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MOMP
Gene Name	MOMP
Sequence Strain (Species/Organism)	Chlamydophila psittaci 89/1051
VO ID	VO_0010925
NCBI Nucleotide GI	144544
NCBI Protein GI	144545
Protein Accession	AAA17396.1
Other Database IDs	CDD:279628
Taxonomy ID	83554
Gene Strand (Orientation)	?
Protein Name	major outer membrane protein
Protein pI	7.31
Protein Weight	41591.51
Protein Length	471
Protein Note	Chlamydia major outer membrane protein; pfam01308
DNA Sequence	>gi\|144544\|gb\|L04980.1\|CHTMOMPXX Chlamydia psittaci major outer membrane protein (MOMP) gene, complete cds CAATATAAGAAAGCCTTTACACTCTTCTACGAGGGTAATTCCAACTTATTCTAAGTGGCTAAGAAATAAA AATGTGTACAAAAATCTGATATCTTTTATTAGCAAGTATAAGGAGTTATTTTGAAATCTATGCCTGAAAA CAGTCTTTTTTCTTATCGTCTTTACTATAATAAGAAAAGTTTGTTATGTTTTCGAATAATGAACTGTATG TTCATGCTTAAGGCTGTTTTCACTTGCAAGACACTCCTCAAAGCCATTAATTGCCTACAGGATATCTTGT CTGGCTTTAACTTGGACGTGGTGCCGCCAGAAGAGCAAATTAGAATAGCGAGCACAAAAAGAAAAGATAC TAAGCATAATCTTTAGAGGTGAGTATGAAAAAACTCTTGAAATCGGCATTATTGTTTGCCGCTACGGGTT CCGCTCTCTCCTTACAAGCCTTGCCTGTAGGGAACCCAGCTGAACCAAGTTTATTAATCGATGGCACTAT GTGGGAAGGTGCTTCAGGAGATCCTTGCGATCCTTGCGCTACTTGGTGTGACGCCATTAGCATCCGCGCA GGATACTACGGAGATTATGTTTTCGATCGTGTATTAAAAGTTGATGTGAATAAAACTTTTAGCGGCATGG CTGCAACTCCTACGCAGGCTACAGGTAACGCAAGTAATACTAATCAGCCAGAAGCAAATGGCAGACCGAA CATCGCTTACGGAAGGCATATGCAAGATGCAGAGTGGTTTTCAAATGCAGCCTTCCTAGCCTTAAACATT TGGGATCGCTTCGACATTTTCTGCACCTTAGGGGCATCCAATGGATACTTCAAATCAAGTTCGGCTGCAT TCAACTTGGTTGGGTTAATAGGGTTTTCAGCTACCAGCTCAACCTCTACCGAGCTTCCAATGCAACTTCC TAACGTAGGCATTACCCAAGGTGTTGTGGAATTTTATACAGACACATCATTTTCTTGGAGCGTAGGTGCA CGTGGAGCTTTATGGGAATGTGGTTGTGCAACTTTAGGAGCTGAGTTCCAATACGCTCAATCTAATCCTA AGATTGAAGTGCTCAACGTCACTTCAAGCCCAGCACAATTTGTGATTCACAAACCAAGAGGCTATAAAGG AGCTAGCTCGAATTTTCCTTTACCTATAACGGCTGGAACAACAGAAGCTACAGACACCAAATCAGCTACA ATTAAATACCATGAATGGCAAGTAGGCCTCGCCCTGTCTTACAGATTGAATATGCTTGTTCCATATATTG GCGTAAACTGGTCAAGAGCAACTTTTGATGCTGATACTATCCGCATTGCTCAACCTAAATTAAAATCGGA GATTCTTAACATTACTACATGGAACCCAAGCCTTCTAGGATCAACCACTGCTTTGCCCAATAATGCTGGT AAGGATGTTCTATCTGATGTCTTGCAAATTGCTTCGATTCAGATCAACAAAATGAAGTCTAGAAAAGCTT GTGGTGTAGCTGTTGGTGCAACGTTAATCGACGCTGACAAATGGTCAATCACTGGTGAAGCACGCTTAAT CAATGAAAGAGCTGCTCACATGAATGCTCAATTCAGATTCTAAGGATTTAGTTTATACTATCCTAACTTT
Protein Sequence	>AAA17396.1 major outer membrane protein [Chlamydia psittaci] MKKLLKSALLFAATGSALSLQALPVGNPAEPSLLIDGTMWEGASGDPCDPCATWCDAISIRAGYYGDYVF DRVLKVDVNKTFSGMAATPTQATGNASNTNQPEANGRPNIAYGRHMQDAEWFSNAAFLALNIWDRFDIFC TLGASNGYFKSSSAAFNLVGLIGFSATSSTSTELPMQLPNVGITQGVVEFYTDTSFSWSVGARGALWECG CATLGAEFQYAQSNPKIEVLNVTSSPAQFVIHKPRGYKGASSNFPLPITAGTTEATDTKSATIKYHEWQV GLALSYRLNMLVPYIGVNWSRATFDADTIRIAQPKLKSEILNITTWNPSLLGSTTALPNNAGKDVLSDVL QIASIQINKMKSRKACGVAVGATLIDADKWSITGEARLINERAAHMNAQFRF
Molecule Role	Protective antigen
Molecule Role Annotation	Plasmid DNA (pcDNA1::MOMP A) expressing the major outer membrane protein (MOMP) of Chlamydophila psittaci genotype A strain 89/1051 has been tested for its ability to induce protective immunity against Cp. psittaci challenge in budgerigars. DNA immunisation significantly reduced clinical signs, macroscopic lesions, pharyngeal and cloacal excretion as well as chlamydial replication, even in the presence of pre-existing serum antibodies, as compared to the placebo-vaccinated controls (Harkinezhad et al., 2009).
References

MOMP