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TcpF

Gene Name TcpF
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
VO ID VO_0011272
NCBI Gene ID 2614504
NCBI Protein GI 15640854
Locus Tag VC0837
Genbank Accession AE003852
Protein Accession NP_230485
Other Database IDs GDB:5363132
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 898672
Gene Ending Position 899688
Gene Strand (Orientation) +
Protein Name toxin co-regulated pilus biosynthesis protein F
Protein pI 6.37
Protein Weight 35844.42
Protein Length 338
Protein Note similar to SP:P29488 GB:L01623 PID:155281 PID:155284 PID:48417; identified by sequence similarity; putative
DNA Sequence
>NC_002505.1:898672-899688 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete sequence
TATGAGATATAAAAAAACCTTAATGTTATCAATCATGATTACATCATTTAACTCATTTGCATTTAATGAT
AATTATAGTTCAACCAGTACGGTTTATGCTACGTCTAATGAAGCTACGGATTCAAGGGGGAGTGAGCACC
TTAGATACCCTTATTTAGAGTGTATCAAAATCGGTATGAGTAGAGATTATCTTGAAAACTGTGTGAAAGT
ATCTTTTCCAACCTCTCAAGATATGTTTTATGACGCATACCCATCGACAGAATCTGACGGTGCTAAGACA
AGAACAAAAGAAGATTTCTCTGCTCGGCTTTTAGCTGGTGATTATGATAGTTTACAGAAATTGTATATAG
ATTTTTATCTTGCTCAAACGACTTTCGATTGGGAAATACCGACAAGGGATCAAATTGAGACACTAGTTAA
TTATGCTAATGAAGGTAAATTGTCTACGGCACTTAATCAAGAGTATATTACAGGTCGATTTCTTACAAAA
GAAAATGGTCGATATGATATTGTGAATGTTGGTGGTGTTCCAGATAATACTCCAGTTAAACTACCAGCTA
TTGTTTCTAAACGCGGACTAATGGGTACAACTTCTGTAGTTAATGCAATTCCCAATGAAATTTATCCTCA
TATCAAAGTTTATGAAGGGACTCTTAGTCGTTTAAAACCTGGTGGTGCAATGATCGCAGTATTAGAATAT
GACGTAAGTGAATTAAGTAAGCACGGGTATACCAATCTGTGGGATGTGCAGTTTAAGGTTCTTGTTGGAG
TTCCACATGCAGAAACAGGAGTTATCTATGACCCTGTTTATGAAGAAACTGTCAAACCATATCAGCCTAG
TGGCAACTTAACGGGTAAGAAGTTGTATAATGTATCTACAAATGACATGCATAATGGTTACAAGTGGTCA
AATACTATGTTCTCAAATTCTAATTATAAAACGCAAATATTATTAACTAAAGGAGATGGAAGTGGTGTGA
AACTGTATAGCAAAGCATATTCAGAGAACTTTAAATA

Protein Sequence
>NP_230485.1 toxin co-regulated pilus biosynthesis protein F [Vibrio cholerae O1 biovar El Tor str. N16961]
MRYKKTLMLSIMITSFNSFAFNDNYSSTSTVYATSNEATDSRGSEHLRYPYLECIKIGMSRDYLENCVKV
SFPTSQDMFYDAYPSTESDGAKTRTKEDFSARLLAGDYDSLQKLYIDFYLAQTTFDWEIPTRDQIETLVN
YANEGKLSTALNQEYITGRFLTKENGRYDIVNVGGVPDNTPVKLPAIVSKRGLMGTTSVVNAIPNEIYPH
IKVYEGTLSRLKPGGAMIAVLEYDVSELSKHGYTNLWDVQFKVLVGVPHAETGVIYDPVYEETVKPYQPS
GNLTGKKLYNVSTNDMHNGYKWSNTMFSNSNYKTQILLTKGDGSGVKLYSKAYSENFK

Molecule Role Protective antigen
Molecule Role Annotation Antibodies generated against TcpF are protective against experimental V. cholerae infection in the infant mouse cholera model (Kirn and Taylor, 2005).
References