGCTGGGCTGCAGCCAGGGAAG
TAGCCTCACCGCTGACGTCTGAGATCGTCAGGTTATATCGAGAGGCTGCTTCCGTTTTATACTGATTGAA
CTGTGTCTCCACGTCGTGGACATTGATGGTACCTTCTCGGAAGGCCAGAGTCAATTGTACCACCACAGAT
CCTGGCCTGGTCACAGGGAAATGGGCACTTCAGCCACGGGTCCCAGCTCTGGCTCAGCACTCTTCCCCCA
ACCTTAAGTGCACCAGTCCCTCCCTACGGTCATGACCACCACCCACCCTCCAACCACCACACTGGGTCCA
CACCCAGAACTGTACCTGAACTTAATATTGGAGAGGCCCAGAAAACCCCCTTGTTTATAAATCTGCAAAA
ACTGGGGTGAGAGGGAAAGGACTCAGGCTTGATGCAAAGGGTGTGGACAGTTCTGATGGCTGCTTCAGGG
GAGCATGGGGAAGGAAAGGCCGATACTCACCATTTCAGAAATGTCTCTCTGCAGCTCTTGGTAGTAGTCG
GTGCTGGGATCTTCCAGAGAGGAATTAAACTGGAGGTTTGAAATGTGAAAAGACAGGAAAAAGAAAGAGA
CCCCAGTAGACAACTGGGGAGAAGTGCTGTGATTGGAGGAGGTGAGAGGAGGTACCGTGCTATGGTGAGT
GCTACTGGCATCAGTCTTGGTGCTATGGCTGGCAAGGGTGGTAGGAGTATCAGAGTGGTGGCTGGGAATT
GAGAATGGAGTGCTCTTGCTGGCTGGGGTTGTGGTAGCCCTGGCAGAGGTGCCGTTGTGCACCAGAGTAG
AAGCTGAGCCTGATGCAGAGCCTGAGGCCGAGGTGACATTGTGGACTGGAGGGGCGGTGGAGCCCAAGGC
GGGCCTGTTGTCCGGGGCCGAGGTGACACCATGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTG
TCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGGGTGGAGCCCGGGGCCC
GCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGTGCGGTGGAGCCCGGGGCCGGCCTGGTGTC
CGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAG
GTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGTGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGT
GGACTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGG
GGCGGTGGAGCCCGGGGGCCGGCCTGGTGTCCGGTGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGA
GCCCGGAGCCGGTCTGTTGTCCGGGGCCGAGGTGACACCGTGTGCTGGAGTGTCGGTGGAGCCCGAGGCC
GGCCTGGTGTCCGGGGCCGAGGTGACACTGTGAGCTGGGCTGCGGGCGCGGTGGAGCCCGGGGCCGGCCT
GCTCTCTGTTTTAAATATACACCGTGGGCTGCGGGCGCGGTGGAGCCCGGGGACGGCCTGGTGTCCGGGG
CCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGAC
ACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCT
GGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGG
TGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGG
GGCCGGCCTGCTCTCCGGGGCCGAGGTGACACCGTGGGCTGCTCTCGCGGTGGAGCCCGGGGCCGGCCTG
CTCTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGG
CCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGAC
ACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCT
TGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGCGGGCGCGG
TGTAGCCCGGGGCGGGCCTTGTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGG
GGCGGGACTGGTGTCCGGGGCCGAGGTGACACCGTGGGTTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTG
GTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGCTCTCCGGGG
CCGAGGTGACACCGTGGGCTGCGGGCGCGGTGGAGCCCGGGGCCGGCCTGCTCTCCGGGGCCGAGGTGAC
ACCGTGGGCTGCGGGCGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCT
GGGGGCGCGGTGGAGCCCGGGCCAGAACTGCTTTCCGGGGCCGTGGTGACTCCGTGGGCTGCGGGCGCGG
TGGAGCCCGGGGCCGGCCTGCTCTCTGGGGCCGAGGTGACACCGTGGGCTGCGGGCGCGGTGGAGCCCGG
GGCGGAACTCTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGGGGGGGAGCCCGGGGCCGGCCTGGTG
TCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCTGGGGCCGGCCTGGTGTCCGGGGCC
GAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACAC
CGTGGGCTTGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGC
GGGCGCGGTGGAGCCCGGGGCGGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTG
GAGCCCGGGGCGGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGG
CCGGCCTGGTGTCCGGGGTCGAGGTGACACCGTGGGCTTGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGT
GTCTGGGGGGGCGGTGGAGCCGGGGCCGGCCTGGTGTCCGGGGTTGGAAAACTGGGCTGGGGGGGCGGTG
GAGCCCGGGGCCGGCAGGGGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGC
CGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTTGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTG
TCCGGGGCCGAGGTGACACCGTGGGCTGCGGGCGCGGTGGAGCCCGGGGCGGGCCTGGTGTCCGGGGCCG
AGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCGGGCCTGGTGTCCGGGGCCGAGGTGACACC
GTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTTGG
GGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGCGGGCGCGGTGG
AGCCCGGGTCCGTCCTTCTCTCCGAGGGCCGAGGTGACATCGTAGACTGCGGGCGCGGTGGAGCCCGGGT
CCGGCCTGCTCTCCGAGGCCGAGGTGACACCGTAGACTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGT
GTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGAACCGGCCTGGTGTCCGGGGCC
GAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGTGTCCGGGGCCGAGGTGACAC
CGTGGGCTTGGGGGGCGGTGGAGCCCGGGACCGACCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGC
GGGCGCGGTGGAGCCCGGGGCGGACCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTG
GAGCCCGGGGCGGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGG
CCGGCCTGGTGTCCGGGGCCGAGGTGACACCGTGGGCTTGGGGGGCGGTGGAGCCCGGGGCCGGCCTGGT
GTCCGGGGCCGAGGTGACACCGTGGGCTGGGGGGGCGGTGGAGCCCGGGGCTGGCTTGTTGTCCGGGGCT
GAGGTGACATCGTGGGCTGGCGGGGTGGTGGAGCCCAGGGCTGGCCTGGTGACTGGGACCGAGGTGACAT
CCTGTCCCCAGGTGGCAGCTGAACCTGAAGCTGGTTCCGTGGCCGGGGCCAGAGTGACATCCTGTCCCTG
AGTGGTGGAGGAGCCTGAACCGGGGCTGTGGCTGGAGAGTACGCTGCTGGTCATACTCACAGCATTCTTC
TCAGTAGAGCTGGGCACTGAACTTCTCTGGGTAGCCGAAGTCTCCTTTTCTCCACCTGGGGTAGAGCTTG
CATGACCAGAACCCGTAACAACTGTTGCGGGTTTAGGGGCTGTGGTAGCTGTAAGAAGTTAAAGTCATAG
GGTTGGGTCTTTATGAAGGAAAAATAAGAGCAAGAAGAAAATATAAGCTCTGGCCACCAGAGAAATAATA
CCAGGAGGACTGGGGAGTGGGCAGCCTCAGTAACCCCTGGGTTGGCCGCCTCCTTCCCTGCAGCAGCCTC
CTTCTCTCTGCCCATAGGCCTTGGCTCATGGCCCCTGCATTTCTTCCCCTCTTAAGCCTTCCCTCTCCCT
ACTCTCTTCCCCCTAGACTTCTCTACAGGACATTTGCTTGCCCCTGGTACCCACTCTCAGGGTTGGGGGC
AACTCTTCTCAGCCTGTCCTTAGCCTCTCCCTCCTTCTGGCACAGACAGGGCAGCCTCTGTCTGCAATTC
TTACCTTAACTTCATGGTGCCATCTGCCAGGGAGCAAAACCCACAGAAAGACCACGAAGACCACCTAAGC
AGGGCAGCCCACTCCCCACCTCGTGCCCCTCACCTGTAAGCACTGTGAGGAGCAGCAGCAGGAAGAAAGG
AGACTGGGTGCCCGGTGTCATGGTGGTGGTGAAATGGGTGGGGAGGGGGCAGAACAGATTCAGGCAGGCG
CTGGCTGCTTGAGAGGTGGAGC
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Protein Sequence |
>NP_001018016.1 mucin-1 isoform 2 precursor [Homo sapiens]
MTPGTQSPFFLLLLLTVLTATTAPKPATVVTGSGHASSTPGGEKETSATQRSSVPSSTEKNAFNSSLEDP
STDYYQELQRDISEMFLQIYKQGGFLGLSNIKFRPGSVVVQLTLAFREGTINVHDVETQFNQYKTEAASR
YNLTISDVSVSDVPFPFSAQSGAGVPGWGIALLVLVCVLVALAIVYLIALAVCQCRRKNYGQLDIFPARD
TYHPMSEYPTYHTHGRYVPPSSTDRSPYEKVSAGNGGSSLSYTNPAVAATSANL
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Molecule Role |
Protective antigen |
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Molecule Role Annotation |
Vaccination of wild-type mice with MUC1 RNA-transfected DC induced anti-MUC1 immune responses against MUC1-positive MC38/MUC1, but not MUC1-negative, tumor cells. Mice immunized with the transfected DC were protected against challenge with MC38/MUC1 tumor cells. Furthermore, mice with established MC38/MUC1 tumors were eliminated after receiving the vaccination (Koido et al., 2000). |
| Related Vaccines(s) |
Ad-sig-hMUC-1/ecdCD40L Vaccine
,
adenovirus-transfected autologous DC vaccine plus CIK cells
,
Anti-idiotype MUC-1 Monoclonal Antibody Vaccine
,
Autologous Dendritic Cell-Tumor Fusion Vaccine
,
Emepepimut-S Vaccine
,
Falimarev Vaccine
,
Fowlpox Virus Vaccine Vector
,
Globo H-GM2-Lewis-y-MUC1-32-mer-TF(c)-Tn(c)-KLH Conjugate Vaccine
,
Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine
,
Inalimarev Vaccine
,
Liposomal MUC1/PET-lipid A Vaccine
,
Lung metastasis DNA vaccine pCEP4-MUC1 encoding MUC1
,
Mammaglobin-A DNA Vaccine
,
MUC-1 Peptide Vaccine
,
MUC1 Antigen/SB AS-2 Vaccine
,
MUC1 Peptide-Poly-ICLC Vaccine
,
MUC1-KLH Conjugate Vaccine
,
MUC1-KLH Vaccine/QS21
,
MUC1-targeted Peptide GO-203-2C Vaccine
,
MVA-MUC1-IL2 Vaccine
,
PSA:154-163 Peptide Vaccine
,
Recombinant Human MUC1-Oxidized Polymannose-pulsed Autologous Dendritic Cell Vaccine
,
Recombinant Vaccinia DF3/MUC1 Vaccine
,
Recombinant Vaccinia-MUC-1 Vaccine
,
Recombinant Vaccinia-MUC1-B7 Vaccine
,
rF-MUC1(DF3)/TRICOM Vaccine
,
Synthetic MUC1 Peptide Vaccine
|
| References |
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