VIOLIN: Vaccine Investigation and Online Information Network

Vaccine Detail

Sputnik V

Vaccine Information

Vaccine Name: Sputnik V
Target Pathogen: SARS-CoV-2
Target Disease: COVID-19
Product Name: Gam-COVID-Vac
Vaccine Ontology ID: VO_0005168
Type: Recombinant vector vaccine
Status: Clinical trial
Host Species for Licensed Use: Human
Antigen: spike (S) protein (Logunov et al., 2020)
Immunization Route: Intramuscular injection (i.m.)
Description: A SARS-CoV-2 recombinant viral vector vaccine composed of Ad26 and Ad5 vectors expressing S protein that lyophilised (Logunov et al., 2020).

Host Response

References

Logunov et al., 2020: Logunov DY, Dolzhikova IV, Zubkova OV, Tukhvatullin AI, Shcheblyakov DV, Dzharullaeva AS, Grousova DM, Erokhova AS, Kovyrshina AV, Botikov AG, Izhaeva FM, Popova O, Ozharovskaya TA, Esmagambetov IB, Favorskaya IA, Zrelkin DI, Voronina DV, Shcherbinin DN, Semikhin AS, Simakova YV, Tokarskaya EA, Lubenets NL, Egorova DA, Shmarov MM, Nikitenko NA, Morozova LF, Smolyarchuk EA, Kryukov EV, Babira VF, Borisevich SV, Naroditsky BS, Gintsburg AL. Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia. Lancet (London, England). 2020; 396(10255); 887-897. [PubMed: 32896291].